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| 1 | 角膜胶原交联术治疗圆锥角膜的疗效和安全性研究显示文摘目的:研究角膜胶原交联术治疗圆锥角膜的疗效和安全性。方法:对2015-04/2018-08在泰国朱拉隆功国王纪念医院行角膜胶原交联术的圆锥角膜患者病历进行回顾性分析。评估术前和术后1a的视力、屈光度、角膜地形图、高阶像差(HOA)、地形图参数和角膜密度。根据患者年龄是否小于24和30岁、基线角膜最大曲率(Kmax)是否小于55 D、基线最佳矫正视力(BCVA)是否小于0.3 LogMAR分组评估年龄、基线Kmax和BCVA对手术疗效的影响。分析术前Kmax、Kmean、平均等效球镜度数(MRSE)、视力、角膜最薄点厚度值、Kmax的变化以及相关参数的变化与角膜密度测量值变化之间的关系。P<0.05具有统计学意义。结果:共155例患者185眼纳入研究,其中119例男性,36例女性。根据Amsler-Krumeich进行分类,1期和2期占优势(分别为37.84%和35.14%)。术后1a,平均裸眼视力(UCVA)提高0.1 LogMAR(P<0.05)。与基线BCVA较好组(术前BCVA<0.3 LogMAR)相比,基线BCVA较差组(术前BCVA≥0.3 LogMAR)术后BCVA改善大于0.2 LogMAR的眼数较多(78.26%vs 21.74%,P<0.05)。平均Kmax比基线下降2.36 D(P<0.05)。术前Kmax≥55 D的患眼术后Kmax下降超过2.0 D的眼数占比73%。距角膜顶点6 mm处角膜HOA下降0.40(P<0.05)。术后1mo~1a,0~6 mm区角膜密度测量值持续增加。术后1a,角膜密度的增加与最薄点厚度的减少呈线性相关。表面变异指数、高度非对称性指数、圆锥角膜指数、高度轴偏心指数在术后1a时下降(P<0.05)。术后1a,手术成功率为90.24%。术后1wk、1、3、6mo、1a角膜混浊发生率分别为11.35%、30.27%、15.67%、10.27%、2.16%。无角膜水肿发生,但有1例无菌性角膜炎患者。结论:角膜胶原交联术可有效治疗圆锥角膜,使角膜变平、重塑,提高视力、HOA和角膜形态指数,晚期圆锥角膜Kmax也明显降低。 | Yonrawee Piyacomn Ngamjit Kasetsuwan Vilavun Puangsricharern Usanee Reinprayoon Vannarut Satitpitakul Patchima Chantaren | 2021 | 国际眼科杂志2021，21，7： | 5 |
| 2 | Vancomycin clearance during continuous venovenous haemofiltration in critically ill patients显示文摘 | Weerachai Chaijamorn Arnurai Jitsurong Kamonthip Wiwattanawongsa Usanee Wanakamanee Phongsak Dandecha | 2011 | International Journal of Antimicrobial Agents2011，，2： | 1 |
| 3 | Strong association between HLA-B*5801 and allopurinol-induced Stevens–Johnson syndrome and toxic epidermal necrolysis in a Thai population显示文摘 | Wichittra Tassaneeyakul Thawinee Jantararoungtong Pei Chen Pao-Yu Lin Somsak Tiamkao Usanee Khunarkornsiri Pachadaporn Chucherd Parinya Konyoung Suda Vannaprasaht Charoen Choonhakarn Pornrith Pisuttimarn Alisara Sangviroon Wongwiwat Tassaneeyakul | 2009 | Pharmacogenetics and Genomics2009，，9： | 1 |
| 4 | Mutagenicity and Human Chromosomal Ef- fect of Stevioside, a Sweetener from Stevia rebaudiana Bertoni显示文摘 | MAITREE SUTTAJIT uSANEE VINITKEKKAUMNUEN UM- NAT MEEVETEE | 1993 | En- vironmental Health Perspectives1993，，101： | 1 |
| 5 | Interferon-gamma release assays in tuberculous uveitis:a comprehensive review显示文摘·Tuberculous uveitis(TBU)comprises a broad clinical spectrum of ocular manifestations,making its diagnosis challenging.Ophthalmologists usually require evidence from investigations to confirm or support a clinical diagnosis of TBU.Since direct isolation of the causative organism from ocular specimens has limitations owing to the small volume of the ocular specimens,resultant test positivities are low in yield.Immunodiagnostic tests,including the tuberculin skin test and interferon-gamma release assays(IGRAs),can help support a clinical diagnosis of TBU.Unlike the tuberculin skin test,IGRAs are in vitro tests that require a single visit and are not affected by prior Bacillus Calmette-Guerin vaccination.Currently,available IGRAs consist of different techniques and interpretation methods.Moreover,newer generations have been developed to improve the sensitivity and ability to detect active tuberculosis.This narrative review collates salient practice points as a reference for general ophthalmologists,such as evidence for the utilization of IGRAs in patients with suspected TBU,and summarizes basic knowledge and details of clinical applications of these tests in a clinical setting. | Usanee Tungsattayathitthan Sutasinee Boonsopon Nattaporn Tesavibul Tararaj Dharakul Pitipol Choopong | 2022 | International Journal of Ophthalmology(English edition)2022，15，9： | 0 |
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