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| 1 | “Autoinflammatory psoriasis”-genetics and biology of pustular psoriasis显示文摘Psoriasis is a chronic inflammatory skin condition that has a fairly wide range of clinical presentations.Plaque psoriasis,which is the most common manifestation of psoriasis,is located on one end of the spectrum,dominated by adaptive immune responses,whereas the rarer pustular psoriasis lies on the opposite end,dominated by innate and autoinflammatory immune responses.In recent years,genetic studies have identified six genetic variants that predispose to pustular psoriasis,and these have highlighted the role of IL-36 cytokines as central to pustular psoriasis pathogenesis.In this review,we discuss the presentation and clinical subtypes of pustular psoriasis,contribution of genetic predisposing variants,critical role of the IL-36 family of cytokines in disease pathophysiology,and treatment perspectives for pustular psoriasis.We further outline the application of appropriate mouse models for the study of pustular psoriasis and address the outstanding questions and issues related to our understanding of the mechanisms involved in pustular psoriasis. | Ranjitha Uppala Lam C.Tsoi Paul W.Harms Bo Wang Allison C.Billi Emanual Maverakis J.Michelle Kahlenberg Nicole L.Ward Johann E.Gudjonsson | 2021 | Cellular & Molecular Immunology2021，18，2： | 7 |
| 2 | The ERA - Interim reanalysis: configuration and performance of the data assimilation system显示文摘 | Dee D P Uppala S M Simmons A J | 2011 | Q J R Meteorol Soc2011，137，： | 1 |
| 3 | The ERA-40 re-analysis显示文摘 | UPPALA S M K:LLBERG P W SIMMONS A J | 2005 | Q J Roy Meteor Soc2005，131，612： | 1 |
| 4 | ECMWF reanalysis, 1957-2001, ERA40显示文摘 | UPPALA S | 2002 | ERA40 Project Report Series2002，3，1： | 1 |
| 5 | The ERA-Interim reanalysis: Configuration and performance of the data assimilation system 显示文摘 | DEE D P UPPALA S M SIMMONS A J | 2011 | Q J R Meteo Soc2011，137，656： | 1 |
| 6 | The ERA-Interim reanalysis:configuration and performance of the data assimilation system显示文摘 | Dee D P Uppala S M Simmons A J | 2011 | Quarterly Journal of the Royal Meteorological Society2011，137，656： | 1 |
| 7 | The ERA- 4,0 re analysis 显示文摘 | Uppala S M P W Kallberg A J Simmons | 2005 | Quarterly Journal of the Royal Meteoroogical Society2005，131，612： | 1 |
| 8 | ERA-40: ECMWF 45 year reanalysis of the global atmosphere and surface conditions 1957-2002 显示文摘 | Uppala S Kallberg P Angeles H | 2004 | ECMWF Newsletter Meteorology2004，101，： | 1 |
| 9 | The ERA-40 Re-Analysis显示文摘 | UPPALA S M KALLBERG P W SIMMONS A J | 2005 | Quart J Roy Meteor Soc2005，131，612： | 1 |
| 10 | The ERA-40 re-analysis显示文摘 | Uppala S M Kallberg P W Simmons A J | 2005 | Quarterly Journal of the Royal Meteorological Society2005，131，： | 1 |
| 11 | Clinical outcomes after utilizing surviving sepsis campaign in children with septic shock and prognostic value of initial plasma NT-pro BNP显示文摘 | Samransamruajkit R Uppala R Pongsanon K | 2014 | Indian J Crit Care Med2014，18，2： | 1 |
| 12 | The ERA-Interim reanalysis: configuration and performance of the data assimilation system显示文摘 | DEE D P UPPALA S M SIMMONS A J | 2011 | Quarterly Journal of the Royal Meteorological Society2011，137，1： | 1 |
| 13 | 2D difference gel analysis of protein expression on the anti-proliferative effect of lycopene on breast cancer cells显示文摘 | DISSMORE T UPPALA P T LAU B H S | 2004 | Journal of the American Fietetic Association2004，104，2： | 1 |
| 14 | New Prediction Method of Cloud Attenuation显示文摘 | Salonen E Uppala S | 1991 | Electronics Letters1991，27，12： | 1 |
| 15 | The ERA-40 re-analysis显示文摘 | Uppala S M Kallberg P W Simmons A J | 2005 | Quarterly Journal of the Royal Meteorological Society2005，131，： | 1 |
| 16 | The ERA-40 re-analysis显示文摘 | Uppala S M Kallberg P W Simmons A J | 2005 | Quarterly Journal of the Royal Meteorological Society2005，131，612： | 1 |
| 17 | The ERA-Interim reanalysis: Configuration and performance of the data assimilation system显示文摘 | Dee D P Uppala S M Simmons A J | 2011 | Quarterly Journal of the Royal Meteorological Society2011，137，： | 1 |
| 18 | The ERA-40 re-analysis显示文摘 | Uppala S M Kollberg P W Simmons A J | 2005 | Quarterly Journal of the Royal Meteorological So- ciety2005，131，： | 1 |
| 19 | The ERA-40 re- analysis 显示文摘 | Uppala S M Kllerg P W Simmons A J | 2005 | Quarterly Journal of the Royal Meteorological Soci- ety2005，131，612： | 1 |
| 20 | The ERA-40 re-analysis 显示文摘 | UPPALA S M KALLBERG P W SIMMONS A J | 2005 | Quart J Roy Meteor Soc2005，，131： | 1 |
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