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| 1 | Diagnosis of Helicobacter pylori infection: Current options and developments显示文摘Accurate diagnosis of Helicobacter pylori(H. pylori) infection is a crucial part in the effective management of many gastroduodenal diseases. Several invasive and non-invasive diagnostic tests are available for the detection of H. pylori and each test has its usefulness and limitations in different clinical situations. Although none can be considered as a single gold standard in clinical practice,several techniques have been developed to give the more reliable results. Invasive tests are performed via endoscopic biopsy specimens and these tests include histology,culture,rapid urease test as well as molecular methods. Developments of endoscopic equipment also contribute to the real-time diagnosis of H. pylori during endoscopy. Urea breathingtest and stool antigen test are most widely used noninvasive tests,whereas serology is useful in screening and epidemiological studies. Molecular methods have been used in variable specimens other than gastric mucosa. More than detection of H. pylori infection,several tests are introduced into the evaluation of virulence factors and antibiotic sensitivity of H. pylori,as well as screening precancerous lesions and gastric cancer. The aim of this article is to review the current options and novel developments of diagnostic tests and their applications in different clinical conditions or for specific purposes. | Yao-Kuang Wang Fu-Chen Kuo Chung-Jung Liu Meng-Chieh Wu Hsiang-Yao Shih Sophie SW Wang Jeng-Yih Wu Chao-Hung Kuo Yao-Kang Huang Deng-Chyang Wu | 2015 | World Journal of Gastroenterology2015，21，40： | 66 |
| 2 | Dual specimens increase the diagnostic accuracy and reduce the reaction duration of rapid urease test显示文摘AIM:To evaluate the influence of multiple samplings during esophagogastr oduodenoscopy(EGD) on the accuracy of the rapid urease test,and the validity of newly developed rapid urease tests,HelicotecUT plus test and HelicotecUT test,CLO test and ProntoDry test.METHODS:A total of 355 patients undergoing EGD for dyspepsia were included.Their Helicobacter pylori(H.pylori) treatment status was either nave or eradicated.Six biopsy specimens from antrum and gastric body,respectively,were obtained during EGD.Single antral specimens and dual(antrum+body) specimens were compared.Infection status of H.pylori was evaluated by three different tests:culture,histology,and four different commercially available rapid urease tests(RUTs)-including the newly developed HelicotecUT plus test and HelicotecUT test,and established CLO test and ProntoDry test.H.pylori status was defined as positive when the culture was positive or if there were concordant positive results among histology,CLO test and ProntoDry test.RESULTS:When dual specimens were applied,sensitivity was enhanced and RUT reaction time was signif icantly reduced,regardless of their treatment status.Thirty minutes were enough to achieve an agreeable positive rate in all the RUTs.Both newly developed RUTs showed comparable sensitivity,specif icity and accuracy to the established RUTs,regardless of patient treatment status,RUT reaction duration,and EGD biopsy sites.CONCLUSION:Combination of antrum and body biopsy specimens greatly enhances the sensitivity of rapid urease test and reduces the reaction duration to 30 min. | Wen-Hung Hsu Sophie SW Wang Chiao-Yun Chen Ching-Wen Chang Jaw-Yuan Wang Yuan-Chieh Yang Deng-Chyang Wu Ming-Tsang Wu | 2010 | World Journal of Gastroenterology2010，16，23： | 13 |
| 3 | Low effect‐site concentration of propofol target‐controlled infusion reduces the risk of hypotension during endoscopy in a T aiwanese population显示文摘 | Wen‐Hung Hsu Sophie SW Wang Hsiang‐Yao Shih Meng‐Chieh Wu Yi‐Yu Chen Fu‐Chen Kuo Hui‐Ying Yang Shun‐Li Chiu Koung‐Shing Chu Kuang‐I Cheng Deng‐Chyang Wu I‐Cheng Lu | 2013 | Journal of Digestive Diseases2013，，3： | 3 |
| 4 | The Statistical Relation of Shear Velocity with Soil Properties显示文摘Shear velocity is an important index for evaluating soil dynamic properties of the site.In thispaper,the statistical relation of shear velocity with soil properties is set up by statistical analysis of shearvelocities and relevant soil properties measured in Tianjin and Shanghai.The obtained formula has somereferential value for the evaluation and classification of the site in offshore areas of China. | Gao, YL Yan, SW Wang, JY | 1998 | China Ocean Engineering1998，13，1： | 2 |
| 5 | Delayed cardioprotection of aged rat myocytes is associated with activation of mitogenactivated protein kinase 显示文摘 | Liu XH Wang SW Wu XD | 2000 | Chinese Medical Journal2000，113，1： | 2 |
| 6 | Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon ougrowth显示文摘 | Wang SW Mu X Bowers WJ | 2002 | Development2002，129，： | 1 |
| 7 | Time-intensity based volumetric flow measurements:an in vitro study显示文摘 | Li PC Yeh CK Wang SW | 2002 | Ultrasound Med Biol2002，28，3： | 1 |
| 8 | Effects of tamsulosin on lower uri-nary tract symptoms due to double-J stent:a prospective study显示文摘 | Wang CJ Huang SW Chang CH | 2009 | U-rol Int2009，83，1： | 1 |
| 9 | 显示文摘 | Fan YJ Wang SW Sun ZX | 2012 | Mater Chem Phys2012，134，1： | 1 |
| 10 | Enterovirus 71 infection of human dendritic cells显示文摘 | Lin YW Wang sw Tung YY | 2009 | Exp Biol Med2009，234，10： | 1 |
| 11 | MiR-23a-mediated inhibition of topoisomerase 1 expression potentiates cell response to etoposide in human hepatocellular carcinoma显示文摘 | Wang N Zhu M Tsao SW | 2013 | Mol Cancer2013，12，1： | 1 |
| 12 | Decreased tobacco-specific nitrosamines by microbial treatment with Bacillus amyloliquefaciens DA9 during the Air-Curing process of burley tobacco 显示文摘 | Wei XT Deng XW Cai DB Ji ZX Wang CJ Yu J Li JP and Chen SW | 2014 | J Agric Food Chem2014，62，12： | 1 |
| 13 | Doppler Ultrasoundguided Percutaneous Nephrolithotomy:A Prospective Randomized Study显示文摘 | Tzeng BC Wang CJ Huang SW | 2011 | Urology2011，78，3： | 1 |
| 14 | Inhibitory effect of digoxin on testosterone secretion through mechanisms involving decreases of cyclic AMP production and cytochrome P450scc activity in rat testicular interstitial ceils 显示文摘 | Lin H Wang SW Tsai SC | 1998 | BrJ Pharmacol1998，125，8： | 1 |
| 15 | Mediation of poly(ADP- ribose) polymerase-l-dependent cell death by apoptosis- inducing factor显示文摘 | YU SW WANG H POITRAS MF | 2002 | Science2002，297，： | 1 |
| 16 | Post-opertive radjotherapy in early stage careinoma of the uterine cervix:treatment results and prognostic factors显示文摘 | Yeh SA Leung SW Wang CJ | 1999 | Gynecol Oncotl1999，72，1： | 1 |
| 17 | TNF alpha concentrations and mRNA expressionare increased in preeclamptic placentas 显示文摘 | Wang Y Walsh SW | 1996 | J Reprod Immunol1996，32，： | 1 |
| 18 | Diminished type IK col- lagen promotes myofibroblast differentiation and increases scar deposition in cutaneous wound healing 显示文摘 | Volk SW Wang Y Mauldin EA | 2011 | Cells Tissues Organs2011，194，1： | 1 |
| 19 | Differential niche and Wnt requirements during acute myeloid leukemia progression 显示文摘 | Lane SW Wang YJ Lo Celso C | 2011 | Blood2011，118，10： | 1 |
| 20 | Examining the small world phenomenon in the patent citation network: a case Study of the radio frequency identification (RFID) network 显示文摘 | Hung SW Wang AP | 2010 | SCIENTOMETRICS2010，82，1： | 1 |
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