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| 1 | Potential role of Limosilactobacillus fermentum as a probiotic with anti-diabetic properties: A review显示文摘Oxidative stress,inflammation,and gut microbiota impairments have been implicated in the development and maintenance of diabetes mellitus.Strategies capable of recovering the community of commensal gut microbiota and controlling diabetes mellitus have increased in recent years.Some lactobacilli strains have an antioxidant and anti-inflammatory system capable of protecting against oxidative stress,inflammation,and diabetes mellitus.Experimental studies and some clinical trials have demonstrated that Limosilactobacillus fermentum strains can beneficially modulate the host antioxidant and anti-inflammatory system,resulting in the amelioration of glucose homeostasis in diabetic conditions.This review presents and discusses the currently available studies on the identification of Limosilactobacillus fermentum strains with anti-diabetic properties,their sources,range of dosage,and the intervention time in experiments with animals and clinical trials.This review strives to serve as a relevant and well-cataloged reference of Limosilactobacillus fermentum strains capable of inducing anti-diabetic effects and promoting health benefits. | Diego Cabral Lacerda Paulo César Trindade da Costa Paula Brielle Pontes Lucas Alves Carneiro dos Santos JoséPatrocínio Ribeiro Cruz Neto Cristiane Cosmo Silva Luis Vanessa Polyana de Sousa Brito JoséLuiz de Brito Alves | 2022 | World Journal of Diabetes2022，13，9： | 3 |
| 2 | Interleukin-6-174G/C polymorphism is associated with a decreased risk of type 2 diabetes in patients with chronic hepatitis C virus显示文摘BACKGROUND Chronic hepatitis C(CHC)is associated with type 2 diabetes mellitus.Although the pathogenesis remains to be elucidated,a growing evidence has suggested a role of pro-inflammatory immune response.Increased serum concentrations of Interleukin 6(IL-6)have been associated with insulin resistance,type 2 diabetes mellitus as well as advanced forms of liver disease in chronic hepatitis C infection.AIM To investigate the frequency of IL-6-174G/C(rs1800795)single nucleotide polymorphism(SNP)in CHC patients and in healthy subjects of the same ethnicity.Associations between type 2 diabetes mellitus(dependent variable)and demographic,clinical,nutritional,virological and,IL-6 genotyping data were also investigated in CHC patients.METHODS Two hundred and forty-five patients with CHC and 179 healthy control subjects(blood donors)were prospectively included.Type 2 diabetes mellitus was diagnosed according to the criteria of the American Diabetes Association.Clinical,biochemical,histological and radiological methods were used for the diagnosis of the liver disease.IL-6 polymorphism was evaluated by Taqman SNP genotyping assay.The data were analysed by logistic regression models.RESULTS Type 2 diabetes mellitus,blood hypertension and liver cirrhosis were observed in 20.8%(51/245),40.0%(98/245)and 38.4%(94/245)of the patients,respectively.The frequency of the studied IL-6 SNP did not differ between the CHC patients and controls(P=0.81)and all alleles were in Hardy-Weinberg equilibrium(P=0.38).In the multivariate analysis,type 2 diabetes mellitus was inversely associated with GC and CC genotypes of IL-6-174(OR=0.42;95%CI=0.22-0.78;P=0.006)and positively associated with blood hypertension(OR=5.56;95%CI=2.79-11.09;P<0.001).CONCLUSION This study was the first to show that GC and CC genotypes of IL-6-174 SNP are associated with a decreased risk of type 2 diabetes mellitus in patients chronically infected with hepatitis C virus.The identification of potential inflammatory mediators involved in the crosstalk between hepatitis C virus and the axis pancreas-liver remains important issues that deserve further investigations. | Cliviany Borges da Silva Diego Alves Vieira Luisa Freitas de Melo Anna Luiza Soares Chagas Adriana Dias Gomes César Lúcio Lopes de Faria Jr Rosangela Teixeira Dulciene Maria de Magalh?es Queiroz Gifone Aguiar Rocha Maria Marta Sarquis Soares Juliana Maria Trindade Bezerra Luciana Diniz Silva | 2020 | World Journal of Hepatology2020，12，4： | 2 |
| 3 | Time-dependent effects of intermittent hydrostatic pressure on aeticular chondrocyte type II collagen and aggrecan mRNA expression显示文摘 | SMITH R L LIN J TRINDADE M C | 2000 | J Reha bil Res Dev2000，37，2： | 1 |
| 4 | Bioremediationof a weathered and a recently oil-contaminated soils from Brazil:acomparison study显示文摘 | Trindade P V O Sobral L G Rizzo A C L | 2005 | Chemosphere2005，58，4： | 1 |
| 5 | Investigation of fish encephalites viruses (FEV) expression in marine ishes using DIG-labelled probes显示文摘 | Comps M Trindade M Delsert C | 1996 | Aquaculture1996，143，： | 1 |
| 6 | Body image-related cognitive fusion as a main mediational process between body-related experiences and wom- en' s quality of life显示文摘 | FERREIA C TRINDADE IA | 2015 | Eat Weight Disord2015，20，1： | 1 |
| 7 | Body image-related cogni- tive fusion as a main mediational process between body-re- lated experiences and women;s quality of life 显示文摘 | FERREIA C TRINDADE I A | 2015 | Eat Weight Disord2015，20，1： | 1 |
| 8 | Numerical model of electromagnetic stirring for continuous casting billets显示文摘 | Vilela A C F | 2002 | IEEE Transactions on Magnetics2002，38，6： | 1 |
| 9 | Evaluation of L1 and L2 minimum norm performances on EEG localizations显示文摘 | Silva C Maltez J C Trindade E | 2004 | Clinical Neurophysiology2004，115，： | 1 |
| 10 | Magnetic desulfurization of coal显示文摘 | TRINDADE S C KOLM H | 1973 | IEEE Transactions on Magnetics1973，9，3： | 1 |
| 11 | A potato tuber-expressed mRNA with homology to steroid dehydrogenases affects gibberellin levels and plant development显示文摘 | Bachem C W B Horvath B Trindade L | 2001 | The Plant Journal2001，25，6： | 1 |
| 12 | Numerical roodel of electromagnetic stirring for continuous casting billets 显示文摘 | Leonardo B Trindade Antonio C F Vilela | 2002 | IEEE Transactions on Magnetics2002，38，6： | 1 |
| 13 | Use of dialkyldithiocarbamato complexes of bismuth(III) for the preparation of nano- and microsized Bi2S3 Particles and the X-ray Crystal Structures of and 显示文摘 | Monteiro O C Nogueira H I S Trindade T | 2001 | Chem Mater2001，13，6： | 1 |
| 14 | Influence of zirconium on microstructure and toughness of low-alloy steel weld metals显示文摘 | Trindade V B Mello R S T Pay(a)o J C | | 0，，03： | 1 |
| 15 | Numerical model of electromagnetic stirring for continuous casting billets 显示文摘 | Trindade L B Vilela A C F Filho A F F | 2002 | IEEE Transactions on Magnetics2002，38，6： | 1 |
| 16 | Karhunen-Lo6ve De- composition of coupled axial/bending vibrations of beams subject to impacts显示文摘 | Trindade M A Wolter C Sampaio R | 2005 | Journal of Sound and Vibration2005，279，345： | 1 |
| 17 | Signaling Pathways for Tumor Necrosis Factor-alpha and Interleukin-6 Expression in Human Macrophages Exposed to Titanium-alloy Particulate Debris in Vitro显示文摘 | Nakashima Y Sun D H Trindade M C | 1999 | J Bone Joint Surg Am1999，81，5： | 1 |
| 18 | miR398 and miR408 are up-regulated in response to water deficit in Medicago truncatula 显示文摘 | Trindade I Capitao C Dalmay T | 2010 | Planta2010，231，3： | 1 |
| 19 | Latero-terminal neurorrhaphy without removal of the epineural sheath:experimental study in rats显示文摘 | Viterbo F Trindade J C Hoshino K | 1992 | Rev Paul Med1992，110，： | 1 |
| 20 | A potato tuberexpressed mRNA with homology to steroid dehydrogenases affects gibberellin levels and plant development显示文摘 | Bachem C W B Horvath B Trindade L | 2001 | The Plant Journal2001，25，6： | 1 |
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