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| 1 | Experimental obstructive jaundice alters claudin-4 expression in intestinal mucosa: Effect of bombesin and neurotensin显示文摘瞄准:调查试验性的妨碍的黄疸和外长的 bombesin 和 neurotensin (NT )(BBS ) 的影响紧密的连接(TJ ) 的表示上的管理在老鼠的肠上皮的蛋白质 claudin-4。方法:四十只男 Wistar 老鼠随机被划分成五个组:我 = 控制, II = 假冒操作, III = 胆汁管结扎(BDL ) , IV = BDL+BBS (30 microg/kg 每 d ) , V = BDL+NT (300 microg/kg 每 d ) 。在 d 的实验的结束 10,内毒素在门和大动脉的血被测量。终端回肠的织物节组织学地被检验并且免疫组织化学地为在肠上皮的 claudin-4 表示的评估。结果:妨碍的黄疸导致了重要的门和大动脉的 endotoxemia 表明的肠的障碍失败。Claudin-4 表示显著地被增加在上面在 jaundiced 老鼠的第三根绒毛并且一起来它的侧面的分发的规定被注意。BBS 或 NT 的管理恢复了 claudin-4 表示到控制状态并且显著地减少了门和大动脉的 endotoxemia。结论:在肠上皮的试验性的妨碍的黄疸增加 claudin-4 表示,它可以是贡献粘膜障碍的混乱的一个关键因素。毁坏规章的肽 BBS, NT 能阻止这扇改变和还原剂门和全身的 endotoxemia。 | Stelios F Assimakopoulos Constantine E Vagianos Aristides S Charonis Ilias H Alexandris Iris Spiliopoulou Konstantinos C Thomopoulos Vassiliki N Nikolopoulou Chrisoula D Scopa | 2006 | World Journal of Gastroenterology2006，12，21： | 21 |
| 2 | Endoparasitoid wasp bracovirus-mediated inhibition of hemolin function and lepi- dopteran host immunosuppression显示文摘 | VASSILIKI L VASSILIS D DIMITRA S | 2008 | Cellular Microbiology2008，10，10： | 1 |
| 3 | Eta-1 (osteopontin):a nearly component of type-1 ( cell mediated) immunity显示文摘 | Ashkar S Georg FW Vassiliki P | 2000 | Science2000，287，： | 1 |
| 4 | A Simple method for the alkalinc hydrolysis of ester 显示文摘 | VASSILIKI T KONSTANTINOS S ANDRESS G T | 2007 | Tetrahedr Lett2007，48，46： | 1 |
| 5 | A simple method for the alkaline hydrolysis of esters 显示文摘 | Vassiliki T Konstantinos S Andreas G T | 2007 | Tetrahedron Letters2007，48，46： | 1 |
| 6 | Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications 显示文摘 | Nicholas Mitsiades Constantine S Mitsiades Vassiliki Poulaki | 2002 | Blood2002，99，： | 1 |
| 7 | Bluetongue virus diagnosis of clinical cases by a duplex reverse transcription-PCR: a comparison with conventional methods 显示文摘 | Charalambos B Maria K Vassiliki S | 2001 | J Virol Methods2001，98，： | 1 |
| 8 | Eta-1 (osteopontin):An early component of type-1 ( cellmediated ) immunity 显示文摘 | Ashkar S Georg FW Vassiliki P | 2000 | Science2000，287，： | 1 |
| 9 | Structure and Thermodynamics of Carbon and Carbon/Silicon Precursors to Nanostructures显示文摘 | Vassiliki A G Jerry A B Mark S G | 2002 | Journal of American Chemical Society2002，124，21： | 1 |
| 10 | Eta21 (osteopontin) : An early component of type-1 (cellmediated) immunity 显示文摘 | Ashkar S Georg F W Vassiliki P | 2000 | Science2000，287，： | 1 |
| 11 | Serum transferrin receptor,ferritin,and reticulocyte maturity indices during the fwst year of life in‘large'preterm infants显示文摘 | VASSILIKI S VASILEIOS G KONSTANTINA P | 2007 | Ear J Haem2007，79，： | 1 |
| 12 | Cytoreductive 外科和 hyperthermic intraperitoneal chemoperfusion : 亚利桑那早经验的大学显示文摘 AIM:To evaluate the safety and effectiveness of our new cytoreductive surgery(CRS)and hyperthermic intraperitoneal chemoperfusion(HIPEC)program.METHODS:Retrospective review of patients with gastrointestinal malignancies who were suitable candidates for CRS and HIPEC between 12/1/2009 and 10/1/2010.All clinicopathologic data were reviewed with a special focus on the surgical outcome and the postoperative morbidity and mortality.RESULTS:Fourteen patients were identified.Median age was 64 years;seven were female.The primary tumors were:colonic(29%),appendiceal(36%),peritoneal mesothelioma(14%),gastric(7%),adenocarcinoma of unknown primary(7%),and gastrointestinal stromal tumor(7%).Eleven patients(79%)received CRS/HIPEC,three for palliation.Three patients that did not undergo CRS/HIPEC had an average peritoneal cancer index(PCI)of 25.The eight patients that underwent curative CRS/HIPEC had an average PCI of 10 and a completeness of cytoreduction score of 0(87.5%) or 1(12.5%).Postoperative morbidity was 36%;the worst adverse event was Grade 3 ileus.Mortality rate was 0%.CONCLUSION:CRS with HIPEC is safe and feasible at tertiary institutions with fledgling programs.PCI is an accurate predictor of surgical outcomes. | Ioannis T Konstantinidis Christine Young Vassiliki L Tsikitis Ellyn Lee Evan S Ong | 2012 | World Journal of Gastrointestinal Surgery2012，4，6： | 0 |
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