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| 1 | Prevalence and knowledge of hepatitis C in a middle-aged population,Dunedin,New Zealand显示文摘AIM:To determine the prevalence of infection with hepatitis C virus(HCV) in those most at risk of advanced liver disease and to identify gaps in knowledge of HCV.METHODS: Questionnaires were mailed to randomly selected residents aged 40-59 to assess the extent of their general knowledge about HCV. The questionnaire assessed demographics, the extent of general knowledge about viral hepatitis, potential risks for infection and the prevalence of risk factors associated with increased progression of liver fibrosis. Anonymised residual laboratory blood samples from 40-59 years old people from Dunedin taken in hospital or in the community, were tested for HCV antibodies and alanine transaminase(ALT), aspartate transaminase(AST), gamma-glutamyl transpeptidase(GGT). Linear regression was performed to examine whether the demographics sex, age, socio-economic status, qualification level and occupation sector(categorical variables) were predictors of level of general knowledge about hepatitis. For the demographics that werefound to be significant predictors of score outcome, multiple regression analysis was used to determine independent effects. χ2 tests were used to compare our selected sample and our responder population demographics, to the demographics of the entire 40-59 years old population in Dunedin using the 2006 NZ census data. Exact confidence intervals for the proportion positive for HCV and HBV were calculated using the binomial distribution.RESULTS: The response rate to the mailed questionnaire was 431/1400(30.8%). On average 59.4% questions were answered correctly. Predictors for higher scores, indicating greater knowledge about symptoms and transmission included sex(female, P < 0.01), higher level of qualification(P < 0.000) and occupation sector(P < 0.000). Sharing intravenous drug utensils was a known risk factor for disease transmission(94.4%), but the sharing of common household items such as a toothbrush was not. 93% of the population were unaware that HCV infection can be asymptomatic. 25% did not know that treatment was available in New Zealand and of those who did know, only 40% assumed it was funded. Six hundred and eighty-two residual anonymised blood samples were tested for HCV antibodies, ALT, AST and GGT. The prevalence for HCV was 4.01%, 95%CI: 2.6%-5.8%. Liver function tests were not useful for identifying likelyhood of HCV infection.CONCLUSION: Prevalence of HCV in our population is high, and the majority have limited knowledge of HCV and its treatment. | Jane Vermunt Margaret Fraser Peter Herbison Anna Wiles Martin Schlup Michael Schultz | 2015 | World Journal of Gastroenterology2015，21，35： | 3 |
| 2 | latent class modeling as a probabilistic extension of K-means clustering显示文摘 | MAGIDSON J VERMUNT J K | 2002 | Quirk''s Marketing Research Review2002，，： | 1 |
| 3 | Exploring risk groups and risk factors for workplace bullying显示文摘 | Notelaers G Vermunt J K Baillien E | 2010 | Industrial Health2010，9，3： | 1 |
| 4 | Teachers’perceptional identity:An exploratory study from a personal knowledge perspective显示文摘 | Beijaard D Verloop N Vermunt J D | 2000 | Teaching and Teacher Education2000，，16： | 1 |
| 5 | Explicating practical knowledge:an extension of mentor teachers' roles 显示文摘 | Zanting A Verloop N Vermunt J D Van Driel J H | 1998 | European Journal of Teacher Education1998，21，1： | 1 |
| 6 | Effects of dietary a-linolenic acid on the conversion and oxidation of 13C-a-linolenic acid 显示文摘 | Vermunt S H Mensink R P Simonis M M | 2000 | Lipids2000，35，： | 1 |
| 7 | Procedural and distribuitve justice:what is fair depends more on what comes first than on what comes next显示文摘 | Van de Bos K R Vermunt Wilke H A M | | 0，，01： | 1 |
| 8 | Multilevel latent class models 显示文摘 | Vermunt JK | 2003 | Sociological Methodology2003，33，： | 1 |
| 9 | Explicating Practical Knowledge: an extension of mentor teachers’ roles显示文摘 | Anneke Zanting Nico Verloop Jan D. Vermunt Jan H. Van Driel | 1998 | European Journal of Teacher Education1998，，1： | 1 |
| 10 | Measuring the longevity risk in mortality projections 显示文摘 | Brouhns N Denuit M and Vermunt J K | 2002 | Bulletin of tile Swiss Association of Actuaries2002，2，10： | 1 |
| 11 | Consistency and Variability of Learning Strategies in Different University Courses 显示文摘 | Vermetten Y J Lodewijks H G Vermunt J D | 1999 | Higher Education1999，37，1： | 1 |
| 12 | An integrative perspective on social justice:Distributive and procedural fairness evaluations of positive and negative outcome allocations显示文摘 | Tornblom K Y and Vermunt R | 1999 | Social Justice Research1999，12，1： | 1 |
| 13 | Mixed effects logistic regression models for indi-- rectly observed outcome variables 显示文摘 | Vermunt JK | 2005 | Multivariate Behavioral Research2005，40，28： | 1 |
| 14 | Teachers'perceptional identity:An exploratory study from a personal knowledge perspective显示文摘 | BEIJAARD D VERLOOP N VERMUNT J D | 2000 | Teaching and Teacher Education2000，，16： | 1 |
| 15 | Country and consumer segmentation: Multi-level latent class analysis of financial product ownership 显示文摘 | Bijmolt T H A Paas L J Vermunt J K | 2004 | International Journal of Research in Marketing2004，21，4： | 1 |
| 16 | A Poisson log-bilinear regression approach to the construction of projected lifetables显示文摘 | Natacha Brouhns Michel Denuit Jeroen K. Vermunt | 2002 | Insurance Mathematics and Economics2002，，3： | 1 |
| 17 | Teachers' Perceptional Identity: An Exploratory Study from A Personal Knowledge Perspective 显示文摘 | Beijaard D Verloop N Vermunt J D | 2000 | Teaching and Teacher Education2000，16，： | 1 |
| 18 | Procedural and distributive justice :What is fair depends more on what comes first than on what cOmes next 显示文摘 | K VAN DEN BOS R VERMUNT HA M WILKE | 1997 | rnal of Personality and Social Psychology1997，72，1： | 1 |
| 19 | Wilke, Procedural and Distributive Justice: What is Fair Depends More on What Comes First than on What Comes Next 显示文摘 | Van Den Bos K Vermunt R Wilke H A M | 1997 | Journal of Personality and Social Psychology1997，72，1： | 1 |
| 20 | Epitope analysis of the malaria surface antigen pfs48/45 identifies a subdomain that elicits transmission blocking antibodies显示文摘 | Outchkourov N Vermunt A Jansen J | 2007 | J Biol Chem2007，282，17： | 1 |
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