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| 1 | Role of genetics in the diagnosis and prognosis of Crohn's disease显示文摘Considering the epidemiological, genetic and immunological data, we can conclude that the inflammatory bowel diseases are heterogeneous disorders of multifactorial etiology in which hereditability and environment interact to produce the disease. It is probable that patients have a genetic predisposition for the development of the disease coupled with disturbances in immunoregulation. Several genes have so far been related to the diagnosis of Crohn's disease. These genes are related to innate pattern recognition receptors, to epithelial barrier homeostasis and maintenance of epithelial barrier integrity, to autophagy and to lymphocyte differentiation. So far, the strongest and most replicated associations with Crohn's disease have been demonstrated with NOD2 , IL23R and ATG16L1 genes. Many genes have so far been implicated in the prognosis of Crohn's disease and many attempts have been made for classification of genetic profiles in Crohn's disease.CARD15 seems to be not only a susceptibility gene, but also a disease-modifier gene for Crohn's disease. Enriching our understanding of Crohn's disease genetics is of value, but when combining genetic data with functional data the outcome could be of major importance to clinicians. | Epameinondas V Tsianos Konstantinos H Katantions Vasileios E Tsianos | 2011 | World Journal of Gastroenterology2011，17，48： | 8 |
| 2 | Role of genetics in the diagnosis and prognosis of Crohn's disease显示文摘Considering epidemiological,genetic and immunological data,we can conclude that the inflammatory bowel diseases are heterogeneous disorders of multifactorial etiology in which hereditability and environment interact to produce the disease.It is probable that patients have a genetic predisposition for the development of the disease coupled with disturbances in immunoregulation.Several genes have been so far related to the diagnosis of Crohn's disease.Those genes are related to innate pattern recognition receptors,to epithelial barrier homeostasis and maintenance of epithelial barrier integrity,to autophagy and to lymphocyte differentiation.So far,the most strong and replicated associations with Crohn's disease have been done with NOD2,IL23R and ATG16L1 genes.Many genes have so far been implicated in prognosis of Crohn's disease and many attempts have been made to classify genetic profiles in Crohn's disease.CARD15 seems not only a susceptibility gene,but also a disease-modifier gene for Crohn's disease.Enriching our understanding on Crohn's disease genetics is important but when combining genetic data with functional data the outcome could be of major importance to clinicians. | Epameinondas V Tsianos Konstantinos H Katsanos Vasileios E Tsianos | 2012 | World Journal of Gastroenterology2012，18，2： | 3 |
| 3 | Brocellosis 显示文摘 | Pappas G Akritidis N Bosikovski M and Tsianos E | 2005 | N Engl J Med2005，352，： | 1 |
| 4 | Effective treatments in the management of brucellosis显示文摘 | Pappas G Akritidis N Tsianos E | 2005 | Expert Opin Pharmacother2005，6，2： | 1 |
| 5 | Sampling-based robot motion planning:towards realistic applications显示文摘 | TSIANOS K I SUCAN I A KAVRAKI L E | 2007 | Computer Science Review2007，1，1： | 1 |
| 6 | CT features of gastric lym- phoma 显示文摘 | Gossios K Katsimbri P Tsianos E | 2000 | Eur Radiol2000，10，3： | 1 |
| 7 | Effective treatments in the management of brucellosis 显示文摘 | Pappas G Akritidis N Tsianos E | 2005 | Expert Opin Pharmacother2005，6，2： | 1 |
| 8 | Effective treatments in the management of brucellosis 显示文摘 | Pappas G Akritidis N Tsianos E | 2005 | Expert Opin Pharmacother2005，6，： | 1 |
| 9 | CT features of gastric lympho- ma 显示文摘 | Gossios K Katsimbri P Tsianos E | 2000 | Eur Radio12000，10，3： | 1 |
| 10 | Usefulness of the non-distension of the stomath in the evaluation of perigastric invasion in advanced gastric cancer by CT显示文摘 | Cossios K Tsianos E Prassopoulos P | 1998 | Eur J Radiol1998，29，1： | 1 |
| 11 | CT features of gastric lym- phoma 显示文摘 | Gossios K Katsimbri P Tsianos E | 2000 | Eur Radio12000，10，3： | 1 |
| 12 | Usefulness of the non-distension of the stomath in the evaluation of perigastric invasion in advanced gastric cancer by CT显示文摘 | Gossios K Tsianos E Prassopoulos P | 1998 | Eur J Radiol1998，29，： | 1 |
| 13 | CT fetures of gastric lymphoma显示文摘 | Gossios K Katsimbri P Tsianos E | 2000 | Eur radiol2000，10，3： | 1 |
| 14 | CT festures of gastric lymphoma 显示文摘 | Gossios K Katsimbri P Tsianos E | 2000 | Eur radiol2000，10，3： | 1 |
| 15 | Performance at altitude and angiotensin Ⅰ-converting enzyme genotype显示文摘 | Tsianos G Eleftheriou KI Hawe E | 2005 | Eur J Appl Physiol2005，93，56： | 1 |
| 16 | CT festures of gastric lymphoma 显示文摘 | Gossios K Katsimbri P Tsianos E | 2000 | Eur Radiol2000，10，3： | 1 |
| 17 | Multiple myeloma presenting with an acute bacterial infection显示文摘 | Kalambokis G N Christou L Tsianos E V | 2009 | Int J Lab Hematol2009，31，4： | 1 |
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