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49篇 您的检索式:作者名="Tuncel N"
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1Delaying surgery after neoadjuvant chemoradiotherapy improves prognosis of rectal cancer显示文摘AIM To investigate the prognostic effect of a delayed interval between neoadjuvant chemoradiotherapy(CRT) and surgery in locally advanced rectal cancer.METHODS We evaluated 87 patients with locally advanced mid-or distal rectal cancer undergoing total mesorectal excision following an interval period after neoadjuvant CRT at ?i?li Hamidiye Etfal Training and Research Hospital,Istanbul between January 2009 and January 2014.Patients were divided into two groups according to the intervalbefore surgery: < 8 wk(group Ⅰ) and ≥ 8 wk(group Ⅱ).Data related to patients,cancer characteristics and pathological examination were collected and analyzed.RESULTS When the distribution of timing between group Ⅰ(n = 45) and group Ⅱ(n = 42) was viewed,comparison of interval periods(median ± SD) of groups showed a significant difference of as 5 ± 1.28 wk in group Ⅰ and 10.1 ± 2.2 wk in group Ⅱ(P < 0.001).The median follow-up period for all patients was 34.5(9.9-81) mo.group Ⅱ had significantly higher rates of pathological complete response(p CR) than group Ⅰ had(19% vs 8.9%,P = 0.002).Rate of tumor regression grade(TRG) poor response was 44.4% in group Ⅰ and 9.5% in group Ⅱ(P < 0.002).A poor pathological response was associated with worse disease-free survival(P = 0.009).The interval time did not show any association with local recurrence(P = 0.79).CONCLUSION Delaying the neoadjuvant CRT-surgery interval may provide nodal down-staging,improve p CR rate,and decrease the rate of TRG poor response.Mehmet Mihmanli Esin Kabul Gürbulak Ismail Ethem Akgün Mustafa Fevzi Celayir Pinar Yazici Deniz Tuncel Tuba Tülin Bek Ayhan Oz Sinan Omeroglu 2016World Journal of Gastrointestinal Oncology2016,8,9:3
2Vasoactive intestinal peptide in- hibits degranulation and changes granular content of mast cells:a po- tential therapeutic strategy in controlling shock 显示文摘Tuncel N Tarol F Sahinturk V 2000Peptides2000,21,1:1
3Behavior ofPVA fiber-reinforced cementitious composites under static and impact Eexural effects显示文摘ATAHAN H N TUNCEL E Y PEKMEZCI B Y 2013Journal of Materials in Civil Engineering2013,25,10:1
4Changes in applicator positions and dose distribution between high dose rate hrachytherapy fractions in cervix carcinoma patients receiving definitive radiotherapy显示文摘Garipagaoglu M Tuncel N Dalmaz MC 2006Br J Radiol2006,79,942:1
5Geometric and dosemetric variations of IURU bladder and return reference points in vaginal cuff brachytherapy using ovoids显示文摘Garipagaoglu M Tuncel N Voseoglu FG 2004Radiat Biol phys2004,58,5:1
6Protective effect of vasoactive intestinal peptide on testicular torsion-detorsion injury: association with heparin-containing mast cells显示文摘Can C Tore F Tuncel N 2004Urology2004,63,1:1
7Vasoactive intestinal peptide inhibits degranulation and changes granu-lar content of mast cells: a potential thera-peutic strategy in controlling septic shock显示文摘Tuncel N Tore F Sahinturk V 2000Peptides2000,21,:1
8The protective effect of vasoactive intestinal peptide (VIP) on stress-induced gastric ulceration in rats显示文摘Tuncel N Erkasap M Sahinturk V 1998Ann NY Acad Sci1998,865,:1
9Geometric and dosimetric variations of ICRU bladder and rectum reference points in vaginal cuff brachytherapy using ovoids 显示文摘Garipagaoglu M Tuncel N Koseoglu FG 2004Int J Radiat Oncol Biol Phys2004,58,5:1
10Vasoactive intestinal peptide inhibits degranulation and changes granular content of mast cells:a potential therapeutic strategy in controlling septic shock 显示文摘TUNCEL N TORE F SAHINTURK V V 2000Peptides2000,21,1:1
11Infrared stabilization of rice bran and its effects onγ-oryzanol content,tocopherols and fatty acid composition显示文摘YILMAZ N TUNCEL N-B KOCABIYIK H 2014Journal of the Science of Food and Agriculture2014,94,8:1
12Vasoactive intestinal peptide inhibits degranulation and changes granular content of mast cells:a potential therapeutic strategy in controlling septic shock显示文摘Tuncel N Tore F Sahinturk V 2000Peptides2000,21,1:1
13Vasoactive intestinal peptide (VIP) treatment of Parkinsonian rats increases thalamic gamma-aminobutyric acid (GABA) levels and alters the release of nerve growth factor (NGF) by mast cells 显示文摘Korkmaz OT Tuncel N Tuncel M 2010J Mol Neurosci2010,41,:1
14Effects of vasoacrive intestinal peptide and naloxone combination on urinary N-acetyl-beta-D-glucosaminidase level and kidney histology of rats exposed to severe hemorrhage显示文摘Akin MZ Tuncel N Gurer F 1993Pharmacology1993,47,3:1
15Preparation and characterization of thermosensitive submicron particles for gene delivery 显示文摘Ozdemir N Tuncel A Kang M 2006J Nanosei Nanoteehnol2006,,6:1
16Passage of VIP/PACAP/secretin family across the blood-brain barrier: therapeutic effects显示文摘Dogrukol-Ak D Tore F Tuncel N 2004Curr Pharm Des2004,10,12:1
17Vasoactive intestinal peptide inhibits degranulation and changes granular content of mast cells:a potential therapeutic strategy in controlling septic shock显示文摘Tuncel N T(o)re F Sahintürk V 0,,01:1
18Infrared stabilization of rice bran and its effects on gamma-oryzanol content, tocopherols and fatty acid composition 显示文摘YILMAZ N TUNCEL N B KOCABIYIK H 2014Journal of the Science of Food and Agriculture2014,94,18:1
19The effect of infrared stabilisation on B vitamins, phenolics and antioxidants in rice bran 显示文摘YILMAZ N TUNCEL N B 2015International Journal of Food Science & Technology2015,50,1:1
20The protective effect of vasoactive intestinal peptide (VIP) on stress-induced gastric ulceration in rats 显示文摘Tuncel N Erkasap N Sahinturk V 1998Ann N Y Acad Sci1998,865,1:1
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