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16篇 您的检索式:作者名="Tison T"
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1De novo malignancies after liver transplantation: The effect of immunosuppression-personal data and review of literature显示文摘BACKGROUND Immunosuppression has undoubtedly raised the overall positive outcomes in the post-operative management of solid organ transplantation. However, long-term exposure to immunosuppression is associated with critical systemic morbidities. De novo malignancies following orthotopic liver transplants (OLTs) are a serious threat in pediatric and adult transplant individuals. Data from different experiences were reported and compared to assess the connection between immunosuppression and de novo malignancies in liver transplant patients. AIM To study the role of immunosuppression on the incidence of de novo malignancies in liver transplant recipients. METHODS A systematic literature examination about de novo malignancies and immunosuppression weaning in adult and pediatric OLT recipients was described in the present review. Worldwide data were collected from highly qualified institutions performing OLTs. Patient follow-up, immunosuppression discontinuation and incidence of de novo malignancies were reported. Likewise, the review assesses the differences in adult and pediatric recipients by describing the adopted immunosuppression regimens and the different type of diagnosed solid and blood malignancy.RESULTS Emerging evidence suggests that the liver is an immunologically privileged organ able to support immunosuppression discontinuation in carefully selected recipients. Malignancies are often detected in liver transplant patients undergoing daily immunosuppression regimens. Post-transplant lymphoproliferative diseases and skin tumors are the most detected de novo malignancies in the pediatric and adult OLT population, respectively. To date, immunosuppression withdrawal has been achieved in up to 40% and 60% of well-selected adult and pediatric recipients, respectively. In both populations, a clear benefit of immunosuppression weaning protocols on de novo malignancies is difficult to ascertain because data have not been specified in most of the clinical experiences. CONCLUSION The selected populations of tolerant pediatric and adult liver transplant recipients greatly benefit from immunosuppression weaning. There is still no strong clinical evidence on the usefulness of immunosuppression withdrawal in OLT recipients on malignancies. An interesting focus is represented by the complete reconstitution of the immunological pathways that could help in decreasing the incidence of de novo malignancies and may also help in treating liver transplant patients suffering from cancer.Tommaso Maria Manzia Roberta Angelico Carlo Gazia Ilaria Lenci Martina Milana Oludamilola T Ademoyero Domiziana Pedini Luca Toti Marco Spada Giuseppe Tisone Leonardo Baiocchi 2019World Journal of Gastroenterology2019,25,35:3
2Fuzzy Behavior of Mechanical Systems with Uncertain Boundary Condi- tions 显示文摘Cherki A Plessis G Lallemand B Tison T Level P 2000Computer Methods in Applied Mechanics and Engineering2000,189,:1
3Marginal donors in liver transplantation显示文摘Tisone G Manzia T M Zazza S 2004Transplant Proc2004,36,3:1
4FuzzyBehavior of Mechanical Systems with Uncertain Boundary Condi-tions显示文摘A Cherki G Plessis B Lallemand T Tison and P Level 2000Computer Methods in Applied Mechanics and Engineer-ing2000,189,3:1
5The Italian Registry of Pediatric Therapeutic Apheresis: a report on activity during 2005 显示文摘De Silvestro G Tison T Vicarioto M 2009J Clin Apher2009,24,1:1
6Kinetic spray coatings显示文摘VAN STEENKISTE T H SMITH J R TEETS R E MOLESKI J J GORKIEWICZ D W TISON R P MARANTZ D R KOWALSKY K A RIGGS W L ZAJCHOWSKI P H PILSNER B MCCUNE R C BARNETT K J 1999Surf Coat Technol1999,111,1:1
7Fuzzy model finite element analysis of structures with imprecise material properties显示文摘LALLEMENT B CHERKI A TISON T 2000Journal of Sound and Vibration2000,220,:1
8Fuzzy multiobjective optimi- zation of mechanical structures 显示文摘Massa F Lallemand B Tison T 2009Computer Methods in Applied Mechanics and Engineering2009,198,58:1
9The italian registry of pediatric therapeutic apheresis:a report on activity during 2005显示文摘de SILVESTRO G TISON T VICARIOTO M 2009J Clin Apher2009,24,1:1
10Fuzzy modal analysis: prediction of experimental behaviours 显示文摘Massa F Tison T Lallemand B 2009Journal of Sound and Vibration2009,322,:1
11Neumann expansion for fuzzy finite element analysis显示文摘 Plessis G Tison T 1999Engineering Computations1999,16,:1
12Kinetic spray coatings显示文摘van STEENKISTE T H SMITH J R TEETS R E MOLESKI J J GORKIEWICZ D W TISON R P MARANTZ D R KOWALSKY K A RIGGS W L ZAJCHOWSKI P H 1999Surface and Coatings Technology1999,111,1:1
13Fuzzy modal analysis: prediction of experimental behaviors显示文摘Massa F Tison T Lallemand B 2009Journal of Sound and Vibration2009,322,:1
14Improvement in the predictivity of squeal simulations: Uncertainty and robustness显示文摘TISON T HEUSSAFF A MASSA F 2014Journal of Sound and Vibration2014,333,15:1
15Kinetic and Mechanism of Platium Silicide Formation on Silicon显示文摘Poate J M Tisone T C 1974Appl Phys Lett1974,24,8:1
16显示文摘Sun R C Tisone T C Cruzan P O 1973J Appl Phys1973,44,3:1
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