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| 1 | Eukaryotic nucleotide excision repair: from understanding mechanisms to influencing biology显示文摘笨重脱氧核糖核酸的修理由小径是的核苷酸切除修理(NER ) 使内收更万用的脱氧核糖核酸之一为脱氧核糖核酸损害的移动修理小径。有 NER 小径,全球 genomic-NER (GG-NER ) 和联合抄写的 NER (TC-NER ) 的二个子集,它仅仅在包含脱氧核糖核酸损害的识别的步不同。损坏的后面的识别,亚小径然后为充满的切口 / 切除步骤和结扎步骤收敛。这评论将集中于 NER 的 GGR 亚小径,当 TCR 亚小径将在这个问题在另一篇文章被盖住时。到修理的 NER 小径的能力一个宽数组使内收部分地,茎在影响人的生理的回答和事件的一个同等地宽的数组的 NER 损坏脱氧核糖核酸和结果从涉及起始的识别的机制走。在这评论, carcinogenesis 上的 NER 的影响,神经病学的功能,到环境因素的敏感和到癌症的敏感,治疗学将被讨论。在过去的 40 年在我们 NER 小径的理解产生的知识从进展,以及从体质研究和参予这条小径的蛋白质和酶的结构的分析导致了动物模型系统,哺乳动物的遗传和试管内生物化学的领域。每研究的这些大街显著地作出贡献到我们 NER 小径怎么并且怎么工作的理解在 NER 活动的改变,积极、否定,影响人生物学。 | Sarah C Shuck Emily A Short John J Turchi | 2008 | Cell Research2008,18,1: | 7 |
| 2 | Beeswax:A minireview of its antimicrobial activity and its application in medicine显示文摘Beeswax is the substance that forms the structure of a honeycomb; the bees secrete wax to build the honeycombs where to store honey.Thanks to its rich hydrophobic protective properties,the beeswax is in fact present within cosmetics and body products.Also,beeswax is used in the food industry:as a film to wrap cheese for maturing or as a food additive(E901) to give shine to the products.Exactly as the honey which it contains,beeswax is also characterized by several therapeutic properties of great interest to us; it is thought to be particularly effective in healing bruises,inflammation and burns.Recently,the interest of researchers has moved even on antimicrobial properties of beeswax although there are still few studies in the literature focused only on the action of beeswax.The few studies showed an anitimicrobic effectiveness of beeswax against overall Staphylococcus aureus,Salmonella enterica,Candida albicans and Aspergillus niger; these inhibitory effects are enhanced synergistically with other natural products such as honey or olive oil.This minireview aims to be a collection of major scientific works that have considered the antimicrobial activity of beeswax alone or in combination with other natural products in recent years. | Filippo Fratini Giovanni Cilia Barbara Turchi Antonio Felicioli | 2016 | Asian Pacific Journal of Tropical Medicine2016,9,9: | 3 |
| 3 | Priorities and needs for research on urban interventions targeting vector-borne diseases: rapid review of scoping and systematic reviews显示文摘This paper highlights the critical importance of evidence on vector-borne diseases(VBD)prevention and control interventions in urban settings when assessing current and future needs,with a view to setting policy priorities that promote inclusive and equitable urban health services.Research should produce knowledge about policies and interventions that are intended to control and prevent VBDs at the population level and to reduce inequities.Such interventions include policy,program,and resource distribution approaches that address the social determinants of health and exert influence at organizational and system levels. | Clara Bermudez-Tamayo Olive Mukamana Mabel Carabali Lyda Osorio Florence Fournet Kounbobr Roch Dabiré Celina Turchi Marteli Adolfo Contreras Valéry Ridde | 2016 | Infectious Diseases of Poverty2016,5,1: | 3 |
| 4 | Scoping review on vector-borne diseases in urban areas:transmission dynamics,vectorial capacity and co-infection显示文摘Background:Transmission dynamics,vectorial capacity,and co-infections have substantial impacts on vector-borne diseases(VBDs)affecting urban and suburban populations.Reviewing key factors can provide insight into priority research areas and offer suggestions for potential interventions.Main body:Through a scoping review,we identify knowledge gaps on transmission dynamics,vectorial capacity,and co-infections regarding VBDs in urban areas.Peer-reviewed and grey literature published between 2000 and 2016 was searched.We screened abstracts and full texts to select studies.Using an extraction grid,we retrieved general data,results,lessons learned and recommendations,future research avenues,and practice implications.We classified studies by VBD and country/continent and identified relevant knowledge gaps.Of 773 articles selected for full-text screening,50 were included in the review:23 based on research in the Americas,15 in Asia,10 in Africa,and one each in Europe and Australia.The largest body of evidence concerning VBD epidemiology in urban areas concerned dengue and malaria.Other arboviruses covered included chikungunya and West Nile virus,other parasitic diseases such as leishmaniasis and trypanosomiasis,and bacterial rickettsiosis and plague.Most articles retrieved in our review combined transmission dynamics and vectorial capacity;only two combined transmission dynamics and co-infection.The review identified significant knowledge gaps on the role of asymptomatic individuals,the effects of co-infection and other host factors,and the impacts of climatic,environmental,and socioeconomic factors on VBD transmission in urban areas.Limitations included the trade-off from narrowing the search strategy(missing out on classical modelling studies),a lack of studies on co-infections,most studies being only descriptive,and few offering concrete public health recommendations.More research is needed on transmission risk in homes and workplaces,given increasingly dynamic and mobile populations.The lack of studies on co-infection hampers monitoring of infections transmitted by the same vector.Conclusions:Strengthening VBD surveillance and control,particularly in asymptomatic cases and mobile populations,as well as using early warning tools to predict increasing transmission,were key strategies identified for public health policy and practice. | Marcus Eder Fanny Cortes Noemia Teixeira de Siqueira Filha Giovanny Vinicius Araujo de Franca Stephanie Degroote Cynthia Braga Valery Ridde Celina Maria Turchi Martelli | 2018 | Infectious Diseases of Poverty2018,7,1: | 2 |
| 5 | Analytical and clinical performance of an automated chemiluminescent immunoassay for direct renin measurement:comparison with PRA and aldosterone assays显示文摘 | Iervasi A Zucchelli GC Turchi S | 2005 | Immunoanalyse & Biologie Spccialisee2005,20,4: | 1 |
| 6 | Activated Vgamma9Vdelta2Tcells trigger granulocyte functions via MCP-2release显示文摘 | Agrati C Cimini E Sacchi A Bordoni V Gioia C Casetti R Turchi F Tripodi M Martini F | 2009 | J Immunol2009,182,1: | 1 |
| 7 | Effects of epi- dural analgesia on labor length, instrumental delivery, and neonatal short-term outcome显示文摘 | Hasegawa J Farina A Turchi G | 2013 | J Anest2013,27,1: | 1 |
| 8 | Mixed reactant photocatalysis:intermediates and mutual rate inhibition 显示文摘 | Craig S Turchi David F Ollis | 1989 | Catal1989,,119: | 1 |
| 9 | Photocatalytic degradation of organic water contaminants:Mechanisms involving hydroxyl radical attack显示文摘 | Turchi C S Ollis D F | 1990 | Journal of Catalysis1990,122,1: | 1 |
| 10 | Increased MAPK signaling during in vitro muscle wounding 显示文摘 | Yeow K Cabane C Turchi L | 2002 | Biochem Biophys Res Commun2002,293,1: | 1 |
| 11 | Heterogeneous photocatalytic for water purification: contaminant mineralization kinetics and elementary reactor analysis显示文摘 | Ollis D F Turchi C | 1990 | Environ Prog1990,9,4: | 1 |
| 12 | ATF3 and pl5PAF are novel gatekeepers of genomic integrity upon UV stress显示文摘 | Turchi L Fareh M Aberdam E | 2009 | Cell Death Differ2009,16,5: | 1 |
| 13 | Cortical acetylcholine and processing capacity: Effects of cortical cholinergic deafferentation on crossmodal divided attention in rats 显示文摘 | Turchi Janita Sarter Martin | 1997 | Cognitive Brain Research1997,6,2: | 1 |
| 14 | Photo Catalytic Degradation Contaminants Mechanisms Involving Hydroxyl Radical Attack显示文摘 | CRAIG S TURCHI DAVID F OLLIS | 1990 | journal of catalysis1990,122,: | 1 |
| 15 | Cisplatin-induced apoptosis pro ceeds by caspase-3-dependent and independent pathways in cisplatin-resistant and -sensitive human ovarian cancer cell lines显示文摘 | Henkels KM Turchi JJ | 1999 | Cancer Res1999,59,13: | 1 |
| 16 | Primary aldosteronism and essential hypertension: assessment of cardiovascular risk at diagnosis and after treatment显示文摘 | Turchi F Ronconi V di Tizio V | 2014 | Nutr Metab Cardiovasc Dis2014,24,5: | 1 |
| 17 | Heterogeneous photocatlytic for water purification:contaminant mineralization kinetics and elementary reactor analysis显示文摘 | Ollis D F Turchi C | 1990 | Environ Prog1990,9,4: | 1 |
| 18 | Aldosterone as a key mediator of the cardiometaholic syndrome in primary aldosteron- ism : an observational study 显示文摘 | Giacchetti G Ronconi V Turchi F | 2007 | J Hypertens2007,25,1: | 1 |
| 19 | Photocatalytie degradation of organic water contaminants : mechanisms involving hydroxyl radical attack 显示文摘 | Turchi C S Ollis D F | 1990 | JCatal1990,122,1: | 1 |
| 20 | Photocatalytic Degradation of Organic Water Contaminants: Mechanisms Involving Hydroxyl Radical Attack 显示文摘 | Turchi C S Ollis D F | 1990 | Journal of Catalysis1990,122,1: | 1 |