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| 1 | Angiogenesis in rabbit hepatic tumor after transcatheter arterial embolization显示文摘AIM: To investigate the effect of transcatheter arterial embolization (TAE) on angiogenesis of hepatic tumor.METHODS: Twenty New Zealand White rabbits were randomly divided into two groups of 10 each and VX2 carcinoma was implanted in the left medial lobes of the livers. Fourteen days later, a silicon catheter was inserted into the left hepatic artery of rabbit with VX2 hepatic tumor and infusion was performed via the hepatic artery using Lipiodol (the TAE group) or saline (the control group). Rabbits were sacrificed 7 d after treatment and tumor tissues were excised. Expression of vascular endothelial growth factor (VEGF) protein and microvessel density (MVD) of tumors were examined using immunohistochemistry. The staining intensity of VEGF was evaluated with a computer-assisted image-analyzer. Reverse transcription-polymerase chain reaction (RT-PCR) was used to detect the VEGF mRNA expression of tumors.RESULTS: MVD was higher in the TAE group compared with the control group (28.6±10.6 vs 16.3±6.9, P<0.01).Expression of VEGF protein was enhanced after TAE. The staining intensity of VEGF in the TAE group was 0.162±0.018,significantly higher than in the control group (0.142±0.01,P<0.01). At mRNA level, VEGF165 mRNA was significantly higher in the TAE group compared with the control group (2.58±0.42 vsl.99±0.21, P<0.001). MVD was well correlated to VEGF expression in both the TAE group (r=0.69, P<0.05) and the control group (r=-0.72, P<0.05).CONCLUSION: TAE promotes the development of neovascularization of residual tumors through up-regulation of VEGF expression, possibly due to hypoxic insult. | Xiao-FengLiao Ji-LinYi Xing-RuiLi WeiDeng Zhi-FangYang GengTian | 2004 | World Journal of Gastroenterology2004，10，13： | 11 |
| 2 | ‘GM‐gene‐deletor’: fused loxP‐FRT recognition sequences dramatically improve the efficiency of FLP or CRE recombinase on transgene excision from pollen and seed of tobacco plants显示文摘 | KemingLuo HuiDuan DegangZhao XuelianZheng WeiDeng YongqinChen C. NealStewart RichardMcAvoy XiangningJiang YanhongWu AigongHe YanPei YiLi | 2007 | Plant Biotechnology Journal2007，，2： | 3 |
| 3 | Solventless Friedel-Crafts Acylation under Microwave Activation显示文摘A novel catalytic system, ZnCl2 supported on alumina, was found to be an efficient and readily available medium for the solvent-free Friedel-Crafts acylation reactions under microwave irradiation. Good yields and high catalytic efficiencies were observed within short reaction times. Comparing with silica gel, alumina was more efficient under the same conditions. | WeiDENG YuXU QingXiangGUO | 2005 | Chinese Chemical Letters2005，16，3： | 2 |
| 4 | Cryptanalysis and improvement of a biometrics-based remote user authentication scheme using smart card显示文摘 | Xiong Li Niu Jianwei Wang Weideng | 2011 | Journal of Network and Computer Applications2011，，： | 1 |
| 5 | Green Preparation Process, Characterization and Antitumor Effects of Doxorubicin–BSA–Dextran Nanoparticles显示文摘 | WeiDeng JuanLi PingYao FenHe ChongHuang | 2010 | Macromol Biosci2010，，10： | 1 |
| 6 | Tightness of certain monomials显示文摘For a quantized enveloping algebra of finite type, one can associate a natural monomial to a dominant weight. We show that these monomials for types A5 and D4 are semitight(i.e., a Z-linear combination of elements in the canonical basis) by a direct calculation. | CUI WeiDeng | 2015 | Science China Mathematics2015，58，6： | 0 |
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