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| 1 | IVF或ICSI周期卵巢过度刺激获取大量卵子并不会导致妊娠率降低显示文摘Objective: To investigate the possible negative effects of a strong ovarian response on oocyte quality.Design: Retrospective study.Setting: Tertiary academic center.Patient(s): A total of 1, 894 women (IVF, n = 1, 544; ICSI, n = 350) who underwent their first ovarian stimulation cycle during the period 1995- 2002.Intervention(s): Standardized controlled ovarian stimulation with urinary FSH or recombinant FSH after pituitary down- regulation, followed by IVF/intracytoplasmic sperm injection (ICSI) and ET.Main Outcome Measure(s): Fertilization rate, fraction of high- quality embryos, and implantation rate.Result(s): Using multivariate logistic regression, we analyzed the effect, expressed as an odds ratio (OR), of the number of oocytes obtained (i.e., ovarian response) on the outcome measures.No effect of the response on the ongoing implantation rate or fraction of high- quality embryos was observed.Both in IVF (OR = 0.81, 95% confidence interval [CI] 0.75- 0.87) and in ICSI (OR = 0.88, 95% CI 0.76- 1.00), a negative effect of increasing ovarian response was seen on the fertilization rate per oocyte obtained.However, no negative effect was observed on the fertilization rate per oocyte injected in ICSI (OR = 1.00, 95% CI 0.87- 1.14).The fraction of immature oocytes rises from 3.9% , in women with ≤ 3 oocytes, to 26% in women with > 20 oocytes.Conclusion(s): Oocytes from high responders contain a greater fraction of immature oocytes, but pregnancy outcome is not impaired. | Kok J.D. Looman C.W.N. Weima S.M. Te Velde E.R. 朱亮 | 2006 | 世界核心医学期刊文摘(妇产科学分册)2006，2，9： | 5 |
| 2 | A high number of oocytes obtained after ovarian hyperstimulation for in vitro fertilization or intracytoplasmic sperm injection is not associated with decreased pregnancy outcome显示文摘 | Kok JD Looman CWN Weima SM | 2006 | Fertil Steril2006，85，4： | 1 |
| 3 | Experimental investigation of the parameter dependency of the removal rate of thermochemically polished CVD diamond film 显示文摘 | Weima J A Fahmer W R Job R | 2001 | Journal of Solid State Electrochm2001，5，2： | 1 |
| 4 | EFL:Thermophilic Sulfate Redu- ction and Methangenesis with Methanolin aHi gh Rate Anaerobic Rearobic Reactor 显示文摘 | Alfons J M Stams Look W Hulshoff Pol | 2000 | Biotech biceng2000，67，： | 1 |
| 5 | FSH receptor genotype is associated with pregnancy but not with ovarian response in IVF 显示文摘 | Klinkert E R Te Velde E R Weima S | 2006 | Reprod Biomed Online2006，13，5： | 1 |
| 6 | A high number of oo- cytes obtained after ovarian hyperstimulation for in vitro fertilization or intracytoplasmic sperm injection is not associated with decreased pregnancy outcome 显示文摘 | Kok J D Looman C W Weima S M | 2006 | Fertil Steril2006，85，4： | 1 |
| 7 | FSHreceptor genotype is associated with pregnancy butnot with ovarian response in IVF 显示文摘 | Klinkert ER te Velde ER Weima S | 2006 | Reprod Bi-omed Online2006，13，5： | 1 |
| 8 | FSH receptor genotype is associated with pregnancy but not with ovarian response in IVF显示文摘 | Klinkert E R te Velde E R Weima S | 2006 | Reprod Biomed Online2006，13，5： | 1 |
| 9 | A high number of ooeytes obtained after ovarian hyperstimulation for in vitro fertilization or intracytoplasmic sperm injection is not associated with decreased pregnancy outcome 显示文摘 | Kok JD Looman CW Weima SM | 2006 | Fertil Steril2006，85，4： | 1 |
| 10 | The use of fixed distance embryo transfer after IVF/ICSI equalizes the success rates among physicians显示文摘 | van de Pas MM Weima S Looman CW | 2003 | Hum Reprod2003，81，4： | 1 |
| 11 | A high number of oocytes obtained after ovarian hyperstimulation for in vitro fertilization or intracytoplasmic sperm injection is not associated with decreased pregnancy outcome显示文摘 | Kok JD Looman CW Weima SM | 2006 | Fertil Steril2006，85，4： | 1 |
| 12 | A high number of oocytes obtained after ovarian hyperstimulation for in vitro fertilization or intracytoplasmic sperm injection is not associated with decreased pregnancy outcome controlled ovarian hyperstimulation (with GnRH agonist and rFSH) 显示文摘 | Kok JD Looman CW Weima SM | 2006 | Fertil Steril2006，85，4： | 1 |
| 13 | A high number of oocytes obtained after ovarian hyperstimulation for in vitro fertilization or intracytoplasmic sperm injection is not associated with decreased pregnancy outcome显示文摘 | KOK J D LOOMAN C W WEIMA S M | 2006 | Fertil Steril2006，85，4： | 1 |
| 14 | Galanin expression in neuropathic pain:friend or foe?显示文摘 | Ramer MS Weima MA Patricia G | 1998 | Ann NY Acad Sci1998，863，： | 1 |
| 15 | A randomized comparison of two ovarian stimulation protocols with gonadetropin-releasing hormone (GnRH) antagonist cotreatment for in vitro fertilization commenci- ng recombinant follicle-stimulating hormone on cycle day 2 or 5 with the standard longGnRH agonist protocol 显示文摘 | BroekmansFJ Weima SM&teVelde ER | 2003 | J Clin Endocrinol Metab2003，88，9： | 1 |
| 16 | Defects boost graphitization for highly conductive graphene films显示文摘Fabricating highly crystalline macroscopic films with extraordinary electrical and thermal conductivities from graphene sheets is essential for applications in electronics,telecommunications and thermal management.High-temperature graphitization is the only method known to date for the crystallization of all types of carbon materials,where defects are gradually removed with increasing temperature.However,when using graphene materials as precursors,including graphene oxide,reduced graphene oxide and pristine graphene,even lengthy graphitization at 3000℃can only produce graphene films with small grain sizes and abundant structural disorders,which limit their conductivities.Here,we show that high-temperature defects substantially accelerate the grain growth and ordering of graphene films during graphitization,enabling ideal AB stacking as well as a 100-fold,64-fold and 28-fold improvement in grain size,electrical conductivity and thermal conductivity,respectively,between 2000℃and 3000℃.This process is realized by nitrogen doping,which retards the lattice restoration of defective graphene,retaining abundant defects such as vacancies,dislocations and grain boundaries in graphene films at a high temperature.With this approach,a highly ordered crystalline graphene film similar to highly oriented pyrolytic graphite is fabricated,with electrical and thermal conductivities(~2.0×10~4 S cm~(-1);~1.7×10~3 W m~(-1)K~(-1))that are improved by about 6-and 2-fold,respectively,compared to those of the graphene films fabricated by graphene oxide.Such graphene film also exhibits a superhigh electromagnetic interference shielding effectiveness of~90 dB at a thickness of 10μm,outperforming all the synthetic materials of comparable thickness including MXene films.This work not only paves the way for the te chnological application of highly conductive graphene films but also provides a general strategy to efficiently improve the synthesis and properties of other carbon materials such as graphene fibers,carbon nanotube fibers,carbon fibers,polymer-derived graphite and highly oriented pyrolytic graphite. | Qing Zhang Qinwei Wei Kun Huang Zhibo Liu WeiMa Zehui Zhang Yanfeng Zhang Hui-Ming Cheng Wencai Ren | 2023 | National Science Review2023，10，7： | 1 |
| 17 | FSH receptor genotype isassociated with pregnancy but not with ovarian response in IVF显示文摘 | Klinkert ER Tevelde ER Weima S | 2006 | Heprod Bio Med2006，13，5： | 1 |
| 18 | A high number of oocytes obtained after ovarian hyperstimulation for in vitro fertilization or intracytoplasmic sperm injection is not associated with decreased pregnancy outcome显示文摘 | Kok J D Looman C W Weima S M | 2006 | Fertil Steril2006，85，4： | 1 |
| 19 | A high number of oocytes obtained after ovarian hyperstimulation for in vitro fertilization or intracytoplasmic sperm injection is not associated with decreased pregnancy outcome 显示文摘 | Kok J D Looman CW Weima SM | 2006 | Fertil Steril2006，85，4： | 1 |
| 20 | Broadband and noncontact capacitive transducer forultrasonic measurements in NDE显示文摘 | Liu ZQ WeiMA | 2009 | Proc of 7th APCNDT Shanghai2009，1，1： | 1 |
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