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237篇 您的检索式：作者名="WINTER D A"

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	题名	作者	年代	出处	被引量
1	Schistosoma mansoni proteins attenuate gastrointestinal motility disturbances during experimental colitis in mice显示文摘AIM:To investigate the therapeutic effect of Schistosoma mansoni(S.mansoni) soluble worm proteins on gastrointestinal motility disturbances during experimental colitis in mice. METHODS:Colitis was induced by intrarectal injection of trinitrobenzene sulphate(TNBS) and 6 h later,mice were treated ip with S.mansoni proteins.Experiments were performed 5 d after TNBS injection.Inflammationwas quantified using validated inflammation parameters. Gastric emptying and geometric center were measured to assess in vivo gastrointestinal motility.Peristaltic activity of distal colonic segments was studied in vitro using a modified Trendelenburg set-up.Cytokine profiles of T-lymphocytes isolated from the colon were determined by real time reverse transcriptase-polymerase chain reaction. RESULTS:Intracolonic injection of TNBS caused severe colitis.Treatment with S.mansoni proteins significantly ameliorated colonic inflammation after 5 d.TNBS did not affect gastric emptying but significantly decreased the geometric center and impaired colonic peristaltic activity 5 d after the induction of colitis.Treatment with S.mansoni proteins ameliorated these in vivo and in vitro motility disturbances.In addition,TNBS injection caused a downregulation of effector T cell cytokines after 5 d,whereas a S.mansoni protein effect was no longer observed at this time point. CONCLUSION:Treatment with S.mansoni proteins attenuated intestinal inflammation and ameliorated motility disturbances during murine experimental colitis.	Nathalie E Ruyssers Benedicte Y De Winter Joris G De Man Natacha D Ruyssers Ann J Van Gils Alex Loukas Mark S Pearson Joel V Weinstock Paul A Pelckmans Tom G Moreels	2010	World Journal of Gastroenterology2010，16，6：	11
2	Soil microarthropods in longterm no-tillage and conventional corn production显示文摘	Winter J P Voroney R P Ainsworth D A	1990	Canadian Journal of Soil Science1990，70，：	1
3	Three-dimensional wave instability near a critical layer显示文摘	Winters K B D' asaro E A	1994	Joumal of Fluid Mechanics1994，272，：	1
4	Kinetic analysis of the lower limbsduring walking:What information can be gained from athree-dimensional model显示文摘	Eng J J Winter D A	1995	Biomech1995，28，6：	1
5	Thrombomodulin expression in colorectal carcinoma is protective and correlates with survival显示文摘	HANLY A M REDMOND M WINTER D C	2006	Br J Cancer2006，94，9：	1
6	Photochemical generation of nitrenium ions from protonated 1,1- diarylhydrazines 显示文摘	Winter A H Thomas S L Falvey D E	2004	Org Lett2004，6，25：	1
7	The selection of fusion levels in thoracic idiopathic seoliosis显示文摘	King H A Moe J H Bradford D S Winter R B	1983	J Bone Joint Surg Am1983，65，：	1
8	Stable hydrogen and oxygen isotope ratios of bottled waters of the world显示文摘	Bowen G J Winter D A Spero H J	2005	Rapid communications in mass spectrometry2005，19，23：	1
9	A two-part,viscoelastic footmodel for use in gait simulations 显示文摘	Gilchrist L A Winter D A	1996	Biomech1996，29，6：	1
10	Mechanical energy analyses of the human during load carriage on a treadmill 显示文摘	Pierrynowsi M R Norman R W Winter D A	1981	Ergonomics1981，24，1：	1
11	RBC alloantibody specificity and antigen potency in Olmsted County,Minnesota显示文摘	WINTERS J L PINEDA A A GORDEN L D	2001	Transfusion2001，41，：	1
12	Molecular MR imaging of melanoma angiogenesis with alphanubeta3- targeted paramagnetic nanoparticles显示文摘	Schmieder A H Winter P M Caruthers S D	2005	Magn Reson Med2005，53，3：	1
13	Trajectory of thebody COG and COP during initiation and termination of gait显示文摘	J1AN Y WINTER D A ISHAC M G	1993	Gait Posture1993，1，1：	1
14	Physical properties and rock physics models of sediment containing natural and laboratory-formed methane gas hydrate显示文摘	Winters W J Pecher I A Waite W F Mason D H		0，，8：	1
15	Phage antibodies: filamentous phage displaying anti-body variable domains显示文摘	Mccafferty J Griffiths A D Winter G	1990	Nature1990，348，：	1
16	Human balance and posture control during standing and walking显示文摘	D A WINTER PhD PENG	1995	Gait Posture1995，，3：	1
17	Cartilage-like gene expression in differentiated human stem cell spheroids:a comparison of bone marrowderived an addipose tissue-derived stromal cells显示文摘	Winter A Breit S Parsch D	2003	Arthritis Rheum2003，48，2：	1
18	Methane gas hydrate effect on sediment acoustic and strength properties显示文摘	Winters W J Waite W F Mason D H Gilbert L Y Pecher I A		0，，1：	1
19	Cartilage-like gene expression in differential human stem cell spheriods:a comparison of bone marrow-derived and adipose tissue-derived stromal cells显示文摘	Winter A Breit S Parsch D	2003	ArthritisRheum2003，48，：	1
20	Human balance and posture control during standing and walking 显示文摘	Winter D A	1995	Gait and Posture1995，3，：	1

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