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| 1 | Pulmonary embolism after arterial chemoembolization for hepatocellular carcinoma: An autopsy case report显示文摘We report an extremely rare case of pulmonary lipiodol embolism with acute respiratory distress syndrome(ARDS) after transcatheter arterial chemoembolization(TACE) for hepatocellular carcinoma(HCC). A 77-yearold man who was diagnosed with a huge HCC wasadmitted for TACE. Immediately after the procedure, this patient experienced severe dyspnea. We suspected that his symptoms were associated with a pulmonary lipiodol embolism after TACE, and we began intensive treatment. However, his condition did not improve, and he died on the following day. A subsequent autopsy revealed that the cause of death was ARDS due to pulmonary lipiodol embolism. No cases have been previously reported for which an autopsy was performed to explain the most probable mechanism of pulmonary lipiodol embolism; thus, ours is the first report for such a rare case. | Keiichi Hatamaru Shunjiro Azuma Takuji Akamatsu Takeshi Seta Shunji Urai Yoshito Uenoyama Yukitaka Yamashita Kazuo Ono | 2015 | World Journal of Gastroenterology2015，21，4： | 5 |
| 2 | Focal adhesion kinase and Src phosphorylations in HGF-induced proliferation and invasion of human cholangiocarcinoma cell line, HuCCA-1显示文摘AIM: To study the role of focal adhesion kinase (FAK) and its association with Src in hepatocyte growth factor (HGF)-induced cell signaling in cholangiocarcinoma progression.METHODS: Previously isolated HuCCA-1 cells were re-characterized by immunofluorescent staining and reverse transcriptase-polymerase chain reaction assay for the expression of cytokeratin 19, HGF and c-Met mRNA. Cultured HuCCA-1 cells were treated with HGF and determined for cell proliferation and invasion effects by MTT and invasion assays. Western blotting, immunoprecipitation, and co-immunoprecipitation were also performed to study the phosphorylation and interaction of FAK and Src. A novel Src inhibitor (AZM555130) was applied in cultures to investigate the effects on FAK phosphorylation inhibition and on cell proliferation and invasion.RESULTS: HGF enhanced HuCCA-1 cell proliferation and invasion by mediating FAK and Src phosphorylations.FAK-Src interaction occurred in a time-dependent manner that Src was proved to be an upstream signaling molecule to FAK. The inhibitor to Src decreased FAK phosphorylation level in correlation with the reduction of cell proliferation and invasion.CONCLUSION: FAK plays a significant role in signaling pathway of HGF-responsive cell line derived from cholangiocarcinoma. Autophosphorylated Src, induced by HGF, mediates Src kinase activation, which subsequently phosphorylates its substrate, FAK, and signals to cell proliferation and invasion. | Urai Pongchairerk Jun-Lin Guan Vijittra Leardkamolkarn | 2005 | World Journal of Gastroenterology2005，11，37： | 5 |
| 3 | Probing the molecular program of apoptosis by cancer chemopreventive agents显示文摘 | Fesus I Szondy Z Uray I | 1995 | J Cell Biochem Suppl1995，22，： | 1 |
| 4 | Effect of cooling after human cardiac arrest on myocardial infarct size显示文摘 | Koreny M Sterz F Uray T | | 0，，01： | 1 |
| 5 | The internal geometry of salt structures - A first look using 3D seismic data from the Zechstein of the Netherlands 显示文摘 | VAN G H URAI J L DE K M | 2011 | Journal of Structural Geology2011，33，3： | 1 |
| 6 | 3D seismic study of complex intra- salt deformation: an example from the Upper Permian Zechstein 3 stringer, western Dutch offshore显示文摘 | STROZYK F VAN G H URAI J L | 2012 | Geological Society London Special Publications2012，363，1： | 1 |
| 7 | Clay smear in normal fault zones: The effect of multilayers and clay cementation in water-saturated model experiments显示文摘 | SCHMATZA J VROLIJK P J URAI J L | 2010 | Journal of Structural Geology2010，32，： | 1 |
| 8 | Development of a Direct Drive Servo Valve Using a Giant Magnetostrictive Actuator 显示文摘 | Takahiro Urai | 1993 | Fluid Power1993，，： | 1 |
| 9 | Vorticity and strain analysis using Mohr diagrams显示文摘 | PASSCHIER C W URAI J L | 1988 | Journal of Structural Geology1988，10，： | 1 |
| 10 | Dealkylation reaction of acetals, phosphon- ate, and phosphate esters with chlorotrimeth- ylsilane/metal halide reagent in acetonitrile, and its application to the synthesis of phosphonic acids and vinyl phosphates 显示文摘 | Tsuyoshi Morita Yoshiki Okamoto Hiroshi Sak- urai | 1981 | Bull Chem Japan1981，54，1： | 1 |
| 11 | comparative analysis of linear an- tibody epitopes on human and mycobacterial 60-kDa heat shock pro- teins using samples of healthy blood donors 显示文摘 | Uray K Hudecz F Fust G | 2003 | Int Immunol2003，15，10： | 1 |
| 12 | Effects of galvanizing and galvannealing conditions on powdering characteristics of galvannealed steel sheet 显示文摘 | Urai M Arimura M Sakai H | 1996 | Kobelco Technology Review1996，19，： | 1 |
| 13 | Extracellular polysaccharides of Rhodococcus rhodochrous S-2 stimulate the degradation of components in crude oil by indigeous marine bacteria 显示文摘 | IWABUCHI N SUNAIRI M URAI M | 2002 | Applied and Environment Microbiology2002，68，5： | 1 |
| 14 | Comparative analysis of linear antibody epitopes on human and mycobaeterial 60-kDa heat shock proteins using samples of healthy blood donors 显示文摘 | Uray K Hudecz F Fust G | 2003 | Int Immunol2003，15，： | 1 |
| 15 | Development of a common-rail proportional injector controlled by a tandem arrayed giant magnetostrictive actuator显示文摘 | Tanaka H Sato Y Urai T | | 0，，22： | 1 |
| 16 | Synthesis of 4-methoxy-2,3,5-trimethylpyridine: a specific building block for compounds with gastric-acid inhibiting activity 显示文摘 | Mittelbach M Schmidt HW Uray G | 1988 | Acta Chem Scand B1988，42，8： | 1 |
| 17 | Microstructural observations on natural syntectonic fibrous veins: Implications for the growth process显示文摘 | HILGERS C URAI J L | 2002 | Tectonophysics2002，352，3： | 1 |
| 18 | Vorticity and strain analysis using Mohr diagrams显示文摘 | Urai J L | 1988 | J Struct Geol1988，10，8： | 1 |
| 19 | Estradiol down-regulates CD36 ex- pression in human breast cancer cells显示文摘 | Uray IP Liang Y Hyder SM | 2004 | Cancer Lett2004，207，1： | 1 |
| 20 | An apparatus to experimentally model the dynamics of ductile shear zone显示文摘 | Bons P D Urai J L | 1996 | Tectonophysics1996，256，： | 1 |
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