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| 1 | Role of perinatal long-chain omega-3 fatty acids in cortical circuit maturation:Mechanisms and implications for psychopathology显示文摘Accumulating translational evidence suggests that the long-chain omega-3 fatty acid docosahexaenoic acid(DHA) plays a role in the maturation and stability of cortical circuits that are impaired in different recurrent psychiatric disorders. Specifically, rodent and cell culture studies find that DHA preferentially accumulates in synaptic and growth cone membranes and promotes neurite outgrowth, dendritic spine stability, and synaptogenesis. Additional evidence suggests that DHA may play a role in microglia-mediated synaptic pruning, as well as myelin development and resilience. In nonhuman primates n-3 fatty acid insufficiency during perinatal development leads to widespread deficits in functional connectivity in adult frontal cortical networks compared to primates raised on DHA-fortified diet. Preterm delivery in non-human primates and humans is associated with early deficits in cortical DHA accrual. Human preterm birth is associated with longstanding deficits in myelin integrity and cortical circuit connectivity and increased risk for attention deficit/hyperactivity disorder(ADHD), mood, and psychotic disorders. In general, ADHD and mood and psychotic disorders initially emerge during rapid periods of cortical circuit maturation and are characterized by DHA deficits, myelin pathology, and impaired cortical circuit connectivity. Together these associations suggest that early and uncorrected deficits in fetal brain DHA accrual may represent a modifiable risk factor for cortical circuit maturation deficits in psychiatric disorders, and could therefore have significant implications for informing early intervention and prevention strategies. | Robert K McNamara Jennifer J Vannest Christina J Valentine | 2015 | World Journal of Psychiatry2015，5，1： | 2 |
| 2 | Auxin-mediated cell cycle activation during early lateral root initiation显示文摘 | Himanen K Boucheron E Vanneste S | 2002 | The plant cell2002，14，： | 1 |
| 3 | Functional MRI of language lateralization during development in children显示文摘 | HOLLAND S K VANNEST J MECOLI M | 2007 | Int J Audiol2007，46，： | 1 |
| 4 | Ethylene regulates root growth through effects on auxin biosynthesis and transport-dependent auxin distribution显示文摘 | Ruzicka K Ljung K Vanneste S | 2007 | Plant Cell2007，19，7： | 1 |
| 5 | The genome sequence of the orchid Phalaenopsis equestris显示文摘 | Cai J Liu X Vanneste K | 2015 | Nature Generics2015，，1： | 1 |
| 6 | Auxinmediated Cell Cycle activation duringearly lateral root initiation显示文摘 | Himanen K Boucheron E Vanneste S | 2002 | Plant Cell2002，14，： | 1 |
| 7 | Transcript profiling of early lateral root initiation显示文摘 | Himanen K Vuylsteke M Vanneste S | 2004 | Proc Natl Acad Sci USA2004，101，： | 1 |
| 8 | Explaining differences in productive efficiency: an appli- cation to Belgian Municipalities显示文摘 | De BORGER B KERSTENS K MOESEN W VANNESTE J | 1994 | Public Choice1994，80，34： | 1 |
| 9 | Late Quaternary earthquake-related soft-sediment deformation along the Belgian portion of the Feldbiss Fault,Lower Rhine Graben system显示文摘 | VANNESTE K MEGHRAOUI M CAMELBEECK T | 1999 | Tectonophysics1999，309，14： | 1 |
| 10 | Trust over time in exchange relationships: meta-analysis and theory 显示文摘 | VANNESTE B S PURANAM P KRETSCHMER T K | 2014 | Strategic Management Journal2014，35，12： | 1 |
| 11 | Late Quaterna- ry earthquake-related soft-sediment deformation along the Belgian portion of the Feldbiss Fault, Lower Rhine Graben System显示文摘 | Vanneste K Meghraoui M Camelbeeck T | 1999 | Teetonophyscs1999，309，： | 1 |
| 12 | Unilateral bloody nipple discharge in a two-month-old male显示文摘 | De Praeter C De Coen K Vanneste K | 2008 | Eur J Pediatr2008，167，4： | 1 |
| 13 | Gamma paleohexaploidy in the stem 一 lineage of core eudicots :significance formads - box gene and species diversification显示文摘 | VEKEMANS D PROOST S VANNESTE K | 2012 | Molecular Biology and Evolution2012，29，12： | 1 |
| 14 | Auxin-mediated cell cycle activation during early lateral root initiation显示文摘 | HIMANEN K BOUCHERON E VANNESTE S | 2002 | Plant Cell2002，14，： | 1 |
| 15 | Auxin- mediated cell cycle activation during early lateral root initiation显示文摘 | Himanen K Boucheron E Vanneste S | 2002 | Plant Cell2002，14，： | 1 |
| 16 | Late Quaternary earthquake-related soft-sediment deformation along the Belgian portion of the feldbiss fault,lower rhine Graben system显示文摘 | VANNESTE K MEGHRAOUI M CAMELBEEC T | 1999 | Tectonophysics1999，309，： | 1 |
| 17 | Authigenic carbonates from the Darwin Mud Volcano, Gulf of Cadiz: A record of palaeo-seepage of hydrocarbon bearing fluids 显示文摘 | Vanneste H Kastner M James R H Connelly D P Fisher R E Kelly-Gerreyn B A Heeschen K Haeckel M Mills RA | 2012 | Chem Geol2012，，： | 1 |
| 18 | Auxin-mediated cell cycle activation during early lateral root initiation显示文摘 | HIMANEN K BOUCHERON E VANNESTE S | 2002 | Plant Cell2002，14，10： | 1 |
| 19 | Ethylene regulates root growth through effects on auxin biosynthesis and transport- dependent auxin distribution显示文摘 | Ruzicka K Ljung K Vanneste S Podhorska R Beeckman T Friml J Benkova E | 2007 | Plant Cell2007，19，： | 1 |
| 20 | Transcript profiling of early lateral re, or initiation 显示文摘 | Himanea K Vuylsteke M Vanneste S | 2004 | Proceedings of the National Academy of Science of the USA2004，101，14： | 1 |
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