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您的检索式：作者名="Vinit Parmar"
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| 1 | Lepidium sativum Linn.种子的脱脂乙醇提取物体外自由基清除活性(英文)显示文摘AIM:The objective of the present study was to evaluate the antioxidant potential of the defatted ethanolic extract of the seeds of Lepidium Sativum Linn.METHODS:Different in vitro chemical assays viz.DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging,ABTS (2,2-azinobis-(3-ethylbenzothiazoline-6-sulphonate) radical scavenging,iron chelation,lipid peroxidation,super-oxide scavenging and non-enzymatic haemoglobin glycosylation assay were used.The total antioxidant capacity of the extract was determined spectrophotometrically by phosphomolybdic acid method.RESULT & CONCLUSION:The defatted lepidium seed extract showed significant free radical scavenging activity in ABTS and non-enzymatic glycosylation assays,and a moderate activity in all the other assays.IC50 of the extract in the DPPH,ABTS,iron chelation,lipid peroxidation and super oxide scavenging assays were found to be 171.13,38.64,128.94,71.39 and 206.09 μg·mL-1 respectively.The haemoglobin glycosylation assay of the extract showed a percentage scavenging of 46.60% and 74.88%,at 0.5 and 1.0 μg·mL-1,concentrations,respectively.Total antioxidant capacity of ethanolic extract of L.sativum (10 mg·mL-1) was found to be equivalent to 58.38 μg·mL-1 of ascorbic acid. | Annie Shirwaikar Bharatkumar Patel Yogesh Kamariya Vinit Parmar Saleemulla Khan | 2011 | 中国天然药物2011，9，6： | 1 |
| 2 | 印度Anisochilus carnosus(L.F.)Wall.的体外自由基清除活性(英文)显示文摘AIM:To evaluate in vitro anti-oxidant potential of methanolic and aqueous extract of Indian habitants Anisochilus carnosus (L.F.) wall.,which is an annual shrub belonging to the family Lamiaceae commonly known asmint family.METHODS:The present study describes the effects by DPPH,alkaline DMSO,scavenging of ferric ion,NO,H 2 O 2,ABTS models.Both extracts showed good free radical scavenging property which was calculated as IC 50.RESULTS:IC 50 of aqueous and methanolic extracts were found to be 7.09 and 5.77 μg·mL-1 for DPPH,8.14 and 13.29 μg·mL-1 for alkaline DMSO,27.16 and 31.25 μg·mL-1 for scavenging of ferric ion,13.82 and 26.94 μg·mL-1 for NO,13.82 and 26.94 μg·mL-1 for H 2 O 2,113.84 and 128.03 μg·mL-1 for ABTS,which were compared with Ascorbic acid (DPPH,scavenging of ferric ion,NO,ABTS) and rutin (alkaline DMSO,H 2 O 2).Total antioxidant capacity of the extract was found to be 213 and 172 μg·mL-1 ascorbic acid for methanolic and aqueous extracts respectively.CONCLUSION:A.carnosus leaf extracts exhibited potent free radical scavenging activity.The overall antioxidant activity is attributed to its polyphenolic and other phytochemical constituents.The findings suggest that A.carnosus leaves could be a potential source of natural antioxidant in preventing or slowing the progression of aging and age-associated oxidative stress-related degenerative diseases. | Jaykumar Bhagat Richard Lobo Vinit Parmar Mamatha Ballal | 2011 | 中国天然药物2011，9，6： | 1 |
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