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| 1 | 补体B因子是代谢综合征模型代谢与心血管特征的一个决定因素显示文摘补体B因子(complenment factor B,CFB)在2型糖尿病及心血管病患者脂肪组织及血清中水平升高,但与疾病发病机制的因果关系不明确。自发性高血压大鼠(spontaneously hypertensive rats,SHR)脂肪组织及血清中CFB也升高。为明确CFB在代谢综合征中的作用,研究者在SHR中敲除Cfb基因。 | 赵狄 练桂丽 Coan PM Barrier M Alfazema N Carter RN Marion de Procé S Dopico XC Garcia Diaz A Thomson A Jackson-Jones LH Moyon B Webster Z Ross D Moss J Arends MJ Morton NM Aitman TJ | 2017 | 中华高血压杂志2017,25,8: | 3 |
| 2 | SOURCE RADIATION AND RESPONSES OF WAVE PROPAGATION显示文摘Recordings of seismic waves propagating from earthquake source to a station at the earth’s surface are a system response function. The convolution operator in time domain can be simplified as a multiplication operator in frequency domain. We discuss in frequency domain the separation of source, path and site effects for global scaling of earthquake source radiation. Also discussed are source scaling model, faulting mechanism, and the H/V inversion problems with crustal and near surface structures. Gross features of apparent source spectra appear to be not much region dependent although there may be difference between tectonic styles within a region of tectonic mixture for which we need further study as data accumulate. Vertical spectra may be a better approach to approximate source radiation, as it has less crustal amplification effects than horizontal spectra. The H/V ratio is evidently a comprehensive indicator of amplification effects from near surface to deep structure. This gives it potential as an inversion tool to deduce site crustal structure. | CHEN Sheng zao 1 and Gail M Atkinson 2 (1. Geomatrix Consultants, Inc., 2101 Webster St., 12 th Floor, Oakland, CA 94612, USA, formerly at Dept. Earth Sciences & Ottawa Carleton Geoscience Center, Carleton University, Ottawa, Canada 2. Dept. Ea | 2001 | Geotectonica et Metallogenia2001,25,1: | 2 |
| 3 | Evolution of endovascular mechanical thrombectomy for acute ischemic stroke显示文摘Acute ischemic stroke(AIS) is a common medical problem associated with significant morbidity and mortality worldwide. A small proportion of AIS patients meet eligibility criteria for intravenous thrombolysis(IVT) with recombinant tissue plasminogen activator, and its efficacy for large vessel occlusion is poor. Therefore, an increasing number of patients with AIS are being treated with endovascular mechanical thrombectomy when IVT is ineffective or contraindicated. Rapid advancement in catheter-based and endovascular device technology has led to significant improvements in rates of cerebral reperfusion with these devices. Stentrievers and modern aspiration catheters have now surpassed earlier generation devices in the degree and rapidity of revascularization. This progress has been achieved with no concurrent increase in risk of major complications or mortality, both when used alone or in combination with IVT. The initial randomized controlled trials comparing endovascular therapy to IVT for AIS failed to show superior outcomes with endovascular treatment, butkey limitations of each trial may limit the significance of these results to current practice. While endovascular devices and operator experience continue to evolve, we are optimistic that this will be accompanied by improvements in patient outcomes. This review highlights the major endovascular devices used in current practice and the trials which have investigated their efficacy. | Colin J Przybylowski Dale Ding Robert M Starke Christopher R Durst R Webster Crowley Kenneth C Liu | 2014 | World Journal of Clinical Cases2014,2,11: | 2 |
| 4 | Deep inferior epigastric perforator flap in breast reconstruction: experience with the first 50 flaps显示文摘 | Hamdi M Weiler-Mithoff EM Webster MH | 1999 | Plast Reconstr Surg1999,103,: | 1 |
| 5 | Oxidation protection for carbon fiber composites 显示文摘 | Westwood M E Webster J D Day R J | 1996 | Material Science1996,31,6: | 1 |
| 6 | Diagnosis of influenza in the community:relationship of clinical diagnosis to confirmed virological,serologic,or molecular detection of influenza显示文摘 | Hays J Webster A | 2001 | Arch Inter Med2001,161,17: | 1 |
| 7 | In vitro and in vivo characterization of small-colony variant of the primary form of Photortabdus luminescens MD显示文摘 | WEBSTER J M | 1998 | Applied and Environmental Microbiology1998,64,: | 1 |
| 8 | Hydroxuurea and radiation therapy in advaeed cervical cancer显示文摘 | Piver M S Barlow J J Webster J | 1974 | American Journal of Obstetrics and Gynecology1974,120,7: | 1 |
| 9 | Relative efficacy of intravenous immunoglobulin G in ameliorating thrombocytopenia induced by antiplatelet GP Ⅱ IbⅢa versus GPlbalpha antibodies 显示文摘 | Webster ML Sayeh E Crow M | 2006 | Blood2006,108,3: | 1 |
| 10 | A statistical analysis of conditional launch for gigabit ethernet links using multimode fiber显示文摘 | Webster M Raddatz L White I H et el | 1999 | J Lightwave Technol1999,17,9: | 1 |
| 11 | Individual differences in need for cognitive closure显示文摘 | Webster D M Kruglanski A W | 1994 | J Pers Soc Psychol1994,67,10: | 1 |
| 12 | Temperature and humidity dynamics of cutaneous and respiratory evaporation in pigeons,Columba livia显示文摘 | WEBSTER M D KING J R | 1987 | Journal of Comparative Physiology B1987,157,2: | 1 |
| 13 | H5N1 outbreaks and en- zooticinfluenza显示文摘 | Webster RG Peiris M Chen H | 2006 | Emerg Infect Dis2006,,12: | 1 |
| 14 | Hepatitis C显示文摘 | Daniel P Webster Paul Klenerman Geoffrey M Dusheiko | 2015 | The Lancet . 2015 (9973)2015,,9973: | 1 |
| 15 | Three-dimensional, nano-structured PLGA scaffolds for bladder tissue replacement applications显示文摘 | Pattison M A Wurster S Webster T J | 2005 | Biomaterials2005,26,15: | 1 |
| 16 | Residual stress field in a friction stir welded aluminum extrusion显示文摘 | P J Webster P A Browne G B M Vau-ghan P J Withers | 2000 | Materials Science Forum2000,,9: | 1 |
| 17 | Evidence that a'treatment-free interval of <6 months' does not equate with clinically defined platinum resistance in ovarian cancer or primary peritoneal carcinoma显示文摘 | Kennedy A Webster K | 1998 | J Can Res Clin Ooncol1998,124,6: | 1 |
| 18 | Review article: Portal vein thrombosis-new insights into aetiology and management 显示文摘 | Webster G J Burroughs A K Riordan S M | 2005 | Aliment Pharmacol Ther2005,21,1: | 1 |
| 19 | Glial fibrillary acidic protein mRNA levels in the cingulate cortex of individuals with depression,bipolar disorder and schizophrenia显示文摘 | Webster M J O′Grady J Kleinman J E | 2005 | Neuroscience2005,133,: | 1 |
| 20 | The isolation of a 22 kDa band after SDS-PAGE of Schistosoma mansoni adult worms and its use to demonstrate that IgE responses against the antigen(s) it contains are associated with human resistance to reinfection显示文摘 | Dunne DW Webster M Smith P | 1997 | Parasit Immunol1997,19,: | 1 |