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| 1 | Abnormalities of uterine cervix in women with inflammatory bowel disease显示文摘AIM: To evaluate the prevalence of abnormalities of the uterine cervix in women with inflammatory bowel disease (IBD) when compared to healthy controls. METHODS: One hundred and sixteen patients with IBD [64 with Crohn’s disease (CD) and 52 with ulcerative colitis (UC)] were matched to 116 healthy controls by age (+/- 2 years) at the time of most recent papanicolaou (Pap) smear. Data collected consisted of age, race, marital status, number of pregnancies, abortions/miscarriages, duration and severity of IBD, Pap smear results within five years of enrollment, and treatment with immunosuppressive drugs. Pap smear results were categorized as normal or abnormal including atypical squamous cells of undetermined significance (ASCUS), low-grade squamous intraepithelial lesion (LGSIL), and high-grade squamous intraepithelial lesion (HGSIL). RESULTS: The median age at the time of Pap smear was 46 (range: 17-74) years for the IBD group and matched controls (range: 19-72 years). There were more Caucasian subjects than other ethnicities in the IBD patient group (P = 0.025), as well as fewer abortions (P = 0.008), but there was no significant difference regarding marital status. Eighteen percent of IBD patients had abnormal Pap smears compared to 5% of controls (P = 0.004). Subgroup analysis of the IBD patients revealed no significant differences between CD and UC patients in age, ethnicity, marital status, number of abortions, disease severity, family history of IBD, or disease duration. No significant difference was observedin the number of abnormal Pap smears or the use of immunosuppressive medications between CD and UC patients (P = 0.793). No definitive observation could be made regarding HPV status, as this was not routinely investigated during the timeframe of our study. CONCLUSION: Diagnosis of IBD in women is related to an increased risk of abnormal Pap smear, while type of IBD and exposure to immunosuppressive medications are not. This has significant implications for women with IBD in that Pap smear screening protocols should be conscientiously followed, with appropriate investigation of abnormal results. | Jyoti Bhatia Jason Bratcher Burton Korelitz Katherine Vakher Shlomo Mannor Maria Shevchuk Gworgia Panagopoulos Adam Ofer Ecaterina Tamas Panayota Kotsali Oana Vele | 2006 | World Journal of Gastroenterology2006，12，38： | 3 |
| 2 | The most important bioactive components of cold pressed oil from different pumpkin ( Cucurbita pepo L.) seeds显示文摘 | Biljana B. Rabrenovi? Etelka B. Dimi? Miroslav M. Novakovi? Vele V. Te?evi? Zorica N. Basi? | 2014 | LWT - Food Science and Technology2014，，： | 1 |
| 3 | Histologic multifocality of Tis,T1-2 breast carcinomas implications for clinical trials of breast-conserving surgery 显示文摘 | Holland R Veling SHJ Mravunac M | 1985 | Cancer1985，56，5： | 1 |
| 4 | Histologic multiflcality of Tis, T1-2 breast carcinomas: implications for clinical trials of breast-conserving surgery显示文摘 | Veling SHJ Mravunac M | 1985 | Cancer1985，56，5： | 1 |
| 5 | Symptoms at first contact for psychotic disorder: comparison between native Dutch and ethnic minorities 显示文摘 | Veling W Sehen JP Mackencach JP | 2007 | Schizopbr Res2007，95，13： | 1 |
| 6 | Alexa and oregon green dyes as fluorescence anisotropy probes for measuring protein-protein and protein nucleic acid interactions显示文摘 | RUSINOVA E TRETYACHENKO LADOKHINA V VELE O E | 2002 | Analytical Biochemistry2002，308，1： | 1 |
| 7 | Incidence of schizophrenia among ethnic minorities in the Netherlands: a four-year first- contact study显示文摘 | Veling W Sehen JP Veen N | 2006 | Schizophr Res2006，86，13： | 1 |
| 8 | Leukotriene modifier therapy for mild sleep-Disordered Breathing in children 显示文摘 | Goldbart AD Goldman JL Veling MC | 2005 | Am J Respir Crit Med2005，172，： | 1 |
| 9 | Leukotriene modifier therapy for mild sleep-disordered breathing in children显示文摘 | Goldbart AD Goldman JL Veling MC | 2005 | Am J Respir Crit Care Med2005，172，3： | 1 |
| 10 | The validity of thel6-Item Version of the Prodromal Questionnaire (PQ-16) to screen for ultra high risk of developing psychosis in the general help-seeking population 显示文摘 | Ising HK Veling W Loewy RL | 2012 | Schizophr Bull2012，38，6： | 1 |
| 11 | Symptoms at first contact for psychotic disorder: comparison between native Dutch and ethnic minorities 显示文摘 | Veling W Selten JP Mackencach JP | 2007 | Schizophr Res2007，95，： | 1 |
| 12 | Incidence of schizophrenia among ethnic minorities in the Netherlands : a four-year first-contact study 显示文摘 | Veling W Selten JP Veen N | 2006 | Schizophr Res2006，86，： | 1 |
| 13 | Tracer experiments in the Rhine Basin:evaluation of the skewness of observed concentration distributions显示文摘 | MAZIJK A V VELING E J M | 2005 | Journal of Hydrology2005，307，1234： | 1 |
| 14 | Leukotriene modifier therapy for mild sleep-disordered breathing in children显示文摘 | Goldbart AD Goldman JL Veling MC | | 0，，03： | 1 |
| 15 | Leukotriene modifier therapy for mild sleep - disordered breathing in children 显示文摘 | Goldbart AD Goldman JL Veling MC | 2005 | Am J Respir Crit Care Med2005，172，3： | 1 |
| 16 | Histologic multifocality of Tis T1-2 breast carcinomas:implications for clinical trials of breast-conserving therapy显示文摘 | Holland R Veling S Mravunac M | 1985 | Cancer1985，56，5： | 1 |
| 17 | Glucocorticoid receptor subunit expression in adenotonsillar tissue of children with obstructive sleep apnea显示文摘 | Goldbart A D Veling M C Goldman J L | 2005 | Pediatr Res2005，57，： | 1 |
| 18 | Leukotriene modifier therapy for mild sleep-disordered breathing in children显示文摘 | Goldbart AD Goldman JL Veling MC | 2005 | Am J Respir Crit Care Med2005，172，3： | 1 |
| 19 | Histologic multiflicality of Tis T1- 2 breast carcinomas:implications for clinical trials of breast-coserving surgery显示文摘 | Veling SHJ Mravunal M | 1985 | Cancer1985，56，5： | 1 |
| 20 | Efficacy and safety of oral ridogrel in the treatment of ulcerative colitis two muticentre, randomized, double-blind studies 显示文摘 | TYTGAT GN VAN NUETEN L VAN DE VELED | 2002 | Aliment Phamacol Ther2002，16，1： | 1 |
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