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| 1 | Acrylic Acid-RGD as a Biomimetic Surface Modifier for Poly(ethylene terephthalate)显示文摘The development of the blood compatibility is important to biomaterials.The attachment of human umbilical vein endothelial cells (HUVECs) on substrates that had been covalently grafted with the cell adhesion peptides Arg Gly Asp(RGD) was investigated. The immobilization of the peptide sequences at the surfaces of biomaterials, such as poly(ethylene terephthalate) (PET), is difficult due to an absence of functional groups to support covalent attachment. It is demonstrated a novel method to overcome this problem, by attach the RGD to acrylic acid(AAC), which immobilizes the sequence through adsorption at the PET surface. When coated by AAC RGD, the human umbilical vein endothelial cells (HUVECs) seeded upon the modified PET showed a marked increase in spreading over unmodified PET. The peptides were grafted using two steps: conjugation of AAC with PET film; reaction with PET AAC and immobilization of cell binding peptides RGD. The RGD grafted surface was characterized by X ray photoelectron spectroscopy(XPS) and contact angle measurements. Cell spreading is observed by optional microscopy and scanning electron microscope(SEM). Potentially, this is a feasible method of surface modification that can design many different types of biomaterials with a variety of biomolecules. | QIU Kai 1 , WAN Chang xiu 1 , CHEN Xin 1,LI Tian quan 2 This materials is based upon the work supported under the National Nature Science Fund project of China(29874022) 1 Department of Polymer Science and Engneering, Sichuan University,Chengdu 610065,China 2 Department of Chemistry, Sichuan University,Chengdu 610065,China | 2003 | Chinese Journal of Biomedical Engineering(English Edition)2003，12，1： | 1 |
| 2 | Scleralmaelting 16 years after pterygium excision with topicalMitomycin C adjuvant therapy显示文摘 | Wan Norliza WM Raihan IS Azwan JA | 2006 | Cont Lens Anterior Eye2006，29，： | 1 |
| 3 | Aspergillus fumi- gates evades immune recognition during germination through loss of toll-like receptor-4-mediated signal transduction 显示文摘 | Netea MG Wan'is A Van der Meet JW | 2003 | J Infect Dis2003，188，2： | 1 |
| 4 | Oral lichen planus:Progress in understanding its malignant potential and the implications for clinical management显示文摘 | Epstein JB Wan IS Gorsky M | 2003 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod2003，96，1： | 1 |
| 5 | Low frequency ultrasonic multi-mode Lamb wave method for characterizing the ultra-thin transversely isotropic laminate composite: Theory and experiment显示文摘A low-frequency multi-mode ultrasonic Lamb wave method suitable for character- izing the thickness, the density and the elastic constants of the ultra-thin transversely isotropic laminate composite is presented. The 'ultra-thin' here means that the thickness of the plate is much less than the wavelength of the ultrasonic wave so that the echoes from the front and back faces of the plate can’t be separated in the time domain. The dispersion equations for the low frequency ultrasonic Lamb waves with the propagation directions parallel and vertical to the fiber direction are derived. In conjunction with the least square algorithm method, the secant algorithm is used to estimate the parameters of the ultra-thin fiber-reinforced composite layer. The evaluation errors and the sensitivity of the method to different paramters of the thin composite are analyzed. The technique has been used to characterize the ultra-thin grass fiber reinforced PES composite with thickness down to ten percents of the ultrasonic wavelength. It is observed that the agreement between the nominal and the estimation values is reasonably good. | ZHANG Rui, WAN Mingxi, CHEN Xiao, (Department of Biomedical Engineering Xi’an Jiaotong University Xi’an 710049) CAO Wenwu is with the Intercollege Materials Research Laboratory The Pennsylvania State University University Park, PA, 16802, USA | 2001 | Chinese Journal of Acoustics2001，20，4： | 1 |
| 6 | Scleral mehing 16 years after pterygium excision with topical Mitomycin C adjuvant therapy 显示文摘 | Wan Norliza WM Raihan IS Azwa JA | 2006 | Cont Lens Anterior Eye2006，29，4： | 1 |
| 7 | The membrane-eytoskeleton osteosarcoma metastasis 显示文摘 | Khanna C Wan X Bose S Linker Ezrin is necessary for | 2004 | NatMed2004，10，2： | 1 |
| 8 | New Development of East Asian Regional Cooperation and Its Prospects显示文摘East Asian regional cooperation is advancing with the concerted efforts of various parties.It not only conforms to the world development trend,but also is the objective reflection of the historical development of countries in the region.At ASEAN-related summits held in late October 2009,the concept | Wan Lingying is Associate Research Fellow at China Institute of International Studies | 2010 | China International Studies2010，30，4： | 0 |
| 9 | Human Rights Protection for Prisoners:Its Features and Evolution——In commemoration of the 20th anniversary of the Publication of the White Paper on China’s Criminal Reform Situation显示文摘China put forward the concept of human rights protection for prisoners as part of the modernization of its prison system. On nov. 1, 1991, the Chinese government published the white paper 'human Rights in China' and it showed that human rights theories and practices in China fully embody the basic spirit and requirements set forth in the Universal Declaration of Human Rights. On august 11, 1992, the | WAN YIWEN is from Jiangsu Prison Management Bureau | 2012 | The Journal of Human Rights2012，11，5： | 0 |
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