|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | Seven Things We Think We Know about Auxin Transport显示文摘植物激素植物生长素的极的运输和最大值调整的局部性的植物生长素的建立胚胎的开发,干细胞维护,根和射击建筑学,和回归线生长回答。过去的十年被戏剧的进步在阐明的努力标记植物生长素运输由调整的复杂机制种生长。作为植物生长素的理解,运输规定逐渐地被详细描述,这个过程在某些方面涉及几乎所有植物生长和环境回答,变得清楚。然而,我们仍然关于这基本规章的机制的一些基本方面缺乏信息。在这评论,我们在场我们知道什么(或我们认为什么我们知道) 并且我们什么不知道大约七个调整植物生长素的过程。我们在主要、侧面的根,向光性,分叉的射击,叶扩大,和脉络在 gravitropism 讨论植物生长素运输的角色。我们也在根尖端,植物生长素运输过程的 flavonoid 调整,和植物生长素 transporters 的 translational 以后规定的突出的方面讨论植物生长素倒流 / 喷泉模型。这讨论没打算彻底,但是加亮在哪个通常认为假设要求更真实的确认的区域。 | Wendy Ann Peer Joshua J. Blakeslee Haibing Yang Angus S. Murphy | 2011 | Molecular Plant2011，4，3： | 29 |
| 3 | SPIRIT 2013声明:定义临床研究方案的标准条目显示文摘临床研究方案是临床研究设计、实行、报告和评价的基础。然而,临床研究方案及现存的临床研究方案指引在内容和质量上差异很大。本文描述了《规范临床研究方案内容》(Standard Protocol Items:Recommendations for Interventional Trials 2013 ),简称SPIRIT2013声明,一个临床研究方案必须报告的条目指引的系统建立和范围。 | An-Wen Chan Jennifer M.Tetzlaff Douglas G.Altman Andreas Laupacis Peter C.GΦtzsche Karmela Krleza-Jeri AsbjΦrn Hróbjartsson Howard Mann Kay Dickersin Jesse A.Berlin Caroline J.Doré Wendy R.Parulekar William S.M.Summerskill Trish Groves Kenneth F.Schulz Harold C.Sox Frank W.Rockhold Drummond Rennie David Moher 钟丽丹 郑颂华 吴泰相 李幼平 商洪才 张伯礼 唐旭东 吕爱平 卞兆祥 | 2013 | 中国循证医学杂志2013，13，12： | 23 |
| 4 | Exploring alternative treatments for Helicobacter pylori infection显示文摘Helicobacter pylori(H. pylori) is a successful pathogen that can persist in the stomach of an infected person for their entire life. It provokes chronic gastric inflammation that leads to the development of serious gastric diseases such as peptic ulcers, gastric cancer and Mucosa associated lymphoid tissue lymphoma. It is known that these ailments can be avoided if the infection by the bacteria can be prevented or eradicated. Currently, numerous antibiotic-based therapies are available. However, these therapies have several inherent problems, including the appearance of resistance to the antibiotics used and associated adverse effects, the risk of re-infection and the high cost of antibiotic therapy. The delay in developing a vaccine to prevent or eradicate the infection has furthered research into new therapeutic approaches. This review summarises the most relevant recent studies on vaccine development and new treatments using natural resources such as plants, probiotics and nutraceuticals. In addition, novel alternatives based on microorganisms, peptides, polysaccharides, and intragastric violet light irradiation are presented. Alternative therapies have not been effective in eradicating the bacteria but have been shown to maintain low bacterial levels. Nevertheless, some of them are useful in preventing the adverse effects of antibiotics, modulating the immune response, gastroprotection, and the general promotion of health. Therefore, those agents can be used as adjuvants of allopathic anti-H. pylori eradication therapy. | Guadalupe Ayala Wendy Itzel Escobedo-Hinojosa Carlos Felipe de la Cruz-Herrera Irma Romero | 2014 | World Journal of Gastroenterology2014，20，6： | 16 |
| 5 | Accurate diagnosis of prenatal cleft lip/palate by understanding the embryology显示文摘Cleft lip with or without cleft palate(CP) is one of the most common congenital malformations. Ultrasonographers involved in the routine 20-wk ultrasound screening could encounter these malformations. The face and palate develop in a very characteristic way. For ultrasonographers involved in screening these patients it is crucial to have a thorough understanding of the embryology of the face. This could help them to make a more accurate diagnosis and save time during the ultrasound. Subsequently, the current postnatal classification will be discussed to facilitate the communication with the CP teams. | Bram Smarius Charlotte Loozen Wendy Manten Mireille Bekker Lou Pistorius Corstiaan Breugem | 2017 | World Journal of Methodology2017，7，3： | 15 |
| 6 | 基于逻辑回归模型的泥石流易发性评价与检验:以金沙江上游奔子栏—昌波河段为例显示文摘基于地理信息系统(Arc GIS10.0)平台和小流域单元,采用逻辑回归(LR)模型对金沙江上游(奔子栏—昌波河段)干热河谷区进行泥石流易发性评价,并对预测结果进行总体检验与随机个案检验。评价与检验结果表明,得到的最优指标组合下LR评价模型的AUC值为82.7%;预测的极高易发区、高易发区面积合占全区面积的35.98%,实发泥石流面积占泥石流总面积的65.03%;在个案检验中,位于各等级分区的检验组样本实发泥石流比例随着分区易发性等级降低,依次为91.7%(极高)、75.0%(高)、36.4%(中等)、16.7%(低)、0(极低),表明评价效果良好。研究区泥石流集中发育于金沙江沿岸的东北部、中部和西南部,主导性的评价指标依次为距主干道路距离、岩性、距断裂带距离、雨季月平均降雨量。人类活动与季节性降雨为研究区干热河谷泥石流的主要诱发条件。基于逻辑回归模型的泥石流易发性评价方法提高了泥石流发生可能性的预测精度,可为干热河谷区泥石流预测预警和防治提供参考依据。 | 吴赛儿 陈剑 ZHOU Wendy 高玉欣 徐能雄 | 2018 | 现代地质2018，32，3： | 14 |
| 7 | When water meets iron at Earth's core-mantle boundary显示文摘Hydrous minerals in subducted crust can transport large amounts of water into Earth's deep mantle. Our laboratory experiments revealed the surprising pressure-induced chemistry that, when water meets iron at the core-mantle boundary, they react to form an interlayer with an extremely oxygen-rich form of iron, iron dioxide, together with iron hydride. Hydrogen in the layer will escape upon further heating and rise to the crust, sustaining the water cycle. With water supplied by the subducting slabs meeting the nearly inexhaustible iron source in the core, an oxygen-rich layer would cumulate and thicken, leading to major global consequences in our planet. The seismic signature of the D″ layer may echo the chemical complexity of this layer. Over the course of geological time, the enormous oxygen reservoir accumulating between the mantle and core may have eventually reached a critical eruption point. Very large-scale oxygen eruptions could possibly cause major activities in the mantle convection and leave evidence such as the rifting of supercontinents and the Great Oxidation Event. | Ho-Kwang Mao Qingyang Hu Liuxiang Yang Jin Liu Duck Young Kim Yue Meng Li Zhang Vitali B.Prakapenka Wenge Yang Wendy L.Mao | 2017 | National Science Review2017，4，6： | 14 |
| 8 | 医务人员职业倦怠与工作满意度现状调查显示文摘目的调查医务人员职业倦怠与工作满意度情况。方法采用随机数字表法选取佛山市公立医院医务人员1 620名,采用职业生活质量量表(Pro QOL)、明尼苏达工作满意度问卷短式量表(MSQ)、主观幸福感量表(SHS)进行评定。结果共收集有效问卷1 423份;30≤年龄<40岁的医务人员职业倦怠评分高于20≤年龄<30岁者[(28.29±5.38)分vs.(27.27±5.20)分,t=-1.02,P=0.014],医生职业倦怠评分高于护士[(28.34±5.29)分vs.(27.34±5.16)分,t=-1.00,P=0.009],中级职称医务人员职业倦怠评分高于初级职称者[(28.28±5.16)分vs.(27.36±5.25)分,t=0.92,P=0.020],硕士学历者职业倦怠评分高于专科学历者[(28.49±4.96)分vs.(27.08±5.30)分,t=1.42,P=0.043],精神专科医院及口腔医院的医务人员职业倦怠评分低于其他医院医务人员[(25.39±5.00)分vs.(26.03±4.22)分,F=11.62,P<0.01],而工作满意度评分[(72.98±9.52)分vs.(71.18±8.07)分,F=7.31,P<0.01]和主观幸福感评分[(20.02±3.94)分vs.(20.33±3.67)分,F=5.65,P<0.01)]均高于其他医院。结论 30≤年龄<40岁、医生、中级职称、硕士学历的医务人员职业倦怠水平较高,精神专科医院及口腔医院医务人员职业倦怠水平较低且工作满意度和主观幸福感较高。 | 谢国军 Wendy Li 徐彩霞 李晓玲 徐国洪 | 2017 | 四川精神卫生2017，30，6： | 13 |
| 9 | 大豆蛋白体外酶解物中血管紧张素转化酶抑制剂活性肽研究显示文摘目的:体外模仿部分胃肠道消化酶解过程,考察大豆蛋白酶解消化能否产生血管紧张素转化酶抑制剂(ACEI)活性肽及其活性状况,以揭示大豆蛋白体内消化酶解与ACEI的活性关系。方法:模拟人体胃肠道消化过程,以胃蛋白酶结合胰蛋白酶,相继酶解大豆分离蛋白(SPI),经色谱分离,动态检测不同阶段ACEI肽片段及其活性大小。结果:胃蛋白酶酶解过程前20min内,酶解液ACEI活性达到最高点,随后在胰蛋白酶酶解阶段其抑制活性下降。180min后的酶解产物,其半抑制活性浓度IC50值为0.28±0.06 mg/ml。同时,未经酶解的SPI液在0.73mg/ml时无ACEI活性。SPI酶解液经各种色谱分离后的组分,其IC50值从0.13±0.03到0.93±0.08 mg/ml。低分子量和伴有疏水性基团的肽类最具ACE抑制活性。结论:体外模仿胃肠消化过程使用胃蛋白酶和胰蛋白酶酶解SPI可产生不同ACEI活性的肽片段,说明人体正常摄食消化大豆蛋白可产生血管紧张素转化酶抑制剂活性肽。 | 刘志伟 刘秀梅 郑梦云 WENDY LO EUNICE LI-CHAN | 2007 | 营养学报2007，29，1： | 13 |
| 10 | Current and future therapies for inherited cholestatic liver diseases显示文摘Familial intrahepatic cholestasis(FIC) comprises a group of rare cholestatic liver diseases associated with canalicular transport defects resulting predominantly from mutations in ATP8B1, ABCB11 and ABCB4. Phe-notypes range from benign recurrent intrahepatic cholestasis(BRIC), associated with recurrent cholestatic attacks, to progressive FIC(PFIC). Patients often suffer from severe pruritus and eventually progressive cholestasis results in liver failure. Currently, first-line treatment includes ursodeoxycholic acid in patients with ABCB4 deficiency(PFIC3) and partial biliary diversion in patients with ATP8B1 or ABCB11 deficiency(PFIC1 and PFIC2). When treatment fails, liver transplantation is needed which is associated with complications like rejection, post-transplant hepatic steatosis and recurrence of disease. Therefore, the need for more and better therapies for this group of chronic diseases remains. Here, we discuss new symptomatic treatment options like total biliary diversion, pharmacological diversion of bile acids and hepatocyte transplantation. Furthermore, we focus on emerging mutation-targeted therapeutic strategies, providing an outlook for future personalized treatment for inherited cholestatic liver diseases. | Wendy L van der Woerd Roderick HJ Houwen Stan FJ van de Graaf | 2017 | World Journal of Gastroenterology2017，23，5： | 11 |
| 11 | 硼污染的个人暴露剂量及其代谢的研究显示文摘以62名处于不同生活、工作环境下的人群为对象,研究了其通过空气粉尘、饭菜和饮水的日硼暴露剂量及通过尿液、粪便的代谢状况.结果表明,从事硼作业的53名工人日硼暴露均值11.8mg/d,是对照人群(1.52mg/d)的7.8倍;通过尿液代谢的硼占总代谢量的94%以上,且班后尿硼与24h全尿硼浓度的相关系数为0.952,班后尿样可代替全尿并反映硼的代谢水平;下班后尿硼浓度与日硼暴露剂量显著相关.多元线性回归可以反映不同暴露途径对尿硼水平的贡献,方程拟合度为43.0%,与实测值的平均相对偏差为23.6%. | 邢小茹 魏复盛 吴国平 荀琳 Wendie A Robbins 王春利 魏春 姜欣 葛宏斌 | 2005 | 中国环境科学2005，25，3： | 10 |
| 12 | A study on the Dushiling tungsten-copper deposit in the Miao'ershan-Yuechengling area, Northern Guangxi, China:Implications for variations in the mineralization of multi-aged composite granite plutons显示文摘The polymetallic Dushiling W-Cu deposit is a large, altered, skarn-type deposit, located in the northeastern part of the Miao'ershan-Yuechengling pluton, China. Two types of granite have been identified in the deposit: a medium-grained porphyritic biotite granite, and a medium- to fine-grained biotite granite. Both are spatially and temporally related to ore bodies, suggesting they may be the source of mineralization in the deposit. A medium- to fine-grained porphyritic biotite granite is exposed at the surface in the region of mineralization. U-Pb dating of zircons yielded magmatic ages of 423 Ma for the medium-grained porphyritic biotite granite and 421 Ma for the medium- to fine-grained porphyritic biotite granite, while a younger age(217 Ma) obtained for surface samples indicates later diagenesis. Thus, magmatism occurred during the Caledonian and Indosinian, respectively. The petrological and geochemical characteristics of the two Caledonian granites show that both are calc-alkaline and peraluminous.They are moderately enriched in Cs, Rb, U, and REE, and strongly depleted in Sr,Ba,P,and Ti; they show similar REE behavior,including negative Eu anomalies. These geochemical similarities suggest that the two granites were derived from the same source,although they were emplaced during different stages of the evolution of the magma. Furthermore, the granites are associated with mineralization, suggesting they were the source of mineralization in the Dushiling W-Cu deposit. Sm-Nd ages of scheelite from the Dushiling W-Cu deposit indicate that metallogenesis occurred at 417±35 Ma, while the two types of titanite, intergrown with scheelite, yield U-Pb ages of 423–425 Ma(in altered granite sample) and 218 Ma(in skarn sample). These ages place the main mineralization event in the late Caledonian, and later magmatic-hydrothermal activity occurred in the Indosinian. The ages obtained for the Dushiling W-Cu deposit in the western Nanling Range, northern Yuechengling, together with the occurrence and ages of the Niutangjie W deposit in southern Yuechengling, provide insight into the process of ore concentration during the Caledonian and Indosinian. | CHEN WenDi ZHANG WenLan WANG RuCheng CHU ZhuYin XIAO Rong ZHANG Di CHE XuDong | 2016 | Science China Earth Sciences2016，59，11： | 10 |
| 13 | 美国1961~2000年氮使用量的变化及未来趋势预测显示文摘从1961~1997年,因人类活动而输入到美国的氮翻了一番,特别是在上个世纪60年代和70年代,其增长量最大。尽管无机氮肥的使用量增长最大,但矿物燃料燃烧所造成的NO_x排放,也有明显的增加。1961年,美国农业生产系统中的生物固氮量是活性氮的最大来源;到了1997年,尽管生物固氮量也有增加,但相比而言,无机氮肥的使用和NO_x的排放增加得更快,成为两个最大的氮源。1961~1997年,在输入到美国的活性氮中,有2/3发生了脱氮反应或者是被贮存在土壤与生物群落之中,有1/3输出到境外。在输出到境外的这部分氮中,通过河流流到海洋中的分量最大,其次是通过粮食和饲料出口而到其它国家以及通过大气平流传输到了海洋中。动物性蛋白的消费是美国农业系统中氮使用的主要驱动因子,如果饮食方式或农业生产方式不发生改变,在来来30年的时间里,美国肥料的使用量将继续增长,流向海洋中的氮通量将可能再增长30%,但也有可能出现下降。 | Robert W.Howarth Elizabeth W.Boyer Wendy J.Pabich James N.Galloway 闵庆文 | 2002 | AMBIO-人类环境杂志2002，31，2： | 9 |
| 14 | 儿童游戏的权利--世界范围内游戏在儿童生活中重要性的考察(连载之一)显示文摘本文系统考察世界范围内游戏在儿童生活中重要性,将儿童的游戏权看做1989年联合国《儿童权利公约》(CRC)第31条中的一个独立的权利,旨在为世界范围内和整个联合国《儿童权利公约》框架内探究'儿童的游戏权'提供理论基础,并提出人们为何要承认、尊重儿童游戏权,并阐明将游戏提升为一种儿童权利的理论依据,主张全面深刻理解儿童游戏权利的丰富内涵,特别是作为自我保护方式及作为参与日常生活方法的游戏的社会价值,应积极创设提供儿童游戏发生的条件,努力推进实现儿童的游戏权利。 | Stuart Lester Wendy Russell 周桂勋 | 2018 | 陕西学前师范学院学报2018，34，1： | 9 |
| 15 | MoodGYM网络认知行为治疗对护理人员焦虑抑郁情绪的干预研究显示文摘目的评估MoodGYM网络认知行为治疗对护理人员焦虑、抑郁情绪的疗效。方法选取180例具有焦虑或者抑郁或者兼有焦虑抑郁情绪的护理人员,随机分成3组,每组各60例,分别使用MoodGYM(MoodGYM组)和健康教育(健教组)进行为期2个月的干预(每周1次,每次30~45分钟),另一组作为对照组。干预前后分别采用抑郁焦虑压力量表(depression anxiety stress scale 21,DASS-21)、明尼苏达满意度问卷(Minnesota satisfaction questionnaire,MSQ)和主观幸福感量表(subjective happiness scale,SHS)进行心理评估。结果与干预前相比,干预后MoodGYM组焦虑因子分[(16.76±7.61)分,(9.67±5.78)分,t=21.339,P<0.01]、抑郁因子分[(13.86±7.60)分,(10.91±7.12)分,t=16.716,P<0.01]下降,MSQ工作满意度[(65.11±11.12)分,(67.97±11.10)分,t=-16.400,P<0.01]、SHS主观幸福感[(17.67±4.59)分,(21.83±3.53)分,t=-20.221,P<0.01]升高;健教组焦虑[(15.81±8.24)分,(12.45±7.68)分,t=17.566,P<0.01]、抑郁因子分[(12.44±8.23)分,(12.09±7.95)分,t=3.934,P<0.01]下降,工作满意度[(67.37±9.76)分,(68.91±9.67)分,t=-4.474,P<0.01]、主观幸福感分值[(17.93±3.80)分,(19.85±3.96)分,t=-14.897,P<0.01]升高;干预后,MoodGYM组在改善焦虑、抑郁、提升工作满意度和主观幸福感方面的效应较健教组更明显(均P<0.01)。结论MoodGYM干预能缓解护理人员的焦虑、抑郁情绪,提升护理人员的工作满意度与主观幸福感。 | 谢国军 Wendy Li 贾福军 | 2019 | 中华行为医学与脑科学杂志2019，28，5： | 9 |
| 16 | 职业精神和医患关系显示文摘通过调查发现,外科医生在提供做决策的信息的问题上执行得较好;有些医生无论错误多么严重也不会把医疗错误披露出来;但是能够公开医生的经济奖励,这样医生的信任不但没有被损害,相反医生和医生团体的信任和忠诚却增强了。从知情决策、医疗错误的披露和利益冲突三个方面展示职业精神对医患关系产生的影响,并为职业精神的发展提供了新视角。 | Wendy Levinson | 2007 | 医学与哲学(A)2007，28，3： | 9 |
| 17 | 超级热凝胶的甲基纤维素在食品中的应用显示文摘甲基纤维素以天然纤维素为原料,以甲氧基取代纤维素中的无水葡萄糖单元上羟基的形成的一类非离子型纤维素醚,具有保水、增稠、乳化、成膜、适应pH范围广及表面活性等功能,其最为特殊的是热可逆凝胶性,即其水溶液在加热情况下形成凝胶,当冷却时又变回溶液,广泛应用于烘焙食品、油炸食品、甜点、调味酱、汤、饮料、香精和糖果中。甲基纤维素中的超级凝胶具有比常规甲基纤维素热凝胶三倍以上的凝胶强度,具备了超强的黏附性能,保水和保型性能。它可以使重组成型类食品在加热时和加热后更长时间地保持食品所需的结实质构和多汁的口感。其典型应用有速冻食品、素食制品、重组肉、鱼和海鲜制品和低脂香肠。 | 颜正勇 孙子重 Wendy Soo Cecelia Kong Michiel Van Genugten | 2012 | 中国食品添加剂2012，，S1： | 8 |
| 18 | 硼作业工人配偶妊娠结局的初步研究显示文摘目的 研究硼暴露对作业工人配偶生殖健康的影响。方法 选择硼暴露组和对照组作为研究对象,进行标准问卷调查,建立相关数据库,通过χ2 检验、多元非条件Logistic回归进行分析。结果 暴露组的自然流产率和不能顺利受孕率均高于对照组。暴露组后代子女性别比低于对照组以及全国和辽宁省出生婴儿性别比。结论 硼暴露对硼作业工人配偶的妊娠结局可能有不良影响。 | 刘平 王春利 胡俊峰 Lin Xun Wendie A Robbins 吴国平 魏复盛 | 2005 | 中国公共卫生2005，21，5： | 8 |
| 19 | Neuroimaging the brain-gut axis in patients with irritable bowel syndrome显示文摘AIM:To summarize and synthesize current literature on neuroimaging the brain-gut axis in patients with irritable bowel syndrome(IBS).METHODS:A database search for relevant literature was conducted using Pub Med,Scopus and Embase in February 2015.Date filters were applied from the year2009 and onward,and studies were limited to those written in the English language and those performed upon human subjects.The initial search yielded 797articles,out of which 38 were pulled for full text review and 27 were included for study analysis.Investigations were reviewed to determine study design,methodology and results,and data points were placed in tabular format to facilitate analysis of study findings across disparate investigations.RESULTS:Analysis of study data resulted in the abstraction of four key themes:Neurohormonal differences,anatomic measurements of brain structure and connectivity,differences in functional responsiveness of the brain during rectal distention,and confounding/correlating patient factors.Studies in this review noted alterations of glutamate in the left hippocampus(HIPP),commonalities across IBS subjects in terms of brain oscillation patterns,cortical thickness/gray matter volume differences,and neuroanatomical regions withincreased activation in patients with IBS:Anterio cingulate cortex,mid cingulate cortex,amygdala anterior insula,posterior insula and prefrontal cortex.A striking finding among interventions was the substantia influence that patient variables(e.g.,sex,psychologica and disease related factors)had upon the identification of neuroanatomical differences in structure and con nectivity.CONCLUSION:The field of neuroimaging can provide insight into underlying physiological differences that distinguish patients with IBS from a healthy population. | Kristen R Weaver Lee Anne B Sherwin Brian Walitt Gail D'Eramo Melkus Wendy A Henderson | 2016 | World Journal of Gastrointestinal Pharmacology and Therapeutics2016，7，2： | 8 |
| 20 | 护理领导力培养的研究进展显示文摘护理领导力不仅是领导者应具备的素质,还是护理实践的重要组成部分,护理领导力培养是现代医疗体系不可或缺的一环。目前国内护理领导力起步较晚,缺乏规范的护理领导力培训体系,对护理领导力的研究和关注较为薄弱。该文旨在对护理领导力培训的形式、内容、方法、评价和效果进行分析总结,以期为国内护理领导力的培养提供参考。 | 许湘华 李旭英 Wendy Gifford 谌永毅 | 2019 | 中华护理教育2019，16，11： | 8 |
您所在的机构暂未开通此部分的功能，请联系管理员