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| 1 | Hepatitis B virus genotypes and lamivudine resistance mutations in Jordan显示文摘AIM:To investigate and identify prevalent hepatitis B virus(HBV) genotypes and to explore lamivudine-resistant mutations among treated and untreated patients in Jordan.METHODS:A total of 107 cases with chronic hepatitis B were recruited from different medical centers in Jordan.Serological tests were preformed for all cases using a microparticle enzyme immunoassay.HBV Genotyping was performed for 70 cases using Line probe genotyping assay.The YMDD mutations were explored for 20 cases(4 were lamivudine naive) using the INNO-LiPA HBV DR assay.RESULTS:Genotype D was the only detected genotype.A total of 6 YMDD mutations were detected in 5 treated patients(31%) while one mutation was detected in the naive patients.Seventeen percent of cases were positive for HBeAg and had statistically significant higher levels of serum aminotransferases.CONCLUSION:HBV genotype D appears to be the only circulating type in Jordanian patients.The YMDD mutations were detected in 31% of lamivudine-treated cases with similar patterns to those found in the literature.We also found a relatively low prevalence of HBeAg expression among examined cases(17%).Awareness of these serologic,genotypic and resistance patterns might help in the formulation of management plans and for predicting clinical outcomes.Further larger scale studies are needed to confirm our results and to examine possible associations among clinical,serologic,and genetic patterns of HBV infections in Jordan. | Hani A Masaadeh Wail A Hayajneh Enayat A Alqudah | 2008 | World Journal of Gastroenterology2008，14，47： | 10 |
| 2 | Ketamine and midazolam sedation for pediatric gastrointestinal endoscopy in the Arab world显示文摘AIM:To evaluate the safety and effectiveness of intravenous ketamine-midazolam sedation during pediatric endoscopy in the Arab world.METHODS:A retrospective cohort study of all pediatric endoscopic procedures performed between 2002-2008 at the shared endoscopy suite of King Abdullah University Hospital,Jordan University of Science & Technology,Jordan was conducted.All children were > 1 year old and weighed > 10 kg with American Society of Anesthesiologists class 1 or 2.Analysis was performed in terms of sedation-related complications(desaturation,respiratory distress,apnea,bradycar-dia,cardiac arrest,emergence reactions),adequacy of sedation,need for sedation reversal,or failure to complete the procedure.RESULTS:A total of 301 patients(including 160 males) with a mean age of 9.26 years(range,1-18 years) were included.All were premedicated with atropine;and 79.4%(239/301) had effective and uneventful sedation.And 248(82.4%) of the 301 patients received a mean dose of 0.16 mg/kg(range,0.07-0.39) midazolam and 1.06 mg/kg(range,0.31-2.67) ketamine,respectively within the recommended dosage guidelines.Recommended maximum midazolam dose was exceeded in 17.6% patients [34 female(F):19 male(M),P = 0.003] and ketamine in 2.7%(3 M:5 F).Maximum midazolam dose was more likely to be exceeded than ketamine(P < 0.001).Desaturation occurred in 37(12.3%) patients,and was reversible by supplemental oxygen in all except 4 who continue to have desaturation despite supplemental oxygen.Four(1.3%) patients had respiratory distress and 6(2%) were difficult to sedate and required a 3rd sedative;12(4%) required reversal and 7(2.3%) failed to complete the procedure.None developed apnea,bradycardia,arrest,or emergence reactions.CONCLUSION:Ketamine-midazolam sedation appears safe and effective for diagnostic pediatric gastrointestinal endoscopy in the Arab world for children aged > 1 year and weighing > 10 kg without co-morbidities. | Mohamad-Iqbal S Miqdady Wail A Hayajneh Ruba Abdelhadi Mark A Gilger | 2011 | World Journal of Gastroenterology2011，17，31： | 5 |
| 3 | Chemical analysis and antioxidant content of various propolis samples collected from different regions and their impact on antimicrobial activities显示文摘Objective: To assess the antioxidant content, antimicrobial and antioxidant activities of various propolis samples. Methods: Seven propolis samples were collected from different locations in Morocco, which are characterized by different plant predominant vegetations. The resin, wax and balsam of hydroalcoholic extract of propolis content were identified, and the antioxidant content was analyzed with the use of HPLC and colorimetric methods. The antioxidant activity was assessed by DPPH, ABTS.^+ and ferric reducing power assays. The antimicrobial activity was assessed against bacterial species, including methicillin resistant Staphylococcus aureus and Candida albicans, and expressed as the minimal inhibitory concentration. Results: The propolis samples showed significant variations in the chemical composition and in the antioxidant or antimicrobial activities even when the samples were collected from the same location. Propolis with high resin and low wax content had high level of antioxidant compounds, and strong antioxidant and antimicrobial activities. Gram-positive bacteria, especially, methicillin resistant Staphylococcus aureus were more sensitive to all propolis samples than Gram-negative bacteria and Candida albicans. Conclusions: The chemical composition and the antioxidant and antimicrobial activities of various propolis samples are different and rely on the geographic and plant origin of propolis collection. Propolis samples with low wax and high resin content might be more suitable to be used in future preclinical or clinical investigations. | Soumaya Touzani Noori Al-Waili Nawal El Menyiy Bratko Filipic Adriana Pereyra Ilham EL Arabi Wail Al-Waili Badiaa Lyoussi | 2018 | Asian Pacific Journal of Tropical Medicine2018，11，7： | 2 |
| 4 | 氮硫共掺杂多孔碳材料的制备及其在锂硫电池中的应用显示文摘锂硫电池因其较高的理论容量和对环境友好等优势被视为极具发展潜力的储能装置,但是多硫化物的穿梭效应极大地限制了锂硫电池的实际应用。本文以葡萄糖为碳源,离子液体为氮源和硫源,KCl和ZnCl_(2)为模板剂,KOH为活化剂,通过热解工艺合成了氮硫共掺杂多孔碳(NSPC)。XPS和极性吸附实验表明N、S杂原子成功引入并且提高了碳材料对多硫化物的吸附能力,有效缓解多硫化物的穿梭效应,而较高的比表面积(1290.67 m^(2)·g^(-1))有助于提高硫负载量。负载70.1wt.%的硫后(S@NSPC)作为锂硫电池的正极材料表现出了良好的电化学性能。在167.5 mA·g^(-1)的电流密度下S@NSPC的首次放电容量为1229.2 mAh·g^(-1),远高于S@PC的861.6 mAh·g^(-1),且S@NSPC循环500圈后容量为328.1 mAh·g^(-1)。当电流密度从3350 mA·g^(-1)恢复至167.5 mA·g^(-1)时,可逆容量达到首圈放电比容量的80%,几乎恢复至其初始值。 | 赵桂香 Wail Hafiz Zaki Ahmed 朱福良 | 2021 | 电化学2021，27，6： | 2 |
| 5 | Rates and patterns of contemporary floodplain sedimentation: A case study of the River Culm, Devon, UK显示文摘 | Wailing D E Bradley S B | 1989 | Geo- Journal1989，19，1： | 1 |
| 6 | Calibration of Caesium-137 meas urements to provide quantitative erosion rate data 显示文摘 | Wailing D E Quine T A | 1990 | Land Degradation and Rehabilitation1990，2，： | 1 |
| 7 | Implementation of position force and position position teleoperator controllers with steel rope driven mechanisms显示文摘 | LAU H Y K WAIL C C | 2005 | Robotics and Computer Integrated Manufacturing2005，21，： | 1 |
| 8 | End-stage renal disease,at herosclerosis,and cardio- vascular mortality:is C-reactive protein the missing link?显示文摘 | Arici M Wails J | 2001 | Kidney Int2001，59，2： | 1 |
| 9 | Sternocleidomastoid Muscle Flap Preventing Frey Syndrome following Parotidectomy显示文摘 | Wail Queiroz Filho Rogério A. Dedivitis M.D. Ph.D. Abr?o Rapoport M.D. Ph.D. André V. Guimar?es | 2004 | World Journal of Surgery2004，，4： | 1 |
| 10 | Altered regulation of phophatidylinositol 3-kinase signaling in cathepsin D-deficient brain显示文摘 | Wails K C Klocke B J Saftig P | 2007 | Autophagy2007，3，3： | 1 |
| 11 | Biological concepts of prolonged neoadjuvant treatment plus GM-CSF in locally advanced tumors显示文摘 | Pinedo HM de Gruijl TD van Der Wail E | 2000 | Oncologist2000，5，6： | 1 |
| 12 | A Comprehensive Medical Simulation Education Curriculum for Emergency Medicine Residents显示文摘 | Binstadt ES Wails RM White BA | 2007 | Ann Emerg Med2007，49，4： | 1 |
| 13 | Manipulation of the Toll-Like Receptor 7 Signaling Pathway by Epstein-Barr Virus 显示文摘 | Martin H J Lee JM Wails D | 2007 | J Virol2007，81，18： | 1 |
| 14 | Oxidation of mandelic acid by Fenton' s reagent显示文摘 | WAILING C AMRANTH K | 1982 | J Am Chem Soc1982，104，： | 1 |
| 15 | Trivial intersection groups显示文摘 | Wails G | 1979 | Arch Math1979，32，1： | 1 |
| 16 | Ethical investment process and outcomes显示文摘 | Michelson G Wailes N Laan S Forst G | | 0，，： | 1 |
| 17 | A shadow-price frontier measurement of profit efficiency in Chinese agriculture 显示文摘 | WANG J CRAMER G L WAILES E | 1996 | American journal of agricultural economics1996，78，1： | 1 |
| 18 | Uric acid as a risk factor for Cardiovascular diseases显示文摘 | WAILING W S WEBB D J MAXWELL S R | 2000 | Q J M2000，93，11： | 1 |
| 19 | Mapping of quantitative trait loci for growth and carcass traits in commercial sheep population 显示文摘 | Wailing G A Visscher P M Wilson A D | 2004 | Journal of Animal Science2004，，82： | 1 |
| 20 | The learning region: The impact of social capital and weak ties on innovation显示文摘 | Christoph Hauser Gottfried Tapeline Janette wailed | 2007 | Regional studies2007，，2： | 1 |
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