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| 1 | Computed tomography perfusion imaging as a potential imaging biomarker of colorectal cancer显示文摘Neovascularization was reported to arise early in the adenoma-carcinoma sequence in colorectal cancer(CRC),and the importance of angiogenesis in cancer progression has been established.Computed tomography(CT)perfusion(CTP)based on high temporal resolution CT images enables evaluation of hemodynamics of tissue in vivo by modeling tracer kinetics.CTP has been reported to characterize tumor angiogenesis,and to be a sensitive marker for predicting recurrence or survival in CRC.In this review,we will discuss the biomarker value of CTP in the management of CRC patients. | Koichi Hayano Takeshi Fujishiro Dushyant V Sahani Asami Satoh Tomoyoshi Aoyagi Gaku Ohira Toru Tochigi Hisahiro Matsubara Kiyohiko Shuto | 2014 | World Journal of Gastroenterology2014，20，46： | 5 |
| 2 | 吡柔比星膀胱灌注预防非肌层浸润性膀胱癌术后复发显示文摘本文回顾性评价了非肌层浸润性膀胱癌患者TURBT术后3d连续膀胱灌注吡柔比星(THP)的疗效。1995年3月至2009年4月总计184例非肌层浸润性膀胱癌患者TURBT术后3d连续灌注THP(将30mgTHP溶解于40ml无菌注射用水中灌注)。 | Tochigi T | 2015 | 现代泌尿生殖肿瘤杂志2015，7，4： | 2 |
| 3 | 为与窒息肠塞痛联系的肠的局部缺血的察觉的动态 CT 的动脉的阶段的用途显示文摘 AIM:To clarify the usefulness of arterial phase scans in contrast computed tomography (CT) imaging of stran-gulation ileus in order to make an early diagnosis. METHODS:A comparative examination was carried out with respect to the CT value of the intestinal tract wall in each scanning phase, the CT value of the content in the intestinal tract, and the CT value of ascites fluid in the portal vein phase for a group in which ischemia was observed (Group Ⅰ) and a group in which ischemia was not observed (Group N) based on the pathological findings or intra-surgical findings. Moreover, a comparative examination was carried out in Group Ⅰ subjects for each scanning phase with respect to average differences in the CT values of the intestinal tract wall where ischemia was suspected and in the intestinal tract wall in non-ischemic areas. RESULTS:There were 15 subjects in Group Ⅰ and 30 subjects in Group N. The CT value of the intestinal tract wall was 41.8 ± 11.2 Hounsfield Unit (HU) in Group Ⅰ and 69.6 ± 18.4 HU in Group N in the arterial phase, with the CT value of the ischemic bowel wall being significantly lower in Group Ⅰ. In the portal vein phase, the CT value of the ischemic bowel wall was 60.6 ± 14.6 HU in Group Ⅰ and 80.7 ± 17.7 HU in Group N, with the CT value of the ischemic bowel wall being significantly lower in Group Ⅰ; however, no significant differences were observed in the equilibrium phase. The CT value of the solution in the intestine was 18.6 ± 9.5 HU in Group Ⅰ and 10.4 ± 5.1 HU in Group N, being signifi-cantly higher in Group Ⅰ. No significant differences were observed in the CT value of the accumulation of ascites fluid. The average difference in the CT values between the ischemic bowel wall and the non-ischemic bowel wall for each subject in Group Ⅰ was 33.7 ± 20.1 HU in the arterial phase, being significantly larger compared to the other two phases. CONCLUSION:This is a retrospective study using a small number of subjects; however, it suggests that there is a possibility that CT scanning in the arterial phase is useful for the early diagnosis of strangulation ileus. | Gaku Ohira Kiyohiko Shuto Tsuguaki Kono Takayuki Tohma Hisashi Gunji Kazuo Narushima Shunsuke Imanishi Takeshi Fujishiro Tohru Tochigi Toshiharu Hanaoka Hideaki Miyauchi Naoyuki Hanari Hisahiro Matsubara Noriyuki Yanagawa | 2012 | World Journal of Radiology2012，4，11： | 2 |
| 4 | Imaging biomarkers for the treatment of esophageal cancer显示文摘Esophageal cancer is known as one of the malignant cancers with poor prognosis.To improve the outcome,combined multimodality treatment is attempted.On the other hand,advances in genomics and other“omic”technologies are paving way to the patient-oriented treatment called“personalized”or“precision”medicine.Recent advancements of imaging techniques such as functional imaging make it possible to use imaging features as biomarker for diagnosis,treatment response,and prognosis in cancer treatment.In this review,we will discuss how we can use imaging derived tumor features as biomarker for the treatment of esophageal cancer. | Koichi Hayano Gaku Ohira Atsushi Hirata Tomoyoshi Aoyagi Shunsuke Imanishi Toru Tochigi Toshiharu Hanaoka Kiyohiko Shuto Hisahiro Matsubara | 2019 | World Journal of Gastroenterology2019，25，24： | 2 |
| 5 | Mass screening for prostate cancer: a comparative study in Natori, Japan and Changchun(China)显示文摘 | Kuwahara M Tochigi T Kawamura S | 2003 | Urology2003，61，1： | 1 |
| 6 | Differential effects of urinary and recombinant chorionic gonadotropin on oxida- tive stress responses in deeidualizing human endometrial stromal cells显示文摘 | KAJIHARA T TOCHIGI H UCHINO S | 2011 | Placenta2011，32，8： | 1 |
| 7 | Sensitive and convenient yeast reporter assay for high - throughput analysis by using a secretory luciferase from Cypridina noctiluca 显示文摘 | Tochigi Y Sato N Sahara T | 2010 | Anal Chem2010，82，13： | 1 |
| 8 | The intravesical recurrence after 3 - day consecutive intravesical instillation of pirarubicine hydrochloride ( THP ) following transurethral resection of bladder tumor( TUR - BT) for non - muscle - invasive bladder cancer显示文摘 | Tochigi T Sakurada Y Aoki H | 2012 | Nihon Hinyokika Gakkai Zasshi2012，103，4： | 1 |
| 9 | Fresh osteochondral all- ografting for osteoehondral lesions of the talus 显示文摘 | Anderson DD Tochigi Y Rudert M J | 2010 | Foot Ankle Int2010，31，4： | 1 |
| 10 | Association study between the TNXB locus and schizophrenia in a Japanese population 显示文摘 | Tochigi M Zhang X Ohashi J | 2007 | Am J Med Genet B Neuropsyehiatr Genet2007，144，3： | 1 |
| 11 | Mass screening for prostate cancer: a comparative study in Natori, Japan and Changchun, China显示文摘 | Kuwahara M Tochigi T Kawamura S | 2003 | Urology2003，61，1： | 1 |
| 12 | Inhaled hydrogen gas therapy for prevention of lung transplant-induced ischemi- a/reperfusion injury in rats显示文摘 | Kawamura T Huang C S Tochigi N | 2010 | Transplantation2010，90，12： | 1 |
| 13 | Distribution and progression of chondrocyte damage in a whole-organ model of human ankle intra-articular fracture显示文摘 | Tochigi Y Buckwalter JA Martin JA | 2011 | J Bone Joint Surg Am2011，93，6： | 1 |
| 14 | MTBP plays a crucial role in mitotic progression and chromosome segregation显示文摘 | Agarwal N Tochigi Y Adhikari AS | 2011 | Cell Death Differ2011，18，7： | 1 |
| 15 | Hydrogen peroxideinduces cell death in human TRAIL-resistant melanoma throughintracellular superoxide generation 显示文摘 | Tochigi M Inoue T Suzuki-Karasaki M | 2013 | Int J Oncol2013，42，3： | 1 |
| 16 | Influence of the interosseous talocalcaneal ligament injury on stability of the ankle-subtalar joint com- plex: a cadaveric experimental study 显示文摘 | Tochigi Y Takabashi K Yamagata M | 2002 | Foot Ankle Int2002，23，： | 1 |
| 17 | Comparison between the location and the histomorphological/immunohistochemical characteristics of noninvasive neoplasms of the ampulla of Vater显示文摘 | Yoshiro Yamamoto Tetsuo Nemoto Yoichiro Okubo Yasuhiro Nihonyanagi Takao Ishiwatari Kensuke Takuma Naobumi Tochigi Naoki Okano Megumi Wakayama Yoshinori Igarashi Kazutoshi Shibuya | 2014 | Human Pathology2014，，9： | 1 |
| 18 | Thoracic discectomy by posterior pedicle-sparing,transfacet approach with real-time intraoperative ultrasonography:Clinical article显示文摘 | Nishimura Y Thani NB Tochigi S | 2014 | J Neurosurg Spine2014，21，4： | 1 |
| 19 | Prediction of non-polar gas solubilities in water, alcohols and aqueous alcohol solutions by the modified ASOG method 显示文摘 | Tochigi K Kojima K | 1982 | Fluid Phase Equilibria1982，8，： | 1 |
| 20 | Tissue platinum concentration following preoperative balder occluded arterial infusion (BOAI) for bladder cancer显示文摘 | Tochigi H Hayashi N Hoskin A | 1995 | J Jpn Soc Cancer Ther1995，30，2： | 1 |
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