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| 1 | Nat Genet:单基因突变导致过敏性皮炎的发生显示文摘最近,研究者们鉴定出了一类导致神经性皮炎发生的关键基因突变:CARDll。来自美国NIH过敏与传染病研究所的研究者们通过对四个没有血缘关系的患病家庭进行分析,发现了这一导致疾病产生的基因、 | Chi A Ma, Yuan Zhang, Michael A Weinreich, Jonathan J Lyons, Celeste G Nelson, Thomas DiMaggio, Kelly D Stone, Joshua D Milner Jeffrey R Stinson, Elisa Ruffo, Batsukh Dorjbal, Swadhinya Arjunaraja, Kelsey Voss, Andrew L Snow Jordan K Abbott, Pia J Hauk, Paul R Reynolds, Erwin W Gelfand Elisa Ruffo Salomé Glauzy, Natsuko Yamakawa, Eric Meffre Jennifer Stoddard, Julie Niemela, Sergio D Rosenzweig Yu Zhang, Helen F Matthews Joshua J McElwee Nina Jones Alejandro Palma, Matías Oleastro, Emma Prieto, Andrea R Bernasconi, Geronimo Dubra, Silvia Danielian, Jonathan Zaiat, Marcelo A Marti Brian Kim Megan A Cooper Neil Romberg | 2017 | 现代生物医学进展2017，17，27： | 3 |
| 2 | Establishing minimum clinically important difference values for the Patient-Reported Outcomes Measurement Information System Physical Function, hip disability and osteoarthritis outcome score for joint reconstruction, and knee injury and osteoarthritis out显示文摘AIM To establish minimum clinically important difference(MCID) for measurements in an orthopaedic patient population with joint disorders.METHODS Adult patients aged 18 years and older seeking care for joint conditions at an orthopaedic clinic took the Patient-Reported Outcomes Measurement Information System Physical Function(PROMIS~? PF) computerized adaptive test(CAT), hip disability and osteoarthritis outcome score for joint reconstruction(HOOS JR), and the knee injury and osteoarthritis outcome score for joint reconstruction(KOOS JR) from February 2014 to April 2017. MCIDs were calculated using anchorbased and distribution-based methods. Patient reports of meaningful change in function since their first clinic encounter were used as an anchor.RESULTS There were 2226 patients who participated with a mean age of 61.16(SD = 12.84) years, 41.6% male, and 89.7% Caucasian. Mean change ranged from 7.29 to 8.41 for the PROMIS~? PF CAT, from 14.81 to 19.68 for the HOOS JR, and from 14.51 to 18.85 for the KOOS JR. ROC cut-offs ranged from 1.97-8.18 for the PF CAT, 6.33-43.36 for the HOOS JR, and 2.21-8.16 for the KOOS JR. Distribution-based methods estimated MCID values ranging from 2.45 to 21.55 for the PROMIS~? PF CAT; from 3.90 to 43.61 for the HOOS JR, and from 3.98 to 40.67 for the KOOS JR. The median MCID value in the range was similar to the mean change score for each measure and was 7.9 for the PF CAT, 18.0 for the HOOS JR, and 15.1 for the KOOS JR.CONCLUSION This is the first comprehensive study providing a wide range of MCIDs for the PROMIS? PF, HOOS JR, and KOOS JR in orthopaedic patients with joint ailments. | Man Hung Jerry Bounsanga Maren W Voss Charles L Saltzman | 2018 | World Journal of Orthopedics2018，9，3： | 3 |
| 3 | Recent advances in the biogeochemistry of nitrogen in the ocean显示文摘 | NAQVI S W A VOSS M MONTOYA J P | 2008 | Biogeosciences Discus- sions2008，5，： | 1 |
| 4 | Role of proliferation in the toxicity of fumonisin B1 :enhanced hepatotoxic response in the partially hepatectomized rat 显示文摘 | Li W Riley RT Voss KA | 2000 | J Toxicol Environ Health A2000，60，7： | 1 |
| 5 | Systemic and local immunosuppression in pancreatic cancer patients 显示文摘 | Von Bernstorff W Voss M Freichel S | 2001 | CIin Cancer Res2001，7，3： | 1 |
| 6 | Gender differences in the outcome of cardiac interventions 显示文摘 | Tillmanns H Waas W Voss R | 2005 | Herz2005，30，5： | 1 |
| 7 | Single chain antibody(SCA) encoding genes:one-step construction and expression in eukaryotic cells显示文摘 | Davis G T Bedzyk W D Voss E W | 1991 | Biotechnology1991，9，2： | 1 |
| 8 | Exercise training increases size of hippocampus and improves memory 显示文摘 | ERICKSON K I VOSS M W PRAKASH R S et al | 2011 | Proc Natl Aead Sci U S A2011，108，7： | 1 |
| 9 | Intergeneric transfer of nematode resistance from Raphanus sativus into the Brassica napus genome显示文摘 | Voss A Snowdon R J L(u)hs W | 2000 | Acta Hortic2000，539，： | 1 |
| 10 | Ex- ercise training increases size of hippocampus and im- proves memory显示文摘 | Erickson K I Voss M W Prakash R S | 2011 | Proc Natl Acad Sci U S A2011，108，7： | 1 |
| 11 | E-eadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells显示文摘 | Frixen UH Behnens J Sachs M Eberle G Voss B Warda A Lochner D Birchmeier W | | 0，，： | 1 |
| 12 | Single chain antibody encoding genes:one step construction and expression in eukaryotic cells显示文摘 | Davis G T Bedzyk W D Voss E W | 1991 | Biotechnology1991，88，9： | 1 |
| 13 | Passive immunotherapy in simian immunodeficiency virus-infected macaques accelerates the development of neutralizing antibodies显示文摘 | Haigwood N L Montefiori D C Sutton W F McClure J Watson A J Voss G Hirsch V M Richardson | | 0，，11： | 1 |
| 14 | STAT3 and COX-2 activation in the guinea-pig brain during fever induced by the Toll-like receptor-3 agonist polyinosinic:polycytidylic acid显示文摘 | Voss T Barth S W Rummel C | 2007 | Cell and tissue research2007，328，3： | 1 |
| 15 | Comparing the feeding habits of co-occurring sprat (Sprattus sprattus) andcod (Gadus morhua ) larvae in the Bornholm Basin, Baltic Sea显示文摘 | VOSS R KOSTER F W DICKMANN M | 2003 | Fisheries Research2003，63，1： | 1 |
| 16 | Systemic and local immunosuppression in pancreatic cancer patients 显示文摘 | yon Bernstorff W Voss M Freichel S | 2001 | Clin cancer Res2001，7，3： | 1 |
| 17 | Aerobic fitness is associated with hippoeampal volume in elderly humans 显示文摘 | ERICKSON K I PRAKASH R S VOSS M W | 2009 | Hippocampus2009，19，10： | 1 |
| 18 | Gender differences in the outcome of cardiac interventions显示文摘 | Tillmanns H Waas W Voss R | 2005 | Herz2005，30，5： | 1 |
| 19 | A preliminary investigation on renal and hepatic toxicity in rats fed purified fumonisin Bt 显示文摘 | Voss K A Chamberlain W J Bacon C W | 1993 | Natural Toxins1993，1，4： | 1 |
| 20 | Deracemization of secondary alcohols through a concurrent tandem biocatalytic oxidation and reduction显示文摘 | VOSS C V GRUBER C C KROUTIL W | 2008 | Angewandte Chemie-International Edition2008，47，4： | 1 |
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