|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Contribution of the IL-17/IL-23 axis to the pathogenesis of inflammatory bowel disease显示文摘Inflammatory bowel diseases(IBDs) are chronic disorders of modern society, requiring management strategies aimed at prolonging an active life and establishing the exact etiology and pathogenesis.These idiopathic diseases have environmental, genetic,immunologic, inflammatory, and oxidative stress components. On the one hand, recent advances have shown that abnormal immune reactions against the microorganisms of the intestinal flora are responsible for the inflammation in genetically susceptible individuals. On the other hand, in addition to T helper cell-type(Th) 1 and Th2 immune responses,other subsets of T cells, namely regulatory T cells and Th17 maintained by IL-23 are likely to develop IBD. IL-23 acts on innate immune system members and also facilitates the expansion and maintenance of Th17 cells. The IL-17/IL-23 axis is relevant in IBD pathogenesis both in human and experimental studies. Novel biomarkers of IBD could be calprotectin,microRNAs, and serum proinflammatory cytokines.An efficient strategy for IBD therapy is represented by the combination of IL-17 A and IL-17 F in acute IL-17 A knockout TNBS-induced colitis, and also definite decrease of the inflammatory process in IL-17 F knockout, DSS-induced colitis have been observed.Studying the correlation between innate and adaptive immune systems, we hope to obtain a focused reviewin order to facilitate future approaches aimed at elucidating the immunological mechanisms that control gut inflammation. | Cristina-Sorina Cǎanǎ Ioana Berindan Neagoe Vasile Cozma Cristian Magdas Flaviu Tǎbǎan Dan Lucian Dumitrasu | 2015 | World Journal of Gastroenterology2015，21，19： | 37 |
| 2 | Architecture of a protein central to iron homeostasis: crystal structure and spectroscopic analysis of the ferric uptake regulator显示文摘 | Pohl E Haller J C Mijovilovich A Meyer-Klaucke W Garman E Vasil M L | 2003 | Molecular Microbiology2003，47，4： | 1 |
| 3 | Chemically assisted sputter etching of permalloy using CO or CI2 显示文摘 | VASILE M J MOGAB C J | 1986 | Journal of Vacuum Science & Technology: A1986，4，3： | 1 |
| 4 | Thermoxidative decomposition of some polysulfones under dynamic conditions of heating显示文摘 | VASILE C COSTEA E PASCU M C | 1998 | J of Therm Anal1998，52，2： | 1 |
| 5 | Inherited germline T790M mutation and somatic epidermal growth factor re- ceptor mutations in non-small cell lung cancer patients显示文摘 | Tibaldi C Giovannetti E Vasile E | 2011 | J Thorac Oncol2011，6，2： | 1 |
| 6 | A marker genes collection and RAPD markers for recessive branching in sun- flower 显示文摘 | IUORAS M PATRASCU M VASILE C | 1999 | Helia1999，22，30： | 1 |
| 7 | Ni-exchanged AlMCM-41:An efficient bifunctional catalyst for ethylene oligomerization显示文摘 | Fran(c)ois F | 2004 | Journal of Catalysis2004，225，： | 1 |
| 8 | Correlation of CDA, ERCC1, and XPD polymorphisms with response and survival in gemcitabine/eisplatiwtreated advanced non small cell lung cancer patients显示文摘 | Tibaldi C Giovannetti E Vasile E | 2008 | Clin Cancer Res2008，14，6： | 1 |
| 9 | Innovative design of a magnetocaloric system 显示文摘 | C Vasile C Muller | 2006 | International Journal of Refrigeration2006，29，8： | 1 |
| 10 | First line chemothera-py with planned sequential administration of gemcitabine fol-lowed by docetaxel in elderly advanced non-small-cell lung canc-er patients:a multicenter phase II study显示文摘 | Tibaldi C Vasile E Antonuzzo A | 2008 | Br J Cancer2008，98，： | 1 |
| 11 | The Influence of the Lubricant Viscosity on the Rolling Friction Torque 显示文摘 | Dumitru N O Mihaela R D B Vasile C S | 2014 | Tribology International2014，72，： | 1 |
| 12 | Hydrogen-bonding interaction of an alternating maleic acid-vinyl acetate eopolymer with po显示文摘 | Vasile C Bumbu G G Mylonas Y | 2003 | Polym Int2003，52，12： | 1 |
| 13 | Characterization of the ehitosan/layered silicate nanoeomposites 显示文摘 | Cheaburu C N Vasile C Duraecio D | 2009 | Solid State Phenome- na2009，151，1： | 1 |
| 14 | Correlation of CDA, ERCC1, and XPD Polymorphisms with Response and Survival in Gemeitabine/Cisplatin-Treated Advanced Non-Small Cell Lung Cancer patients显示文摘 | Tibaldi C Giovannetti E Vasile E | 2008 | Clin Cancer Res2008，14，8： | 1 |
| 15 | The characterization of recycled PMMA显示文摘 | Popescu V Vasile C Brebu M | 2009 | Journal of Alloys and Compounds2009，483，12： | 1 |
| 16 | Influence of the acidbase properities of solid catalysts derived from hydrotalicite like compounds on the condensation of formaldehyde and acetaldehyde显示文摘 | Dumitriu E Vasile H Carmen C | 1987 | Journal of Catalysis1987，107，1： | 1 |
| 17 | Thermal degradation of lignin-a review 显示文摘 | BREBU M VASILE C | 2010 | Cellulose Chemistry and Technology2010，44，9： | 1 |
| 18 | Semi-analytical solution for the optimal Low-Thrust deflection of Near-Earth objects 显示文摘 | Colombo C Vasile M Radice G | 2009 | Journal of Guidance Control and Dynamics2009，32，3： | 1 |
| 19 | Localiza tion and interaction of thecis element for ABA, VP1 and light activation of the C1 gene of maize显示文摘 | Kao C Y Cocciolone S M Vasil I K | 1996 | Plant Ce111996，8，7： | 1 |
| 20 | Portal Cavernoma: Dynamic CT Features and Transient Differences in Hepatic Attenuation显示文摘 | Mathieu D Vasile N Dibie C | 1985 | Radiology1985，，154： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员