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| 1 | Emerging role of Hippo pathway in gastric and othergastrointestinal cancers显示文摘More evidence has underscored the importance of Hippo signaling pathway in gastrointestinal tissue homeostasis, whereas its deregulation induces tumorigenesis. Yes-associated protein 1(YAP1) and its close paralog TAZ, transcriptional co-activator with a PDZbinding motif, function as key effectors negatively controlled by the Hippo pathway. YAP1/TAZ exerts oncogenic activities by transcriptional regulation via physical interaction with TEAD transcription factors. In various cancers, Hippo pathway cross-talks with pro- or anti-tumorigenic pathways such as GPCR, Wnt/β-catenin, Notch and TGF-β signaling and is deregulated by multiple factors including cell density/junction and micro RNAs. As YAP1 expression is significantly associated with poor prognosis of gastric and other gastrointestinal cancers, detailed delineation of Hippo regulation in tumorigenesis provides novel insight for therapeutic intervention. In current review, we summarized the recent research progresses on the deregulation of Hippo pathway in the gastrointestinal tract including stomach and discuss the molecular consequences leading to tumorigenesis. | Wei Kang Alfred SL Cheng Jun Yu Ka Fai To | 2016 | World Journal of Gastroenterology2016，22，3： | 11 |
| 2 | Insulin Inhibits Dexamethasone Effect on Angiotensinogen Gene Expression and Induction of Hypertrophy in Rat Kidney Proximal Tubular Cells in High Glucose显示文摘 | Zhang SL Chen X Wei CC | 2002 | Endocrinology2002，143，： | 1 |
| 3 | Silicone gel-filled breastand testicular implant capsules : a histologic and immunophenotypicstudy显示文摘 | ALbondanzo SL Young VL Wei MQ | 1999 | Mod Pathol1999，12，7： | 1 |
| 4 | Laparoscopic hepatojejunos- tomy for biliary atresia显示文摘 | SL Liu Long L Wei C | 2009 | J Laparoendosc Adv Surg Tech A2009，19，： | 1 |
| 5 | Risk factors for acute esophagitis in non-small-cell lung cancer patients treated with concurrent chemotherapy and three-dimensional conformal radiotherapy 显示文摘 | Wei X Liu HH Tucker SL | 2006 | Int J Radiat Oncol Biol Phys2006，66，1： | 1 |
| 6 | Lead discovery using molecular docking显示文摘 | Shoichet BK McGovern SL Wei B | 2002 | Curr Opin Chem Biol2002，6，4： | 1 |
| 7 | Fabrication of star-shaped, thermo- sensitive poly ( N-isopropylacrylamide ) -cholic acid-poly ( -capro- lactone) copoly -mers and their self-assembled micelles as drug carriers显示文摘 | Chen WQ Wei H Li SL | 2008 | Polymer2008，49，： | 1 |
| 8 | Clinical evaluation of C7 spinal nerve transection: 21 patients with at least 2 years' follow-up显示文摘 | Chuang DC Cheng SL Wei FC | 1998 | Br J Plast Surg1998，51，4： | 1 |
| 9 | Risk factors for pericardial effusion in inoperable esophageal cancer patients treated with definitivechemoradiation therapy 显示文摘 | Wei X Liu HH Tucker SL | 2008 | Int J Radiat Oncol Biol Phys2008，70，3： | 1 |
| 10 | Bending of the Distraction Site During Mandibular Distraction Osteogenesis in the Rabbit:A Model for Studying Segment Control and Side Effects显示文摘 | Yen SL Wei S Li S | | 0，，： | 1 |
| 11 | Impact of toxicity grade and scoring system on the relationship between mean lung dose and risk of radiation pneumonitis in a large cohort of patients with non-small cell lung cancer 显示文摘 | Tucker SL Jin H Wei X | 2010 | Int J Radiat Oncol Biol Phys2010，77，3： | 1 |
| 12 | Motor and bladder dysfunctionsin patients with vertebral fractures at the thoracolumbar junction 显示文摘 | Chen SL Huang YH Wei TY | 2012 | Eur Spine J2012，21，5： | 1 |
| 13 | Proteolytic enzymes as a limitation for pulmonary absorption of insulin: in vitro and in vivo investigations 显示文摘 | Zhang Q Wei SL | 1999 | Int J Pharm1999，192，1： | 1 |
| 14 | ABCG transporters: structure, substrate specificities and physiological roles: a grief overview 显示文摘 | Velamakanni S Wei SL Janvilisri T | 2007 | J Bioenerg Biomembr2007，39，56： | 1 |
| 15 | Frontalis suspension using expanded polytetraflu-oroethylene : results of flifferent surgical designs 显示文摘 | Wei YH Liao SL | 2009 | J Fonnos Med Assoc2009，108，12： | 1 |
| 16 | Prevalence, risk fac- tors, and natural history of positional plagiocephaly: a system- atic review 显示文摘 | Bialocerkowski AE Vladusic SL Wei NC | 2008 | Dev Med Child Neurol2008，50，8： | 1 |
| 17 | An investigation of pulsatile release tablets with ethylcellulose and Eudragitl as film coating materials and cross-linked polyvinylpyrrolidone in the core tablets 显示文摘 | Fan TY Wei SL Yan WW | 2001 | J Control Release2001，77，3： | 1 |
| 18 | Risk factors for pericardial ef- fusion in inoperable esophageal cancer patients treated with defin- itive chemoradiation therapy 显示文摘 | Wei X Liu HH Tucker SL ct al | 2008 | lnt J Radiat Oncol Biol Phys2008，70，3： | 1 |
| 19 | Draft genome of the kiwifruit Actinidia chinensis 显示文摘 | Huang SX Ding J Deng DJ Tang W Sun HH Liu DY Zhang L Niu XL Zhang X Meng M Yu JD Liu J Han Y Shi W Zhang DF Cao SQ Wei ZJ Cui YL Xia YH Zeng HP Bao K Lin L Min Y Zhang H Miao M Tang XF Zhu YZ Sui Y Li GW Sun HJ Yue JY Sun JQ Liu FF Zhou LQ Lei L Zheng XQ Liu M Huang L Song J Xu CH Li JW Ye KY Zhong SL Lu BR He GH Xiao FM Wang HL Zheng HK Fei ZJ Liu YS | 2013 | Nat Commun2013，4，： | 1 |
| 20 | Oxidative stress-mediated up-regulation of myocardial ischemic preconditioning up-regulated protein 1 gene expression in H9c2 cardiomyocytes is regulated by cyclic AMP-response element binding protein显示文摘 | Qu SL Zhu HL Wei X | 2010 | Free Radic Biol Med2010，49，4： | 1 |
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