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| 1 | Educated consumers don't believe artificial meat is the solution to the problems with the meat industry显示文摘The production of in vitro meat by cell culture has been suggested by some scientists as one solution to address the major challenges facing our society. Firstly, consumers would like the meat industry to reduce potential discomfort of animals on modern farms, or even to avoid killing animals to eat them. Secondly, citizens would like meat producers to reduce potential environmental deterioration by livestock and finally, there is a need to reduce world hunger by increasing protein resources while the global population is predicted to grow rapidly. According to its promoters, artificial meat has a potential to make eating animals unnecessary, to reduce carbon footprint of meat production and to satisfy all the nutritional needs and desires of consumers and citizens. To check these assumptions, a total of 817 educated people(mainly scientists and students) were interviewed worldwide by internet in addition to 865 French educated people. We also interviewed 208 persons(mainly scientists) after an oral presentation regarding artificial meat. Results of the three surveys were similar, but differed between males and females. More than half of the respondents believed that 'artificial meat' was feasible and realistic. However, there was no majority to think that artificial meat will be healthy and tasty, except respondents who were in favour of artificial meat. A large majority of the respondents believed that the meat industry is facing important problems related to the protection of the environment, animal welfare or inefficient meat production to feed humanity. However, respondents did not believe that artificial meat will be the solution to solve the mentioned problems with the meat industry, especially respondents who were against artificial meat. The vast majority of consumers wished to continue to eat meat even they would accept to consume less meat in a context of increasing food needs. Only a minority of respondents(from 5 to 11%) would recommend or accept to eat in vitro meat instead of meat produced from farm animals. Despite these limitations, 38 to 47% of the respondents would continue to support research on artificial meat, but a majority of them believed that artificial meat will not be accepted by consumers in the future, except for respondents who were in favour of artificial meat. We speculated that the apparent contradictory answers to this survey expressed the fact that people trust scientists whoare supposed to continuously discover new technologies potentially useful in a long term future for the human beings, but people also expressed concern for their health and were not convinced that artificial meat will be tasty, safe and healthy enough to be accepted by consumers. | Aurélie Hocquette Carla Lambert Clémentine Sinquin Laure Peterolff Zoé Wagner Sarah P F Bonny André Lebert Jean-Franois Hocquette | 2015 | Journal of Integrative Agriculture2015，14，2： | 11 |
| 2 | Sex-specific effects of Eugenia punicifolia extract on gastric ulcer healing in rats显示文摘AIM To evaluate the sex-specific effects of a hydroalcoholic extract from Eugenia punicifolia(HEEP) leaves on gastric ulcer healing.METHODS In this rat study involving males, intact(cycling) females, and ovariectomized females, gastric ulcers were induced using acetic acid. A vehicle, lansoprazole, or HEEP was administered for 14 d after ulcer induction. Body weight was monitored throughout the treatment period. At the end of treatment, the rats were euthanized and the following in vivo and in vitro investigations were performed: macroscopic examination of the lesion area and organ weights, biochemical analysis, zymography, and evaluation of protein expression levels. Additionally, the concentration-dependent effect of HEEP was evaluated in terms of subacute toxicity and cytotoxicity.RESULTS Compared to the vehicle, HEEP demonstrated a great healing capacity by substantially reducing the ulcerative lesion area in males(52.44%), intact females(85.22%), and ovariectomized females(65.47%), confirming that HEEP accelerates the healing of acetic acidinduced gastric lesions and suggesting that this effect is modulated by female sex hormones. The antiulcer effect of HEEP was mediated by prostaglandin E2 only in male rats. Overall, the beneficial effect of HEEP was the highest in intact females. Notably, HEEP promoted the expression of vascular endothelial growth factor(intact vs ovariectomized females) and decreased the expression of Caspase-8 and Bcl-2(intact female vs male or ovariectomized female). Additionally, HEEP enhanced fibroblast proliferation and migration into a wounded area in vitro, confirming its healing effect. Finally, no sign of subacute toxicity or cytotoxicity of HEEP was observed.CONCLUSION In gastric ulcers, HEEP-induced healing(modulated by female sex hormones; in males, mediated by prostaglandin) involves extracellular matrix remodeling, with gastric mucosa cell proliferation and migration. | Larissa Lucena Périco Vinícius Peixoto Rodrigues Rie Ohara Gabriela Bueno Vania Vasti Alfieri Nunes Raquel Cássia dos Santos Ana Carolina Lima Camargo Luis Antuio Justulin Joior Sérgio Faloni de Andrade Viviane Miranda Bispo Steimbach Luísa Mota da Silva Lúcia Regina Machado da Rocha Wagner Vilegas Catarina dos Santos Clélia Akiko Hiruma-Lima | 2018 | World Journal of Gastroenterology2018，24，38： | 3 |
| 3 | Moderate hypothermia in neonatal encephalopathy:efficacy outcomes显示文摘 | Eicher DJ Wagner CL Katikaneni LP | 2005 | Pediatr Neural2005，32，： | 1 |
| 4 | The impact of prenatal drug exposure on the neonate显示文摘 | Wagner CL Katikanen LD Cox TH | 1998 | Obstet Gynecol Clin North Am1998，25，： | 1 |
| 5 | The impact of prenatal drug exposure on the neonate显示文摘 | Katikanen LD Cox TH | 1998 | Obstet Gynecol elin North Am1998，25，5： | 1 |
| 6 | Prevention of rickets and vitamin D deficiency in infants, children, and adolescents显示文摘 | Wagner CL Greer FR | 2008 | Pedia trics2008，122，5： | 1 |
| 7 | Prevention of rickets and vitamin Ddeficiency in infants, children, and adolescents显示文摘 | Wagner CL | 2008 | Pediatrics2008，122，5： | 1 |
| 8 | High-throughput copy number analysis of 17q23 in 3520 tissue specimens by fluorescence in situ hybridization to tissue microarrays显示文摘 | Andersen CL Monni O Wagner U | 2002 | Am J Pathol2002，161，1： | 1 |
| 9 | Vitamin D status as related to race and feeding type in preterm infants显示文摘 | Taylor SN Wagner CL Fanning D | 2006 | Breastfeed Med2006，1，3： | 1 |
| 10 | Prevention of rickets and vitamin D deficiency in infants, children, and adolescents 显示文摘 | Wagner CL Greet FR | 2008 | Pediat tics2008，122，5： | 1 |
| 11 | Vitamin D and mood disorders among women : an integrative review 显示文摘 | Murphy PK Wagner CL | 2008 | Midwifery Womens Health2008，53，5： | 1 |
| 12 | Prevention of rickets and vitamin D deficiency in infants, children, and adolescents显示文摘 | Wagner CL Greer FR American Academy of Pediatrics Section on Breastfeeding American Academy of Pediatrics Committee on Nutrition | 2008 | Pediatrics2008，122，5： | 1 |
| 13 | Nutrition in the neonatal intensive care unit:how do we reduce the incidence of extrauterine growth restriction ? 显示文摘 | Clark RH Wagner CL Merritt RJ | 2003 | J Perinatol2003，23，4： | 1 |
| 14 | Nutritional vitamin D status during pregnancy:reasons for concern显示文摘 | Hollis BW Wagner CL | | 0，，： | 1 |
| 15 | Quercitrin,a glycoside form of quercetin,prevents lipid peroxidation in vitro显示文摘 | Wagner C Fachinetto R Dalla Corte CL | 2006 | Brain Res2006，1107，1： | 1 |
| 16 | Maternal vitamin D andfetal growth in early-onset severe preeclampsia 显示文摘 | Robinson CJ Wagner CL Hollis BW | 2011 | Am J Obstet Gy-necol2011，204，6： | 1 |
| 17 | Assessment of dietary vitamin D require- mentsduring pregnancy and lactation显示文摘 | Hollis BW Wagner CL | 2004 | Am J Clin Nutr2004，79，5： | 1 |
| 18 | Nutritional vitamin D status during pregnancy: reasons for concern 显示文摘 | Hollis BW Wagner CL | 2006 | CMAJ2006，174，9： | 1 |
| 19 | Assessment of dietary vitamin D requirementsduring pregnancy and lactation显示文摘 | Hollis BW Wagner CL | 2004 | Am J Clin Nutr2004，79，5： | 1 |
| 20 | Assessment of dietary vitamin D requirements during pregnancy and lactation 显示文摘 | Hollis BW Wagner CL | 2004 | Am J Clin Nutr2004，79，5： | 1 |
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