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| 1 | Irritable bowel syndrome symptom severity improves equally with probiotic and placebo显示文摘AIM To determine the effects of Lactobacillus acidophilus NCFM on irritable bowel syndrome(IBS) symptoms and quality of life(Qo L).METHODS In this randomized triple-blind trial, adult IBS volunteerswho were recruited according to Rome Ⅲ criteria received 109 or 1010 colony-forming units of NCFM or placebo daily for 12 wk. IBS Symptom Severity Score(IBS-SSS), which constituted the primary outcome, and secondary outcomes, including individual IBS symptoms, IBS-related QoL questionnaire, anxiety and depression, defecation frequency, and stool consistency, were assessed at baseline at the end of the 8-wk runin period, after 4 and 12 wk of intervention, and after a 4-wk washout.RESULTS A total of 340 of 391 randomized volunteers completed the trial. IBS-SSS improved over 12 wk of treatment in all treatment groups, decreasing by a mean ± SD of 44.0 ± 80.2, 50.8 ± 82.4, and 48.3 ± 72.2 in the placebo, active low-dose, and active high-dose groups, respectively. Similarly, secondary outcomes did not differ between treatment groups. However, in a post hoc analysis of volunteers with moderate to severe abdominal pain at baseline(VAS > 35/100), the treatment significantly reduced the sensation of abdominal pain. Pain scores fell by 20.8 ± 22.8, 29.4 ± 17.9, and 31.2 ± 21.9 in the placebo, active low-dose, and active high-dose groups, respectively(P value for placebo vs combined active doses = 0.0460).CONCLUSION NCFM alleviates moderate to severe abdominal pain, consistent with earlier observations of this strain mitigating visceral pain through increased analgesic receptor expression. | Anna Lyra Markku Hillila Teppo Huttunen Sofia Mannikko Mikko Taalikka Julia Tennila Anneli Tarpila Sampo Lahtinen Arthur C Ouwehand Lea Veijola | 2016 | World Journal of Gastroenterology2016，22，48： | 7 |
| 2 | 热电厂烟气余热回收用于集中供热的系统形式及参数分析显示文摘目前我国燃煤热电厂在能源供应中的比例占到了40%以上,却很少回收大量烟气余热,尤其以供热为目标的余热回收项目更加少见,造成了严重的环境污染和能源浪费.文中对基于直接接触式换热和吸收式热泵技术的烟气余热梯级回收利用系统建立相应的数学模型,提出一种烟气余热回收用于集中供热的方案,探究影响该系统初投资的主要参数,分析了热网回水温度对系统能效的影响及排烟温度对系统供热能力的影响.计算分析表明,当烟气入口温度为80℃时,板式换热器的冷端温差Δt_(c)从5℃降低至2℃,单位回收余热量投资费用P降低13%,表明降低Δt_(c)可降低该系统的初投资;排除外界干扰,在热电工况相同的情况下,随着回水温度由36℃降低到25℃供热等效电W由55.6 kWh/GJ降至50.6 kWh/GJ,系统的能效得到提高;当排烟温度从50℃降低至20℃,系统余热回收能力提高80%. | 王海超 刘哲毅 李骥 Esa Teppo Katja Granlund Illka Haavisto 余力 | 2021 | 东北电力大学学报2021，41，2： | 3 |
| 3 | Growth of Chlamydia pneumoniae in cultured human peripheral blood mononuclear cells and induction of acytokine response显示文摘 | Kaukoranta-Tolvanen SS Teppo AM Laitinen K | 1996 | Microb Pathog1996，21，： | 1 |
| 4 | Multiple cancer-an epidemiologic exercise in Finland 显示文摘 | Teppo L Pukkala E Saxen E | 1985 | J Natl Cancer Inst1985，75，： | 1 |
| 5 | Pleural fluid interferon-γ and tumour necrosis factor-α in tuberculous and rheumatoid pleurisy显示文摘 | Soderblom T Nyberg P Teppo A M | 1996 | Eur Respir J1996，9，8： | 1 |
| 6 | Diabetic nephropathy is associated with low-grade inflammation in type I diabetic pationts显示文摘 | Saraheimo M Teppo AM Forsblom C | 2003 | Diabetologia Med2003，46，20： | 1 |
| 7 | Adhesion molecules and urinary tumor necrosis factor-alpha in idiopathic membranous glomerulonephritis显示文摘 | Honkanen E Von-Willebrand Teppo M | 1998 | Kidney Int1998，53，4： | 1 |
| 8 | Diabetic nephmpathy is associated with low-grade inflammation in Type 1 diabetic patients显示文摘 | Saraheimo M Teppo AM Forsblom C | 2003 | Diabetologia2003，46，10： | 1 |
| 9 | Diet and breast cancer risk in a cohort of Finnish women 显示文摘 | Jarvinen R Knekt P Seppanen R Teppo L | 1997 | Cancer Letters1997，114，12： | 1 |
| 10 | Lower urinary- interleukin-1 receptor-antagonist excretion in IgA nephropathy than in Henoch-Sch?nlein nephritis显示文摘 | Rauta V Teppo AM T?mroth T | 2003 | Nephrol Dial Transplant2003，18，9： | 1 |
| 11 | Design and analysis of a scaled model of a high-rise,high-speed elevator显示文摘 | Zhua W D Teppo L J | | 0，，： | 1 |
| 12 | Soluble Fas and Fas ligand in human tear fluid after photorefractive keratectomy显示文摘 | Tuominen I Vesaluoma M Teppo A M | | 0，，12： | 1 |
| 13 | Organizational Economics of Capability and Heterogeneity显示文摘 | Nicholas S. Argyres Teppo Felin Nicolai Foss Todd Zenger | 2012 | Organization Science2012，，5： | 1 |
| 14 | Plasma IL-6 concentration is inversely related to insulin sensitivity,and acute-phase proteins associate with glucose and lipid metabolism in healthy subjects显示文摘 | Heliovaara MK Teppo AM Karonen SL | 2005 | Diabetes Obes Metab2005，7，6： | 1 |
| 15 | Prognostic factors in laryngeal carcinoma: the role of apoptosis, p53, prolifer- ation ( Ki-67 ) and angiogenesis 显示文摘 | Teppo H Soini Y Melkko J | 2003 | APMIS2003，111，： | 1 |
| 16 | Acute phase proteins during hemodialysis:correlations with serum interleukin-1 beta levels and different dialysis membranes显示文摘 | Honkanen E Gronhagen-Riska C Teppo AM | 1991 | Nephron1991，57，3： | 1 |
| 17 | Release of TGF-beta 1 and VEGF in tears following photorefractive keratectomy显示文摘 | Vesaluoma M Teppo A M Gronhagen-Riska C | | 0，，01： | 1 |
| 18 | Decreased urinary eseretion of vascular endothelial growth factor in idiopathic membranous glomerulonephritis 显示文摘 | Honkanen EO Teppo AM Gronhagen-Riska C | 2000 | Kidney Int2000，57，6： | 1 |
| 19 | Plasma IL-6 concentration is inversely related to imsulin sensitivity, and acute-phase proteins associate with glucose and lipid metabolism in heahhy subjects 显示文摘 | Heliovaara MK Teppo AM Karonen SL | 2005 | Diab Obes Metab2005，7，6： | 1 |
| 20 | The hypoxic tumor microen- vimnment regulates invasion of aggressive oral carcinoma cells 显示文摘 | Teppo S Sundquist E Vered M | 2013 | Exp Cell Res2013，319，4： | 1 |
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