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| 1 | Endoscopic management of esophageal stenosis in children:New and traditional treatments显示文摘Post-esophageal atresia anastomotic strictures and postcorrosive esophagitis are the most frequent types of cicatricial esophageal stricture. Congenital esophageal stenosis has been reported to be a rare but typical disease in children; other pediatric conditions are peptic, eosinophilic esophagitis and dystrophic recessive epidermolysis bullosa strictures. The conservative treatment of esophageal stenosis and strictures(ES) rather than surgery is a well-known strategy for children. Before planning esophageal dilation, the esophageal morphology should be assessed in detail for its length, aspect, number and level, and different conservative strategies should be chosen accordingly. Endoscopic dilators and techniques that involve different adjuvant treatment strategies have been reported and depend on the stricture's etiology, the availability of different tools and the operator's experience and preferences. Balloon and semirigid dilators are the most frequently used tools. No high-quality studies have reported on the differences in the efficacies and rates of complications associated with these two types of dilators. There is no consensus in the literature regarding the frequency of dilations or the diameter that should be achieved. The use of adjuvant treatments has been reported in cases of recalcitrant stenosis or strictures with evidence of dysphagic symptoms. Corticosteroids(either systemically or locally injected), the local application of mitomycin C, diathermy and laser ES sectioning have been reported. Some authors have suggested that stenting can reduce both the number of dilations and the treatment length. In many cases, this strategy is effective when either metallic or plastic stents are utilized. Treatment complications, such esophageal perforations, can be conservatively managed, considering surgery only in cases with severe pleural cavity involvement. In cases of stricture relapse,even if such relapses occur following the execution of well-conducted conservative strategies, surgical stricture resection and anastomosis or esophageal substitution are the only remaining options. | Luigi Dall rsquo Oglio Tamara Caldaro Francesca Foschia Simona Faraci Giovanni Federici di Abriola Francesca Rea Erminia Romeo Filippo Torroni Giulia Angelino Paola De Angelis | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，4： | 16 |
| 2 | Pediatric gastrointestinal bleeding: Perspectives from the Italian Society of Pediatric Gastroenterology显示文摘There are many causes of gastrointestinal bleeding(GIB) in children, and this condition is not rare, having a reported incidence of 6.4%. Causes vary with age, but show considerable overlap; moreover, while many of the causes in the pediatric population are similar to those in adults, some lesions are unique to children. The diagnostic approach for pediatric GIB includes definition of the etiology, localization of the bleeding site and determination of the severity of bleeding; timely and accurate diagnosis is necessary to reduce morbidity and mortality. To assist medical care providers in the evaluation and management of children with GIB, the 'Gastro-Ped Bleed Team' of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition(SIGENP) carried out a systematic search on MEDLINE via Pub Med(http://gffzz16a62c593b5540cehu0b9fo0qv0fb69cv.ffgz.tsg.suse.edu.cn/pubmed/) to identify all articles published in English from January 1990 to 2016; the following key words were used to conduct the electronic search: 'upper GIB' and 'pediatric' [all fields]; 'lower GIB' and 'pediatric' [all fields]; 'obscure GIB' and 'pediatric' [all fields]; 'GIB' and 'endoscopy' [all fields]; 'GIB' and 'therapy' [all fields]. The identified publications included articles describing randomized controlled trials, reviews, case reports, cohort studies, casecontrol studies and observational studies. References from the pertinent articles were also reviewed. This paper expresses a position statement of SIGENP that can have an immediate impact on clinical practice and for which sufficient evidence is not available in literature. The experts participating in this effort were selected according to their expertise and professional qualifications. | Claudio Romano Salvatore Oliva Stefano Martellossi Erasmo Miele Serena Arrigo Maria Giovanna Graziani Sabrina Cardile Federica Gaiani Gian Luigi de'Angelis Filippo Torroni | 2017 | World Journal of Gastroenterology2017，23，8： | 12 |
| 3 | ConservativeapproachinPeutz-JeghersSyndrome:Single-balloon enteroscopyandsmallbowelpolypectomy显示文摘AIM: To assess the usefulness of the balloon assisted enteroscopy in preventing surgical intervention in pa-tients with Peutz-Jeghers syndrome (PJS) having a small bowel large polyps. METHODS: Seven consecutive asymptomatic pts(age 15-38 years) with PJS have been collected; six under-went polypectomy using single balloon enteroscopy(Olympus SIF Q180) with antegrade approach using push and pull technique. SBE system consists of the SIF-Q180 enteroscope, an overtube balloon control unit(OBCU Olympus Balloon Control Unit) and a dispos-able silicone splinting tube with balloon(ST-SB1). All procedures were performed under general anesthesia. Previously all pts received wireless capsule endos-copy(WCE). Prophylactic polypectomy was reservedmainly in pts who had polyps > 15 mm in diameter. The balloon is inflated and deflated by a balloon control unit with a safety pressure setting range from-6.0 kPa to +5.4 kPa. Informed consent has been obtained from pts or parents for each procedure.RESULTS: Six pts underwent polypectomy of small bowel polyps; in 5 pts a large polyp > 15 mm(range 20-50 mm in diameter) was resected; in 1 patient with WCE negative, SBE was performed for previous surgi-cal resection of gastrointestinal stromal tumors. In 2 pts endoscopic clips were placed due to a polypectomy. No surgical complication have been reported. SBE with resection of small bowel large polyps in PJS pts was useful to avoid gastrointestinal bleeding and emergency laparotomy due to intestinal intussuscep-tions. No gastrointestinal tumors were found in sub-sequent enteroscopic surveillance in all seven pts. In order surveillance, all pts received WCE, upper en-doscopy, ileocolonoscopy every 2 years. No pts had extraintestinal malignant lesions. SBE was performed when WCE was positive for significant polyps(> 15 mm).CONCLUSION: The effective of prophylactic polyp-ectomy of small bowel large polyps(> 15 mm) could be the first line treatment for conservative approach in management of PJS patients. | Torroni F Romeo E Rea F De Angelis P Foschia F Faraci S Federici di Abriola G Contini AC Caldaro T Dall’Oglio L | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，7： | 7 |
| 4 | 在胰腺的 pseudocyst 的管理的 Miniprobe EUS显示文摘 Pancreatic pseudocysts(PP) arise from trauma and pancreatitis;endoscopic gastro-cyst drainage(EGCD) under endoscopic ultrasonography(EUS) in symptomatic PP is the treatment of choice.Miniprobe EUS(MEUS) allows EGCD in children.We report our experience on MEUS-EGCD in PP,reviewing 13 patients(12 children;male:female = 9:3;mean age:10 years,4 mo;one 27 years,malnourished male Belardinelli-syndrome;PP:10 post-pancreatitis,3 post-traumatic).All patients underwent ultrasonography,computed tomography and magnetic resonance imaging.Conservative treatment was the first option.MEUS EGCD was indicated for retrogastric cysts larger than 5 cm,diameter increase,symptoms or infection.EGCD(stent and/or nasogastrocystic tube) was performed after MEUS(20-MHz-miniprobe) identification of place for diathermy puncture and wire insertion.In 8 cases(61.5%),there was PP disappearance;one,surgical duodenotomy and marsupialization of retro-duodenal PP.In 4 cases(31%),there was successful MEUS-EGCD;stent removal after 3 mo.No complications and no PP relapse in 4 years of mean followup.MEUS EGCD represents an option for PP,allowing a safe and effective procedure. | Paola De Angelis Erminia Romeo Francesca Rea Filippo Torroni Tamara Caldaro Giovanni Federici di Abriola Francesca Foschia Claudia Caloisi Vincenzina Lucidi Luigi Dall’Oglio | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，5： | 3 |
| 5 | Epidemic neuropathy in Cuba not associated with mitochondrial DNA mutations found in Leber's hereditary optic neuropathy patients 显示文摘 | Newman NJ Torroni A Brown MD | 1994 | Am J Ophthalmol1994，118，： | 1 |
| 6 | Microvaseular Reconstruction of the Mandible in Irradiated Patients显示文摘 | Torroni A Gennaro P Aboh IV | 2007 | J Craniofac Surg2007，18，6： | 1 |
| 7 | Molecular dissection of the Y chromosome haplogroup EM78 (E3bla): a posteriori evaluation of a microsatellite- network based approach through six new biallelic markers 显示文摘 | Cruciani F La Fratta R Torroni A | 2006 | Hum Mutat2006，27，： | 1 |
| 8 | Mitochondrial DNA analysis in Tibet:implications for the origin of the Tibetan population and its adaptation to high altitude显示文摘 | Torroni A Miller JA Moore LG | 1994 | Am J Phys Anthropol1994，93，2： | 1 |
| 9 | Transcervieal submandibular sialoadcnectomy显示文摘 | Mustazza MC Bartoli DD | 2007 | J Craniofae Surg2007，18，3： | 1 |
| 10 | mtDNA haplogroup and frequency patterns in Europe 显示文摘 | Torroni A Richards M Macaulay V | 2000 | Am J Hum Genet2000，66，3： | 1 |
| 11 | Harvesting the fruit of the human mtDNA tree显示文摘 | Torroni A Achilli A Macaulay V | 2006 | Trends in Genetics2006，22，6： | 1 |
| 12 | Classification of European mtDNA from an analysis of three European poplations 显示文摘 | Torroni A Huoponen K Francalacci P | 1996 | Genet Soc Amer1996，144，： | 1 |
| 13 | About the ' Asian' specific 9 bp deletion of mtDNA 显示文摘 | Torroni A Petrozzi M Santolamazza P | 1995 | Am J Hum Genet1995，57，2： | 1 |
| 14 | Strictureplasty and intestinal resection: different options in complicated pediatric-onset Crohn disease显示文摘 | Erminia Romeo Vincenzo Jasonni Tamara Caldaro Arrigo Barabino Girolamo Mattioli Stefania Vignola Giovanni Federici di Abriola Paola De Angelis Alessandro Pane Filippo Torroni Francesca Rea Luigi Dall’Oglio | 2012 | Journal of Pediatric Surgery2012，，5： | 1 |
| 15 | Classification of European mtDNA from an analysis of three European poplations显示文摘 | Torroni A Huoponen K Francalacci P | 1996 | Genet Soc Amer1996，144，4： | 1 |
| 16 | Engineering and verifying agent-oriented re- quirements augmented by business constraints with B-Tropos 显示文摘 | MONTALI M TORRONI P ZANNONE N | 2011 | Autonomous Agents and Multi- Agent Systems2011，23，2： | 1 |
| 17 | Custom dynamic stent for esophageal strictures in children显示文摘 | Francesca Foschia Paola De Angelis Filippo Torroni Erminia Romeo Tamara Caldaro Giovanni Federici di Abriola Alessandro Pane Maria Stella Fiorenza Francesco De Peppo Luigi Dall’Oglio | 2011 | Journal of Pediatric Surgery2011，，5： | 1 |
| 18 | Mitochondrial DNA variants observed in alzheimer disease and parkinson disease patients显示文摘 | Shoffner JM Brown MD Torroni A | 1993 | Genomics1993，17，1： | 1 |
| 19 | Southeast Asian Mitochondrial DNA Analysis Reveals Genetic Continuity of Ancient Mongoloid Migrations显示文摘 | Ballinger S W Schurr T G Torroni A | 1992 | Genetics1992，130，： | 1 |
| 20 | Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients显示文摘 | Shoffner JM Brown MD Torroni A | 1993 | Genomics1993，17，： | 1 |
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