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144篇 您的检索式：作者名="WINTER E A"

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	题名	作者	年代	出处	被引量
1	Schistosoma mansoni proteins attenuate gastrointestinal motility disturbances during experimental colitis in mice显示文摘AIM:To investigate the therapeutic effect of Schistosoma mansoni(S.mansoni) soluble worm proteins on gastrointestinal motility disturbances during experimental colitis in mice. METHODS:Colitis was induced by intrarectal injection of trinitrobenzene sulphate(TNBS) and 6 h later,mice were treated ip with S.mansoni proteins.Experiments were performed 5 d after TNBS injection.Inflammationwas quantified using validated inflammation parameters. Gastric emptying and geometric center were measured to assess in vivo gastrointestinal motility.Peristaltic activity of distal colonic segments was studied in vitro using a modified Trendelenburg set-up.Cytokine profiles of T-lymphocytes isolated from the colon were determined by real time reverse transcriptase-polymerase chain reaction. RESULTS:Intracolonic injection of TNBS caused severe colitis.Treatment with S.mansoni proteins significantly ameliorated colonic inflammation after 5 d.TNBS did not affect gastric emptying but significantly decreased the geometric center and impaired colonic peristaltic activity 5 d after the induction of colitis.Treatment with S.mansoni proteins ameliorated these in vivo and in vitro motility disturbances.In addition,TNBS injection caused a downregulation of effector T cell cytokines after 5 d,whereas a S.mansoni protein effect was no longer observed at this time point. CONCLUSION:Treatment with S.mansoni proteins attenuated intestinal inflammation and ameliorated motility disturbances during murine experimental colitis.	Nathalie E Ruyssers Benedicte Y De Winter Joris G De Man Natacha D Ruyssers Ann J Van Gils Alex Loukas Mark S Pearson Joel V Weinstock Paul A Pelckmans Tom G Moreels	2010	World Journal of Gastroenterology2010，16，6：	11
2	Three-dimensional wave instability near a critical layer显示文摘	Winters K B D' asaro E A	1994	Joumal of Fluid Mechanics1994，272，：	1
3	Urban heat island effect analysis for San Juan, Puerto Rico 显示文摘	Velazquez Lozada A Gonzalez J E Winter A	2006	Atmospheric Environment2006，40，：	1
4	Reconstruction after Surgical Treatment of Head and Neck Cancer:Surgical and Prosthetic Possibilities 显示文摘	Schulten E A Winters H A Koch A E	2008	Ned Tijdschr Tandheelkd2008，115，4：	1
5	Photochemical generation of nitrenium ions from protonated 1,1- diarylhydrazines 显示文摘	Winter A H Thomas S L Falvey D E	2004	Org Lett2004，6，25：	1
6	Adjusting ath- letes~body mass index to better reflect adiposity in epidemio- logical research显示文摘	NEVILL A M WINTER E M WATTS A S	2010	J Sports Sci2010，28，：	1
7	Exogenously acquired Clostridium septicum gas gangrene-a case report 显示文摘	Winter E Dommke A Bonger BS	1998	Swiss Surg1998，，6：	1
8	Structural and functional adaptation following jejunal resection in rabbits effect of epidermal growth factor显示文摘	Winter M Shun A	1994	Gasteroeuterology1994，107，1：	1
9	Immunoglobulin class response to canine distemper virus in gnotobiotic dogs显示文摘	Winters K A Mathes L E Krakowka S	1983	Vet Immunol Immunopathol1983，5，2：	1
10	An integratedchemical biology approach identifies specific vulnerabili-ty of Ewing's sarcoma to combined inhibition of Aurorakinases A and B显示文摘	Winter G E Rix U Lissat A	2011	Mol Cancer Ther2011，10，10：	1
11	Defming the chronic impacts of atenolol on embryo - larval de?velopment and reproduction in the fathead minnow (Pimephales promelas)显示文摘	Winter MJ Lillicrap A D CaunterJ E	2008	Aquatic Toxicology2008，86，3：	1
12	Prognostic significance of BCL-6 protein expression in DLBCL treated with CHOP or R-CHOP:a prospective correlative study显示文摘	Winter J N Weller E A Horning S J	2006	Blood2006，107，11：	1
13	Premature induction of hypertrophy during in vitro chondrogenesis of human mesenchymal stem cells correlates with calcification and vascular invasion after ectopic transplantation in SCID mice显示文摘	Pelttari K Winter A Steck E	2006	Arthritis Rheum2006，54，：	1
14	Coordination and learning behavior in large groups with asymmetric players显示文摘	Rapoport A Seale D Winter E	2002	Cames and Economic Behavior2002，39，2：	1
15	Making antibodies by phage display technology显示文摘	Griffiths A D Hawkins R E	1994	Annu Rev Immunol1994，12，：	1
16	Natural product synthesis and vitamin B12 显示文摘	Eschenmoser A Winter C E	1977	Science1977，196，：	1
17	Balance recovery from medio-lateral perturbations of the upper body during standing 显示文摘	Rietdyk S Patla A E Winter D A	1999	J of Biomechanics1999，32，：	1
18	Serial monitoring of circu- lating tumor DNA in patients with primary breast cancer for de- tection of occult metastatic disease 显示文摘	Olsson E Winter C George A	2015	EMBO Mol Med2015，7，8：	1
19	Calcium acetate versus calcium carbonate as oral phosphate binder in pediatric and adolescent hemodialysis patients显示文摘	WALLOT M BONZEL K E WINTER A	1996	Pediatr Nephrol1996，，10：	1
20	Carrageenin-in- duced edema in hind paw of the rat as an assay for antiin- fiammatory drugs 显示文摘	WINTER C A RISLEY E A NUSS G W	1962	Pro Soc Exp Biol Med1962，111，：	1

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