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| 1 | 日粮中添加CLA混合物对山羊生产性能、免疫反应及脂肪酸成分的影响显示文摘试验选取41日龄49头断奶山羊(体重15kg±2.9kg,)用于评价育肥期山羊日粮中添加CLA混合物对肉中脂肪酸成分、体液免疫反应的影响。山羊分为6个圈饲养并按以下处理分为3组:对照组(CT),精料中不添加CLA混合物;试验1组,精料中添加2.5g/kg CLA混合物(c-9,t-11CLA和t-10,c-12CLA以50∶50比例混合)(low-CLA);试验2组,精料中添加10g/kg CLA混合物(high-CLA)。动物自由采食直到屠宰期(25kg±1.6kg)。每周称重控制屠宰前动物的体重,断奶后1周(48d±16.9d)所有动物通过皮下注射2mg卵清蛋白。注射前及接种14d后采集血液分析体液免疫效果。动物右侧背最长肌采自每个处理的5头母畜。所有动物的屠宰体重、肉重无显著差异,抗体对卵清蛋白的反应差异不显著。各处理组间肌肉的脂肪成分也无显著差异。然而high-CLA组的c-9,t-11CLA和t-10,c-12CLA的含量高于low-CLA组和对照组(c-9,t-11CLA的含量为0.39、0.30和0.26g/100g FAME,t-10,c-12CLA的含量为0.051、0.013和0.014g/100g FAME)。总之,添加CLA不会影响体液的免疫,但通过增加c-9,t-11CLA和t-10,c-12CLA含量肉的脂肪酸成分会发生改变。 | Terré M 姜雅慧 | 2011 | 中国畜牧兽医2011，38，8： | 0 |
| 2 | Botulinum toxin treatment for oropharyngeal dysphagia in patients with stroke显示文摘 | R. Terré A. Panadés F. Mearin | 2013 | Neurogastroenterol. Motil2013，，： | 1 |
| 3 | Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701):a randomised,open-label,phase 3 study显示文摘 | Castaigne S Pautas C Terré C | 2012 | Lancet2012，379，9825： | 1 |
| 4 | Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701):a randomised,open-label,phase 3 study显示文摘 | Castaigne S Pautas C Terré C | 2012 | Lancet2012，379，9825： | 1 |
| 5 | What do preweaned and weaned calves need in the diet:A high fiber content or a forage source显示文摘 | TerréM Pedrals E Dalmau A | 2013 | Journal of Dairy Science2013，96，8： | 1 |
| 6 | Detection of hepatic metastases:Ferumoxides-enhanced MR imaging versus unenhanced MR imaging and CT during arterial portography显示文摘 | Senéterre E Taourel P Bouvier Y | 1996 | Radiology1996，200，3： | 1 |
| 7 | Treatment of oropharyngeal dysphagia with neuromuscular electrostimulation显示文摘 | Terré R Martinell M Gonzá1ez B | 2013 | Med Clin2013，140，4： | 1 |
| 8 | 不同来源饲草对荷斯坦犊牛生产性能和饲养行为的影响显示文摘采用公荷斯坦犊牛(44.7 kg、8.3 d)179头进行3个系列试验,旨在评估不同饲草来源对犊牛生产性能、表观消化率和饲养行为的影响。在每个试验中,犊牛随机分配给3个不同的日粮处理:对照组(CON组)犊牛饲喂开食料,不提供饲草(3个试验对照组相同),其他两个处理由同样的开食料和饲草组成:第1个试验,铡碎苜蓿(AH组)和黑麦草干草(RH组);第2个试验,铡碎燕麦草(OH组)和铡碎大麦秸(BS);第3个试验,玉米青贮(CS组)和黑小麦(TS组)。所有犊牛通过饲喂12.5%干物质代乳品2 L直到50日龄;断奶前(57日龄)1周,饲喂12.5%干物质代乳品2 L。试验至犊牛71日龄。每天记录开食料、代乳品和饲草采食量,每周测定犊牛的体重。犊牛单独关养,用木屑作垫料。结果表明,与对照组相比,获得OH、TS和BS的犊牛采食较多的开食料(分别为0.88,1.14、1.17、1.06 kg.d-1)和较高的平均日增重(分别为0.72,0.93、0.88、0.88 kg.d-1)。RH、BS、CS和TS组犊牛比AH组犊牛(120 g.d-1)和OH组犊牛(101 g.d-1)采食较少的饲草(51 g.d-1)。处理之间的有机物、干物质和中性洗涤纤维表观消化率无显著差异(分别为81.5、81.1和54.4%)。RH组、CS组和AH组的粗蛋白表观消化率比CON组大(分别为80.5、76.4%)。饲喂代乳品和固体饲料1 h后,与CON组犊牛相比,AH组犊牛采食开食料和躺卧时间较少,AH组和RH组犊牛反刍时间较长,比值分别为5.24和5.40。AH组和RH组犊牛作出非营养性口唇行为的时间较少(OR分别为0.38和0.34),TS组犊牛作出非营养性行为的时间趋于较少(OR为0.21)。结果表明,犊牛自由选择饲草来源可改善其采食量和生产性能,而不会影响干物质、有机物、粗蛋白质、中性洗涤纤维的消化率,并且依据饲草来源,减少非营养性口唇行为,促进反刍。 | Castells L L Bach A Araujo G Montoro C Terré M 张树金 | 2012 | 饲料博览2012，，3： | 0 |
| 9 | Use of chitosan-based edible coatings in combination with other natural compounds, to control Rhizopus stolonifer and Escherichia coli DH5α in fresh tomatoes显示文摘 | Margarita Ramos-García Elsa Bosquez-Molina Jesús Hernández-Romano Guadalupe Zavala-Padilla Eduardo Terrés-Rojas Irán Alia-Tejacal Laura Barrera-Necha Mónica Hernández-López Silvia Bautista-Ba?os | 2012 | Crop Protection2012，，： | 1 |
| 10 | Efficient anchorage of Pt clusters on N-doped carbon nanotubes and their catalytic activity显示文摘 | Xavier Lepró Eduardo Terrés Yadira Vega-Cantú Fernando J. Rodríguez-Macías Hiroyuki Muramatsu Yoon Ahm Kim Takuya Hayahsi Morinobu Endo Miguel Torres R. Mauricio Terrones | 2008 | Chemical Physics Letters2008，，： | 1 |
| 11 | CD300a inhibits CD16-mediated NK cell effector functions in HIV-1-infected patients显示文摘Natural killer(NK)cell-mediated antibody-dependent cellular cytotoxicity(ADCC)through CD16 plays a critical role in antihuman immunodeficiency virus(HIV)responses.1–3 CD300a is a surface receptor highly expressed on NK cells that has the capacity to inhibit NK cell-mediated cytotoxicity in healthy donors.4 The CD300a molecule has been related to several viral infections and is able to diminish the NK cell killing of pseudorabies-infected cells through interactions with its ligands phosphatidylserine and phosphatidylethanolamine.5 In addition,CD300a expression on B and CD4+T lymphocytes is altered during HIV-1 infection,and combined antiretroviral therapy(cART)does not restore nonpathological expression levels.5,6 However,the expression and function of CD300a on NK cells during HIV-1 infection is still unknown.We have determined the surface expression of CD300a on different NK cell subsets and the capacity of this receptor to inhibit CD16-induced NK cell effector functions in healthy and HIV-1 infected individuals. | Joana Vitallé Iñigo Terrén Ane Orrantia Raquel Pérez-Garay Francesc Vidal JoséA.Iribarren Carmen Rodríguez Ana M.López Lirola Enrique Bernal Olatz Zenarruzabeitia Francisco Borrego | 2019 | Cellular & Molecular Immunology2019，16，12： | 0 |
| 12 | Intertwined leukocyte balances in tumours and peripheral blood as robust predictors of right and left colorectal cancer survival显示文摘BACKGROUND Colorectal cancer(CRC)accounts for 9.4%of overall cancer deaths,ranking second after lung cancer.Despite the large number of factors tested to predict their outcome,most patients with similar variables show big differences in survival.Moreover,right-sided CRC(RCRC)and left-sided CRC(LCRC)patients exhibit large differences in outcome after surgical intervention as assessed by preoperative blood leukocyte status.We hypothesised that stronger indexes than circulating(blood)leukocyte ratios to predict RCRC and LCRC patient outcomes will result from combining both circulating and infiltrated(tumour/peritumour fixed tissues)concentrations of leukocytes.AIM To seek variables involving leukocyte balances in peripheral blood and tumour tissues and to predict the outcome of CRC patients.METHODS Sixty-five patients diagnosed with colon adenocarcinoma by the Digestive Surgery Service of the La Paz University Hospital(Madrid,Spain)were enrolled in this study:43 with RCRC and 22 with LCRC.Patients were followed-up from January 2017 to March 2021 to record overall survival(OS)and recurrence-free survival(RFS)after surgical interventions.Leukocyte concentrations in peripheral blood were determined by routine laboratory protocols.Paraffin-fixed samples of tumour and peritumoural tissues were assessed for leukocyte concentrations by immunohistochemical detection of CD4,CD8,and CD14 marker expression.Ratios of leukocyte concentration in blood and tissues were calculated and evaluated for their predictor values for OS and RFS with Spearman correlations and Cox univariate and multivariate proportional hazards regression,followed by the calculation of the receiver-operating characteristic and area under the curve(AUC)and the determination of Youden’s optimal cutoff values for those variables that significantly correlated with either RCRC or LCRC patient outcomes.RCRC patients from the cohort were randomly assigned to modelling and validation sets,and clinician-friendly nomograms were developed to predict OS and RFS from the respective significant indexes.The accuracy of the model was evaluated using calibration and validation plots.RESULTS The relationship of leukocyte ratios in blood and peritumour resulted in six robust predictors of worse OS in RCRC:CD8+lymphocyte content in peritumour(CD8pt,AUC=0.585,cutoff<8.250,P=0.0077);total lymphocyte content in peritumour(CD4CD8pt,AUC=0.550,cutoff<10.160,P=0.0188);lymphocyte-to-monocyte ratio in peritumour(LMRpt,AUC=0.807,cutoff<3.185,P=0.0028);CD8+LMR in peritumour(CD8MRpt,AUC=0.757,cutoff<1.650,P=0.0007);the ratio of blood LMR to LMR in peritumour(LMRb/LMRpt,AUC=0.672,cutoff>0.985,P=0.0244);and the ratio of blood LMR to CD8+LMR in peritumour(LMRb/CD8MRpt,AUC=0.601,cutoff>1.485,P=0.0101).In addition,three robust predictors of worse RFS in RCRC were found:LMRpt(AUC=0.737,cutoff<3.185,P=0.0046);LMRb/LMRpt(AUC=0.678,cutoff>0.985,P=0.0155)and LMRb/CD8MRpt(AUC=0.615,cutoff>1.485,P=0.0141).Furthermore,the ratio of blood LMR to CD4+LMR in peritumour(LMRb/CD4MRpt,AUC=0.786,cutoff>10.570,P=0.0416)was found to robustly predict poorer OS in LCRC patients.The nomograms showed moderate accuracy in predicting OS and RFS in RCRC patients,with concordance index of 0.600 and 0.605,respectively.CONCLUSION Easily obtainable variables at preoperative consultation,defining the status of leukocyte balances between peripheral blood and peritumoural tissues,are robust predictors for OS and RFS of both RCRC and LCRC patients. | Ramón Cantero-Cid Karla Marina Montalbán-Hernández Jenny Guevara Alejandro Pascual-Iglesias Elisa Pulido JoséCarlos Casalvilla Cristóbal Marcano Cristina Barragán Serrano Jaime Valentín Gloria Cristina Bonel-Pérez JoséAvendaño-Ortiz Verónica Terrón Roberto Lozano-Rodríguez Alejandro Martín-Quirós Elvira Marín Eva Pena Laura Guerra-Pastrián Eduardo López-Collazo Luis Augusto Aguirre | 2022 | World Journal of Gastrointestinal Oncology2022，14，1： | 1 |
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