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| 1 | Press-pack IGBTs for HVDC and FACTS显示文摘The popularity of insulated gate bipolar transistors(IGBTs)for use in high-voltage direct current(HVDC)transmission and flexible AC transmission systems(FACTS)is increasing.Unfortunately,for these applications wire-bond IGBT technology has a number of shortcomings,such as insufficient current ratings for the most powerful schemes,and inability to fail to short-circuit.Press-pack IGBT technology,conversely,offers increased current ratings,and an inherent short-circuit failure mode,making it a more attractive choice for HVDC and FACTS.However,the design and manufacture of these devices requires a comprehensive understanding of the unique technical challenges,which differ markedly from those for wirebond modules or traditional pressure contact devices.Specific challenges include providing a high degree of mechanical protection for the IGBT chip against normal operating stresses.Furthermore,it is essential to achieve uniform contact pressure across each chip surface to ensure optimum performance.To achieve this,manufacturers have designed products that use rigid copper electrodes manufactured to tighter tolerances than for other pressure contact devices,such as thyristors,and products that use compliant electrodes,incorporating spring assemblies.Dynex is in the advanced stages of development of press-pack IGBT technology with demonstrated robust solutions for the technical challenges outlined in this paper.Design success has been achieved through the use of state-of-the-art simulations in conjunction with a long history of manufacturing expertise for bipolar and IGBT products.Finally,multiple press-pack IGBT variants are currently undergoing evaluation tests prior to product release. | Robin Simpson Ashley Plumpton Michael Varley Charles Tonner Paul Taylor Xiaoping Dai | 2017 | CSEE Journal of Power and Energy Systems2017，3，3： | 10 |
| 2 | 仔猪饮水和体重的关系显示文摘对仔猪来说 ,吃和喝是紧密相连的。若没有足够的饮水 ,是很难使仔猪吃下大量干饲料的。遗憾的是 ,许多养猪者都没有认识到清洁而方便的饮水源对于仔猪有多么重要。 | 陈云清 Mike Varley Philip Stockhill | 2002 | 国外畜牧学(猪与禽)2002，，1： | 5 |
| 3 | MicroRNAs and liver cancer associated with iron overload:Therapeutic targets unravelled显示文摘Primary liver cancer is a global disease that is on the increase.Hepatocellular carcinoma(HCC)accounts for most primary liver cancers and has a notably low survival rate,largely attributable to late diagnosis,resistance to treatment,tumour recurrence and metastasis.MicroRNAs(miRNAs/miRs)are regulatory RNAs that modulate protein synthesis.miRNAs are involved in several biological and pathological processes including the development and progression of HCC.Given the poor outcomes with current HCC treatments,miRNAs represent an important new target for therapeutic intervention.Several studies have demonstrated their role in HCC development and progression.While many risk factors underlie the development of HCC,one process commonly altered is iron homeostasis.Iron overload occurs in several liver diseases associated with the development of HCC including Hepatitis C infection and the importance of miRNAs in iron homeostasis and hepatic iron overload is well characterised.Aberrant miRNA expression in hepatic fibrosis and injury response have been reported,as have dysregulated miRNA expression patterns affecting cell cycle progression,evasion of apoptosis,invasion and metastasis.In2009,miR-26a delivery was shown to prevent HCC progression,highlighting its therapeutic potential.Several studies have since investigated the clinical potential of other miRNAs with one drug,Miravirsen,currently in phaseⅡclinical trials.miRNAs also have potential as biomarkers for the diagnosis of HCC and to evaluate treatment efficacy.Ongoing studies and clinical trials suggest miRNA-based treatments and diagnostic methods will have novel clinical applications for HCC in the coming years,yielding improved HCC survival rates and patient outcomes. | Catherine M Greene Robert B Varley Matthew W Lawless | 2013 | World Journal of Gastroenterology2013，19，32： | 5 |
| 4 | 蛋白酶和木聚糖酶对育肥猪的生长性能、营养消化率以及粪便气味的影响显示文摘菜籽粕(RSM)和小麦干酒糟及其可溶物(DDGS)作为副产物可应用到猪的日粮中。然而,与小麦和豆粕型日粮相比,RSM和DDGS中含有较高的非淀粉多糖(NSP),其可限制猪对日粮的有效利用。采用2×2因素试验设计研究生长育肥猪饲粮中添加木聚糖酶(0和200mg·kg-1)和蛋白酶(0和200mg·kg-1)对其生长性能、胴体品质、表观回肠消化率、全消化道养分消化率及粪便气体排放的影响及两种酶之间的相互作用。试验1,对猪的生长性能进行评估。将体重为34.2±2.1kg的育肥猪128头随机分配到4个处理组:以DDGS(300g·kg-1)和RSM(210g·kg-1)的基础日粮;基础日粮中添加蛋白酶200mg·kg-1;基础日粮中添加木聚糖酶200mg·kg-1;基础日粮中添加蛋白酶200mg·kg-1和木聚糖酶200mg·k-1。试验1中,在生长育肥-出栏期间(0~出栏),日粮中添加蛋白酶的试验猪较不添加蛋白酶的试验猪相比具有较低的平均日增重(ADG)(P〈0.001)。生长阶段(0—28d),蛋白酶和木聚糖酶对猪的日均采食量(ADFI,P〈0.01)和体重(BW,P〈0.01)的影响存在相互作用。在育肥阶段(28d~出栏),日粮中添加蛋白酶和木聚糖酶的试验猪与仅添加一种没酶的试验猪相比具有较低的ADFI和BW。然而,蛋白酶和木聚糖酶的相互作用在生长期间(0~28d)内并不显著。试验2,选择体重78±2.3kg公猪24只,将其置于代谢笼中进行代谢试验,试验期间按照试验l中的日粮进行饲喂。木聚糖酶和蛋白酶对总能(GE)中的AID存在相互作用(P〈0.05)。与对照组相比,饲粮中添加蛋白酶可以增加GE中的AID,但饲粮中添加两种酶时可降低GE中的AID。饲粮中添加木聚糖酶交不添加木聚糖组相比,猪粪便的臭气排放量降低(598和1306OuE/m3;P〈0.05)。研究表明,蛋白酶可提高GE的AID;木聚糖酶可以减少粪便异味的排放,然而当生长猪育肥以RSM和DDGS为基础饲粮时,两种酶均不能提高其生长性能。 | O'Shea C J Mc Alpine P O Solan P Curran T Varley P F Walsh A M Doherty J V O | 2014 | 饲料博览2014，0，10： | 4 |
| 5 | 功能性饲料在猪上的应用显示文摘营养技术上的最新研究进展表明,许多饲料原料除了它们所拥有的营养作用外还具有很多其它功能。这些功能性饲料在人类营养上被称之为'多功能食物',它们能够改善整个日粮的营养价值以及食用者的健康和福利。在猪的营养方面,功能性饲料在提高猪的多方面性能上发挥着主要作用。 | 张晓玲 Mike Varley | 2009 | 国外畜牧学(猪与禽)2009，，4： | 2 |
| 6 | Laser in situ keratomileusis for myopia and astigmatism: safety and efficacy显示文摘 | Alan Sugar Christopher J Rapuano William W Culbertson David Huang Gary A Varley Peter J Agapitos Vincent P de Luise Douglas D Koch | 2002 | Ophthalmology2002，，1： | 2 |
| 7 | 饲料转化率的控制显示文摘饲料转化率(Feed Conversion Ratio,FCR)是商品肉猪场生产性能的一个反映,采食量和增重则是FCR的完整组成部分,但是影响它们的因素很复杂。因此,一群猪的FCR值可能会大幅变动。在大多数现代养猪场,更详细地监测会影响FCR的因素并寻找改善它的方法可能是有道理的。 | 刘艳枝 Mike Varley | 2010 | 国外畜牧学(猪与禽)2010，，3： | 2 |
| 8 | New inductive population model for insect parasites and its bearing on biological control显示文摘 | HASELL M P VARLEY G C | 1969 | Nature1969，223，： | 1 |
| 9 | Studies on blends of epoxy-funetionalized hyperbranched polymer and epoxy resin 显示文摘 | PATNA D VARLEY RUSSELL J SINGH RAMAN RK | 2003 | Journal of Material Science2003，38，1： | 1 |
| 10 | Urothelial differentiation in chronically urine-deprived bladders of patients with end-stage renal disease 显示文摘 | Stahlschmidt J Varley CL Toogood G | 2005 | Kidney Int2005，68，3： | 1 |
| 11 | The uses of passive measurement of acoustic emissions from chemical engineering processes 显示文摘 | Boyd J W R Varley J | 2001 | Chemical Engineering Science2001，56，5： | 1 |
| 12 | New inductive population model for insect parasites and its bearing on biologicalcontrol 显示文摘 | Hassell M P Varley G C | 1969 | Nature1969，223，： | 1 |
| 13 | New inductive population model for insect parasites and its bearing on biological control显示文摘 | HASSELL M P VARLEY GC | 1969 | Nature1969，223，： | 1 |
| 14 | Toughening of trifunctional epoxy using an epoxy-functionalized hyperhranched polymer显示文摘 | RATNA D VARLEY RUSSELL J SIMON GP | 2003 | Journal of Applied Polymer Science2003，89，9： | 1 |
| 15 | Neural Systems Involved in ‘theory of mind' 显示文摘 | Siegal M Varley R | 2002 | Nature Neuroscience2002，3，： | 1 |
| 16 | New inductive population model for insect parasites and its bearing on biological control 显示文摘 | HASSELL M P VARLEY G C | 1969 | Nature1969，223，1： | 1 |
| 17 | Hardware Implementations of Multi-layer Feed forward Neural Networks and Error Back propagation Using 8-bit PIC Microcontrollers显示文摘 | Tang J Varley M R Peak M S | | 0，，： | 1 |
| 18 | Perspectives of adolescents with attention-deficit hyperactivity disorder do matter显示文摘 | Varley CK | | 0，，01： | 1 |
| 19 | The production of Surfactin in batch culture by Bacillus subtilis ATCC21332 is strongly influenced by the conditions of nitrogen metabolism显示文摘 | DAVIS D A LYNCH H C VARLEY J | 1999 | Enzyme and Microbial Technology1999，25，： | 1 |
| 20 | BRCA1,BRCA2 and TP53 mutations in very early-onset breast cancer with associated risks to relatives显示文摘 | Lalloo F Varley J Moran A | 2006 | Eur J Cancer2006，42，8： | 1 |
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