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| 1 | A prospective randomized antiplatelet trial of cilostazol versus clopidogrel in patients with bare metal stent显示文摘Background Cilostazol is a newly developed antiplatelet drug that has been widely applied for clinical use. Its antiplatelet action appears to be mainly related to inhibition of intracellular phosphodiesterase activity. Recently, cilostazol has been used for antiplatelet therapy after coronary bare metal stent implantation for thrombosis and restenosis prevention. This prospective randomized and double blind trial was designed to investigate the safety and efficacy of cilostazol for the prevention of late restenosis and acute or subacute stent thrombosis. Methods One hundred and twenty patients who underwent elective stent were randomly assigned to treatment group with cilostazol 200 mg/d (n = 60), clopidogrel 75 mg/d and aspirin 100 mg/d or to control group with clopidogrel treatment 75 mg/d (n = 60) and aspirin 100 mg/d. Follow-up coronary angiography was performed 6-9 months later. Results Nine months major adverse cardio-cerebral event (MACCE) were lower in treatment groups (P<0.05). The quantitative coronary angiography (QCA) at 6 months follow-up showed that minimum lumen diameter (MLD) was higher in treatment group than that of control group [(2.14±0.52)mm vs (1.82±0.36)mm, P<0.05]. Late lumen loss (LL) [(0.82±0.42)mm vs (1.31±0.58)mm; P<0.01], restenosis rate (RR) (14% vs 32%; P<0.05) and target lesion revascularizaion (TLR) rate (5% vs 17%; P<0.05) were lower in treatment group than in control group. Conclusion Cilostazol therapy is an effective regimen for prevention not only stent thrombosis but also RR and TLR through reducing MLD without the risk of increasing bleeding. | CHEN Yun-dai, LU Yan-ling, JIN Ze-ning, YUAN Fei and Lü Shu-zhengDepartment of Cardiology, Beijing Anzhen Hospital, Capital University of Medical Sciences Beijing Institute of Heart, Lung and Blood Vessel, Beijing 100029, China | 2006 | Chinese Medical Journal2006,,5: | 15 |
| 2 | Friction Characteristics of Mechanical Seals with Laser-textured Seal Faces显示文摘Heat generated by friction between faces of mechanica l seals is a major factor that causes deterioration of the seals and shortens th eir service life. Excessive temperature rise can greatly alter the seal geometry and vaporize the sealing fluid, resulting in friction of boundary lubrication. These effects on face seals usually lead to excessive leakage and ultimately ren der the seal inoperable. In order to maintain the reliability of seals, high fri ction and unwanted wear must be avoided. Using the laser-texturing process to produce regular micro-surface structures is a fast and convenient technique compared to some more conventional etching or erosion technique currently used by the seal industry for various grooved face seals. Indeed, by using a pulse laser, better control is obtained on the geometr y, size and pore ratio of seal rings made of metallic or ceramic materials. In t his study, seal rings are made of silicon carbide and carbon. Mating faces of th e rings are polished and only silicon carbide rings are laser-textured. The las er texturing can be controlled to produce spherical pores at selected diameters, depths and pore ratio. The textured rings are then super-polished to remove th e bulges formed on the pores rims. After this process the average pore diameter, pore depth and pore ratio reach the predetermined parameter. Some untextured ri ngs are also treated to the same surface roughness and served as a reference for comparison of the textured rings. A special test rig is used to simulate a mech anical seal system and to measure the effect of the laser texturing on friction and seal performance. Tests are performed at various rotational speeds and vario us axial loads. Compared with the conventional mechanical seals, temperature rise, friction torq ue and friction coefficient of mechanical seals with laser-textured seal faces are much lower. These preliminary results show the potential of improving fricti on performance and increasing seal life with laser-textured seal faces. | YU Xin-qi 1,2, HE Song 1, CAI Ren-ling 1 (1. Research Institute of Pressure Vessel and Process Equi pment, East China University of Science and Technology, Shanghai 200237, China 2. College of Mechanical Science and Engineering, Hebei University of Science an d Technology, Shijiazhuang 050018, China) | 2002 | 厦门大学学报(自然科学版)2002,41,S1: | 9 |
| 3 | Recent development in standards of steels used for pressure vessels in China显示文摘In this paper,five items of standards of steels used for pressure vessels which are issued recently or about to be issued and put into effect have been introduced.The differences of standards mentioned above and the former standards and the primary qualifications have been formulated.These qualifications indicate that,some qualifications of national standards of steels used for pressure vessels are on the international advanced level. | ZHANG Xiaohu,GU Xianshang and XU Xiang 1) Hefei General Machinery Research Institute,Hefei 230031,China 2) China National Research Center on Pressure Vessel and Pipeline Safety Engineering,Hefei 230031,China | 2010 | Baosteel Technical Research2010,4,S1: | 3 |
| 4 | PET-CT image registration in the chest using free-form deformations 显示文摘 | Mattes D Haynor D R Vesselle H | 2003 | IEEE Transactions on Medical Imaging2003,22,1: | 1 |
| 5 | Elimination lf artifactal accumulation lf FDG in PET imaging of colorectal cancer显示文摘 | Miraldi F Vesselle H Faulhaber P er al | 1998 | Clin Nucl Med1998,23,: | 1 |
| 6 | Fluorodeoxyglucose uptake of primary non-small cell lung cancer at positron emission tomography:new contrary data on prognostic role显示文摘 | Vesselle H Freeman JD | 2007 | Clin Cancer Res2007,13,11: | 1 |
| 7 | Lung cancer proliferation correlates with fluorodeoxyglucose uptake by positron emission tomography 显示文摘 | Vesselle H Schmidt RA Pugsley JM | 2000 | Clin Cancer Res2000,6,: | 1 |
| 8 | Lung cancer proliferation correlates with fluorodeoxyglucose uptake by positron emission tomography显示文摘 | Schmidt RA Pugsley JM | 2000 | Clin Cancer Res2000,6,10: | 1 |
| 9 | The role of oxidative stress and protein glycation显示文摘 | Simm A Vessel aging | | 0,,03: | 1 |
| 10 | Public and constitutional support for character education显示文摘 | VESSELS G G BOYD S M | 1996 | National Association of Secondary School Principals1996,80,579: | 1 |
| 11 | In vivo validation of 3' deoxy-3'- fluorothymidine (FLT) as a proliferation imaging tracer inhumans:correlation of FLT uptake by positron emission tomography with Ki-67 immunohistochemistry and flow cytometry in human lung tumors显示文摘 | Vesselle H Grierson J Muzi M | 2002 | Clin Cancer Res2002,8,11: | 1 |
| 12 | Influence of heart rate coronary angiography using new multislice computer tomography: experience in 94patients显示文摘 | Schroeder S Kopp AF Kuettner on vessel visibility in noninvasive A | 2002 | Clin Imaging2002,26,2: | 1 |
| 13 | Efficacy of low-dose oral sulodexide in the management of diabetic nephropathy 显示文摘 | Diabetic Albuminuria Vessel Tunisia Study Investigators D Blouza S Dakhli S | 2010 | J Nephrol2010,23,4: | 1 |
| 14 | Lung cancer proliferation correlation with fluorodexuglucose uptake by positron emission tomography显示文摘 | Vesselle H Schmidt RA Pugsley JM | 2000 | Clin Cancer Res2000,6,10: | 1 |
| 15 | Nonrigid muhimo- dality image registration 显示文摘 | MATTES D HAYNOR D R VESSELLE H | 2001 | Medical Imaging2001,4322,1: | 1 |
| 16 | Induction of drup-metabolizing enzymes in liver microsomes of mice and rats by softwood bedding显示文摘 | Vessel E S | | 0,,: | 1 |
| 17 | Lung cancer prolif- eration correlates with ^18F-fluorodeoxyglucose uptake by posi- tron emission tomography显示文摘 | Vesselle H Schmidt R A Pugsley J M | 2000 | Clin Cancer Res2000,6,10: | 1 |
| 18 | PET-CT image registration in the chest using free-form deformations显示文摘 | MATTES D HAYNOR D R VESSELLE H | 2003 | IEEE Trans on Medical Imaging2003,22,1: | 1 |
| 19 | Flu-orodeoxyglucose uptake of primary non-small cell lung cancer at positron emissiontomography: new contrary data on prognostic role 显示文摘 | Vesselle H Freeman JD Wiens L | 2007 | Clin Cancer Res2007,13,: | 1 |
| 20 | 18F-fluorothymicline radiation dosimetry in human PET imaging studies 显示文摘 | Grierson J Peterson LM | 2003 | J Nucl Med2003,44,9: | 1 |