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1篇 您的检索式:作者名="Tomas Poskus"
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1Gastrectomy impact on the gut microbiome in patients with gastric cancer:A comprehensive review显示文摘Gastric cancer is one of the most common malignancies worldwide and gastrectomy remains the only potentially curative treatment option for this disease.However,the surgery leads to significant physiological and anatomical changes in the gastrointestinal(GI)tract including loss of the gastric barrier,an increase in oxygenation levels in the distal gut,and biliary diversion after gastrectomy.These changes in the GI tract influence the composition of the gut microbiome and thus,host health.Gastrectomy-induced dysbiosis is characterized by increased abundance of typical oral cavity bacteria,an increase in aero-tolerant bacteria(aerobes/facultative anaerobes),and increased abundance of bile acidtransforming bacteria.Furthermore,this dysbiosis is linked to intestinal inflammation,small intestinal bacterial overgrowth,various GI symptoms,and an increased risk of colorectal cancer.Vaidota Maksimaityte Augustinas Bausys Marius Kryzauskas Martynas Luksta Ieva Stundiene Klaudija Bickaite Bernardas Bausys Tomas Poskus Rimantas Bausys Kestutis Strupas 2021World Journal of Gastrointestinal Surgery2021,13,7:0
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