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| 1 | Existence of the Uniformly Minimum Risk Unbiased Estimator in Seemingly Unrelated Regression System | Wu Qiguang Institute of Systems Science Academia Sinica Beijing,100080 China | 1995 | Acta Mathematica Sinica,English Series1995，11，1： | 3 |
| 2 | A new kind of magnetic targeting induction heating drug carrier and its physical and biological properties显示文摘Nano-carbon and iron composite―carbon-coated iron nanoparticles (CCINs) produced by carbon arc method can be used as a new kind of magnetic targeting induction heating drug carrier for cancer therapy. The structure and morphology of CCINs are studied by X-ray diffraction (XRD) and transmission electron microscope (TEM). Mossbauer spectra of these nanoparticles show that they contain only iron and carbon, without ferric carbide and ferric oxide. CCINs can be used as the magnetic drug carrier, with the effect of targeting magnetic induction heating in its inner core and higher drug adsorption in its nano-carbon shell outside because of its high specific surface area. CCINs can absorb Epirubicin (EPI) of 160 μg/mg measured by an optical spectrometer. In acute toxicity experiment with mice, the median lethal dose (LD50) of EPI is 16.9 mg/kg, while that of EPI-CCINs mixture is 20.7 mg/kg and none of the mice died after pure CCINs medication. The results show that pure CCINs belong to non-toxic grade and EPI delivery in mixture with CCINs can reduce its acute toxicity in mice. The magnetic properties of CCINs and their magnetic induction heating are investigated. The iron nanoparticle in its inner core has better magnetism with a good effect on targeting magnetic induction heating. When the CCINs are mixed with physiological salt water and are injected uniformly in pig's liver, the temperature goes up to 48℃. While in the case that CCINs are filled in a certain section of pig's liver, the temperature goes up to 52℃. In both cases the temperature is high enough to kill the cancer cell. CCINs have potential applications in cancer therapy. | ZHANG HaiYan CHEN YiMing ZHENG Yun LAO XiangMing ZENG GuoXun PANG JinShan WU QiGuang LI JinQing | 2009 | Science China(Technological Sciences)2009，52，10： | 2 |
| 3 | Low temperature catalytic combustion of chlorobenzene over Mn–Ce–O/γ-Al 2 O 3 mixed oxides catalyst显示文摘 | Meng Wu Xingyi Wang Qiguang Dai Yaoxing Gu Dao Li | 2010 | Catalysis Today2010，，： | 1 |
| 4 | Several results on admissibility of a linear estimate of stochastic regression coefficients and parameters显示文摘 | Wu qiguang | 1988 | ActaMathematicae Applicatae Sinica1988，11，1： | 1 |
| 5 | Low temperature catalytic combustion of cholrobenzene over Mn-Ce-O/),-AI203 mixed oxides catalyst 显示文摘 | Wu Meng Wang Xingyi Dai Qiguang | 2010 | Cat- al Today2010，158，34： | 1 |
| 6 | Three-dimensional theoretical analysis of seepage field in front of shield tunnel face显示文摘To evaluate hydraulic head distribution in front of a shield tunnel in a saturated soil layer,theoretical analysis and numerical simulations are carried out in this study.Based on the partial differential equilibrium equation of seepage flow,a three-dimensional(3D)theoretical analytical model of the shield tunnel face and the seepage field in front of it is established using the eigenfunction and the Fourier series expansion methods,and the hydraulic head calculation formula is derived.Combined with engineering cases,the theoretical analysis results and the 3D numerical simulation results are compared and analyzed.The effect of the water pressure of the tunnel face on the hydraulic head distribution is also analyzed.The results of the proposed analytical solution are in agreement with those of the numerical simulation solutions;moreover,the proposed analytical solution requires less time to calculate the seepage hydraulic head than the numerical simulation.The ratio of the initial water table to the diameter(D)of tunnel face has a more significant impact on the hydraulic head distribution at a position 0.5D above the tunnel vault.When the water pressure on the tunnel face is not considered,the values of the hydraulic head are significantly underestimated. | Qiguang Di Pengfei Li Mingju Zhang Caixia Guo Fan Wang Jie Wu | 2022 | Underground Space2022，7，4： | 1 |
| 7 | Low temperature catalytic combustion of chlorobenzene over Mn–Ce–O/γ-Al 2 O 3 mixed oxides catalyst显示文摘 | Meng Wu Xingyi Wang Qiguang Dai Yaoxing Gu Dao Li | 2010 | Catalysis Today2010，，3： | 1 |
| 8 | Catalyt- ic combustion of chlorobenzene over Mn-Ce/A120z eat-alyst promoted by Mg显示文摘 | Meng Wu Xingyi Wang Qiguang Dai Dao Li | 2010 | Catalysis communications2010，11，： | 1 |
| 9 | Admissibility of quadratic estimates of error variance in linear models 显示文摘 | Wu Qiguang Cheng Ping Li Guoying | 1982 | Scientia Sinica1982，25，： | 1 |
| 10 | A new discovered ABCA1 gene polymorphisms and the association of ABCA1 SNPs with coronary artery disease and plasma lipids in Chinese population显示文摘Objective: Single nucleotide polymorphisms (SNP) of ATP-binding cassette transporter A1 (ABCA1) gene are related to plasma lipid and susceptibility to coronary artery disease (CAD). Our first goal was to screen all 50 coding regions of ABCA1 to find new SNPs. Our second goal was to investigate the frequency distribution of R1587K and M883I polymorphisms of ABCA1 gene, which are the variant occurred most frequently, in Chinese people and to evaluate their association with the CAD phenotype and plasma lipids. Methods: Single-strand conformation polymorphism (SSCP) and DNA sequence were used for confirming new SNP of ABCA1, and restriction fragment length polymorphism (RFLP) were applied for confirming genotypes of R1587K and M883I in 112 CAD cases and 108 healthy people. Results: We discovered a new ABCA1 SNP in Chinese population, which converse 233 amino acids from Methionine to Valine (M233V). This new ABCA1 SNP located in exon7, and might potentially modulate the biological function of lipid metabolism. For R1587K and M883I SNPs, the K allele and I allele frequency was 28.9%and 31.1%, respectively. The K allele at R1587K conferred lower mean values of HDL-C in a dose-dependent manner in both CAD patients and healthy people. However, 883I allele was not associated with plasma lipid level. Neither 1587KK nor 883II associated with increased risk of CAD. Conclusion: Our study finds a potential functional ABCA1 SNPs and revealed K allele of R1587K associated decreased HDL-C level in Chinese population. | Guo Zhigang Wu Pingsheng Xie Di Wang Qiguang Liu Yayang Cha Zheng Li Peng Lai Wenyan Tu Yan | 2011 | Journal of Medical Colleges of PLA(China)2011，26，4： | 1 |
| 11 | ADMISSIBILITY AND Г-MINIMAXITY OF LOSSESTIMATORS IN MULTIVARIATE LINEAR MODEL显示文摘Let an n x m matrix of observations, Y, have distribution N(XB, G V),where X, G > 0 and V > 0 are known n x p) n x n and m x m matrices respectively,B is an unknown P x m matrix of parameters. We consider the problem of estimatingthe loss L = (SXB - SXB)C(SXB - SXB)’, where S and C > 0 are known t x n andm x m matrices respectively B = (X’G-’X)-X’G-’y It is pr0ved that the uniformlyminimum risk unbiased estimator of L, L. = (trCV)SX(X’G-’X)-X’S’, is admissiblefor q = rankSX = 1 and m 4, or for q 2 and m 2 and inadmissible for m 5 witha matrix loss function. It is also shown that the above Lo is a r-minimax estimator 0f Lagainst a class of priors. | Kazuo Noda(Department of Mathematics, Science University of Tokyo, Tokyo, Japan 162)WU Qiguang(Institute of Systetns Science, Academia Sinica, Beijing 100080, China) | 1998 | Systems Science and Mathematical Sciences1998，11，1： | 0 |
| 12 | Evolutionary Multitask Optimization in Real-World Applications: A Survey显示文摘Because of its strong ability to solve problems,evolutionary multitask optimization(EMTO)algorithms have been widely studied recently.Evolutionary algorithms have the advantage of fast searching for the optimal solution,but it is easy to fall into local optimum and difficult to generalize.Combining evolutionary multitask algorithms with evolutionary optimization algorithms can be an effective method for solving these problems.Through the implicit parallelism of tasks themselves and the knowledge transfer between tasks,more promising individual algorithms can be generated in the evolution process,which can jump out of the local optimum.How to better combine the two has also been studied more and more.This paper explores the existing evolutionary multitasking theory and improvement scheme in detail.Then,it summarizes the application of EMTO in different scenarios.Finally,according to the existing research,the future research trends and potential exploration directions are revealed. | Yue Wu Hangqi Ding Benhua Xiang Jinlong Sheng Wenping Ma Kai Qin Qiguang Miao Maoguo Gong | 2023 | Journal of Artificial Intelligence and Technology2023，3，1： | 0 |
| 13 | Influence of permeability anisotropy of seepage flow on the tunnel face stability显示文摘This paper focuses on the influence of permeability anisotropy of seepage flow on the face stability for a shied tunnel.An analytical model has been proposed to present the hydraulic head distribution around the tunnel face in the anisotropic ground,considering the difference of permeability coefficient in the horizontal direction and the vertical direction.The rationality of the proposed model is ver-ified by a series of numerical simulations.Then,an analytical model of face stability for a tunnel under the anisotropic seepage has been established based on the limit analysis upper bound method.Comparisons of the analytical solutions and the numerical simulations are conducted,and the limit support pressure of the two methods is consistent.The effect of permeability anisotropy and water pressure on the stability of the tunnel face is analyzed through the three-dimensional analytical solution.Anisotropy of permeability has a significant impact on the stability of the tunnel face,and its impact gradually decreases.It can also be found that the water pressure coefficient of the tunnel face has a significant effect on the limit support pressure and the failure area when the ratio of the horizontal permeability to the vertical permeability is large. | Qiguang Di Pengfei Li Mingju Zhang Jie Wu | 2023 | Underground Space2023，，1： | 0 |
| 14 | ON INADMISSIBILITY OF SOME USUAL ESTIMATORS OF LOSS INCURRED IN ESTIMATING ERROR VARIANCE显示文摘Under multivariant normal linear models, it is proved that usual loss estima-tors based on the uniformly minimum variance unbiased estimator and the best affinelyequivariant estimator of error variance are inadmissible with squared error loss. | WU Qiguang Institute of Systems Science, Academia Sinica, Beijing 100080, China | 1993 | Systems Science and Mathematical Sciences1993，6，2： | 0 |
| 15 | Admissibilities of linear estimator in a class of linear models with a multivariate t error variable显示文摘This paper discusses admissibilities of estimators in a class of linear models,which include the following common models:the univariate and multivariate linear models,the growth curve model,the extended growth curve model,the seemingly unrelated regression equations,the variance components model,and so on.It is proved that admissible estimators of functions of the regression coefficient β in the class of linear models with multivariate t error terms,called as Model II,are also ones in the case that error terms have multivariate normal distribution under a strictly convex loss function or a matrix loss function.It is also proved under Model II that the usual estimators of β are admissible for p 2 with a quadratic loss function,and are admissible for any p with a matrix loss function,where p is the dimension of β. | YANG GuoQing 1 & WU QiGuang 2 1 Department of Mathematics,Tongji University,Shanghai 200092,China 2 Institute of Systems Science,Academy of Mathematics and Systems Science,Chinese Academy of Sciences,Beijing 100190,China | 2010 | Science China Mathematics2010，53，8： | 0 |
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