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| 1 | Insulin sensitizers in treatment of nonalcoholic fatty liver disease:Systematic review显示文摘AIM: To summarize the evidence available for the clinical effectiveness of insulin sensitizers in the treatment of nonalcoholic fatty liver disease (NAFLD) systematically. METHODS: Relevant articles were located using computer-assisted searches of Medline (1966-March 2006), EMBASE (1988-March 2006), CINAHL (1982-March 2003), Educational Resource Information Center (1966-March 2006), Library, Information Science & Technology Abstracts (1967-March 2006), Cochrane Database of Systematic Reviews, Database of Abstracts of Reviews of Effects (1994-2006), dissertations in ProQuest and FirstSearch databases. Manual searches were made in the abstracts from meetings of the American Gastroenterological Association (1999-2006), and the American Association for the Study of Liver Diseases (2003-2005). Studies were retrieved using the following selection criteria: (1) clinical trials using insulin sensitizers in subjects with NAFLD, (2) adult patients, (3) published as full manuscripts or abstracts, and (4) English, Spanish, German, and French languages only. Data were abstracted independently by two reviewers following standardized procedures. A face-to- face comparison of data was conducted to ensure the completeness and reliability of the abstraction process. RESULTS: Nine studies were included, six using metformin and three using thiazolidinediones. Only two studies were placebo-controlled trials. The mediansample size for all studies was 18 subjects. In the placebo-controlled trials, metformin improved insulin resistance markers and liver function tests, but not histological scores. In the single-arm trials, metformin and thiazolidinediones improved insulin resistance markers and liver function tests, and beneficial histological changes were reported. There is limited high-quality information available from which to draw categorical conclusions about the clinical use of insulin sensitizers in NAFLD.CONCLUSION: Current information indicates that the use of insulin sensitizers in NAFLD improves insulin resistance and liver function. Histological changes must be corroborated in randomized controlled trials. | Norberto C Chavez-Tapia Tonatiuh Barrientos-Gutierrez Felix I Tellez-ávila Francisco Sánchez-ávila Maria Antonieta Montao-Reyes Misael Uribe | 2006 | World Journal of Gastroenterology2006，12，48： | 11 |
| 2 | Endoscopic and anesthetic feasibility of EUS and ERCP combined in a single session versus two different sessions显示文摘AIM:To discuss the feasibility of single session endoscopic ultrasonography(EUS) to discuss and endoscopic retrograde cholangiopancreatography(ERCP) execution.METHODS:Retrospective endoscopic and anesthetic outcome comparison of performing both EUS and ERCP in a single endoscopic session(Group Ⅰ) versus performing each procedure in two different sessions(Group Ⅱ) was made.The following variables were evaluated:epidemiological variables,American Society of Anesthesiologists Physical Status Classification(ASA) level,procedural time,propofol dose,anesthetic complications,endoscopic complications and diagnostic yield,and therapeutic procedures on both groups.T-student,ChiSquare and Fisher test were used for comparison.RESULTS:We included 39 patients in Group Ⅰ(mean age:69.85 ± 9.25;27 men) and 46 in Group Ⅱ(mean age:67.46 ± 12.57;25 men).Procedural time did not differ significantly between both groups(Group Ⅰvs Group Ⅱ:93 ± 32.78 vs 98.98 ± 38.17;P >0.05) but the dose of propofol differed(Group Ⅰ vs Group Ⅱ:322.28 ± 250.54 mg vs 516.96 ± 289.06 mg;P = 0.001).Three patients had normal findings on both explorations.Three anesthetic complications [O2 desaturation(2),broncoaspiration(1)] and 9 endoscopic complications [pancreatitis(6),bleeding(1),perforation(1),cholangitis(1)] occurred without significant differences between both groups(P > 0.05).We did not find any significant difference regarding age,sex,ASA scale level,diagnostic yield or therapeutic maneuvers between both groups.CONCLUSION:The performance of EUS and ERCP in a single session offers a similar diagnostic and therapeutic yield,does not entail a higher complication risk and requires a significantly smaller dose of propofol for sedation compared with performing each exploration in a different session. | Juan J Vila Marcos Kutz Silvia Goi Miriam Ostiz Edurne Amorena Carlos Prieto Cristina Rodriguez Ignacio Fernández-Urien Francisco J Jiménez | 2011 | World Journal of Gastrointestinal Endoscopy2011，3，3： | 3 |
| 3 | XPD, XPA, ERCC1 and XPG/ERCC5 single nucleotide polymorphisms (SNPs) in oxaliplatin-treated colorectal cancer (CRC) 显示文摘 | Vila JM Moreno I MonzoM | 2004 | ClinOncol2004，22，： | 1 |
| 4 | Informed Dynamic Scheduling for Belief-Propagation Decoding of LDPC Codes 显示文摘 | Vila Casado Andres I Griot Miguel Wesel Richard D | 2007 | IEEE International Conference on Communication2007，，： | 1 |
| 5 | Eocene age of eclogite metamorphism in Pakistan Himalaya: Implications for India-Eurasia collision显示文摘 | Tonarini S Vila I Oberli F | 1993 | Terra Nova1993，5，： | 1 |
| 6 | Hydrogenolysis of glycerol to obtain 1,2-propanediol on Ce-promoted Ni/SBA-15 catalysts显示文摘 | Jiménez-Morales I Vila F Mariscal R | | 0，，： | 1 |
| 7 | On the existence and shape of least energy solutions for some elliptic systems显示文摘 | Andrés I ávila Jianfu Yang | 2003 | Journal of Differential Equations2003，，2： | 1 |
| 8 | Effiux pumps as an important mechanism for quinolone resistance显示文摘 | Vila J Fabrega A Roca I | 2011 | Adv Enzymol Relat Areas Mol Biol2011，，： | 1 |
| 9 | Consumer feelings and behaviors towards well designed websites显示文摘 | Vila N Kuster I | 2011 | Information & Management2011，48，45： | 1 |
| 10 | Novel biopolymer- coated hydroxyapatite foams for removing heavy-metals from polluted water 显示文摘 | VILA M SANCHEZ-SALCEDO S CICUENDEZ M IZQUIERDO-BARBA I VALLET-REGI M | 2001 | Journal of Hazardous Materials2001，192，1： | 1 |
| 11 | Protons and deuterons in magnesium-doped sapphire crystals 显示文摘 | Ramirez R Gonzalez R Colea I and Vila R | 1997 | J Am Ceram Sot1997，80，： | 1 |
| 12 | Comparison between telephone and self-administration of Short Form Health Survey Qusetionnaire(SF-36) 显示文摘 | Garcia M Rohlfs I Vila J | 2005 | Gac Sanit2005，19，6： | 1 |
| 13 | High-performance liquid chromatography with evaporative light-scattering detection for the determination of phospholipid classes in human milk,infant formulas and phospholipid sources of long-chain polyunsaturated fatty acids显示文摘 | SALA VILA A CASTELLOTE-BARGALL(O) A I RODR(I)GUEZ-PALMERO-SEUMA M | 2003 | Journal of Chromatography A2003，1008，1： | 1 |
| 14 | Polymorphisms of the IL12B,IL1B,and TNFA Genes and Susceptibility to Asthma显示文摘 | Padrón-Morales J Sanz C Dávila I | 2013 | J Investig Allergol Clin Immunol2013，23，7： | 1 |
| 15 | Deficit irrigation op- timization of cotton with AquaCrop显示文摘 | Garc I A - Vila M Fereres E Mateos L | 2009 | Agronomy Joumal2009，101，3： | 1 |
| 16 | The impact of Helicobacter pylori on atopic disorders in childhood 显示文摘 | Holster I L Vila A M Caudri D | 2012 | Helicobacter2012，17，3： | 1 |
| 17 | XPD,XPA,ERCC1 and XPG/ERCC5 single nucleotide polymorphisms (SNPs) in oxaliplatin-treated colorectal cancer (CRC)显示文摘 | Vila JM Moreno I Monzo M | 2004 | J Clin Oncology2004，，： | 1 |
| 18 | Interleukin-4(IL4)and Interleukin-4 receptor(IL4RA)polymorphisms in asthma:a case control study显示文摘 | Isidoro-García M Dávila I Laffond E | 2005 | Clin Mol Allergy2005，3，： | 1 |
| 19 | Detection of thyroid dysfunction in pregnant women: universal screening is justified显示文摘 | VILA L VELASCO I GONZ~LEZ S | 2012 | Endocrinol Nutr2012，59，9： | 1 |
| 20 | XPD, XPA, ERCC1 and XPG/ERCC5 single nucleotide polymorphisms (SNPs) in oxalipla- tin-treated colorectal cancer (CRC) 显示文摘 | Vila JM Moreno I Monzo M | 2004 | Journal of Clinical On- cology2004，22，11： | 1 |
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