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330篇 您的检索式:作者名="Tan AS"
    题名 作者 年代 出处 被引量
1Construction and characterization of an experimental ISCOMS-based hepatitis B polypeptide vaccine显示文摘瞄准:描绘生物化学并且基于 HBsAg 的 T 房间 epitopes 从新奇治疗学的多肽准备的一支试验性的 ISCOMS 疫苗的免疫学的性质,和 heptatis B-ISCOMS 被准备并且调查。方法:刺激建筑群(ISCOMS ) 的免疫基于疫苗的包含新奇治疗学的肝炎 B 多肽被分离方法准备,并且它的形成被 SDS-polyacrylamide 胶化电气泳动化学上验证的电子显微镜学和简历设想。在 ISCOMS 以内的肽的数量被 Bradford 试金决定,并且特定的 CTL 反应被 ELISPOT 试金检测。结果:有大约 40nm 的一条直径的 submicroparticle 的典型像笼子的结构被电子显微镜学观察。从 Bradford 试金的结果证明肽加入的水平关于 0.33g .L (-1) 。在到分子的重量标记(3480kDa ) 的第六个乐队的 paralleled 位置结束,一个清楚的乐队在 SDS 页分析被给看,显示进 ISCOMS 的多肽的成功的加入。ISCOMS 交货系统能高效地改进多肽的 immunogenicity 并且由 ELISPOT 试金的结果在 vivo 得到特定的有免疫力的回答,这被建议,它证明生产房间(特定的 CTL 回答) 的 IFN-gamma 被增加(对待 ISCOMS 的组的点:47+/-5, n =3;控制组:5+/-2, n =3 ) 。结论:基于 ISCOMS 的肝炎 B 多肽疫苗成功地与在 vivo 疫苗的短多肽相比被构造,它导致更高的 CTL 回答。Xiao-Ju Guan Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 200031,China,previously worked as a postdoc in Institute of Immunology,Third Military Medical University,Chongqing 400038,China Xiao-Jun Guan,Department of Science & Research,Second Military Medical University,Shanghai 200433,China Yu-Zhang Wu Zheng-Cai Jia Tong-Dong Shi Yan Tan,Institute of Immunology,Third Military Medical University,Chongqing 400038,China 2002World Journal of Gastroenterology2002,8,2:11
2The 1982 revisedcriteria for the classification of systemic lupuserythematosus显示文摘Tan EM Cohen AS Fries JF 1982Arthritis Rheum1982,25,11:1
3The 1982 recised vriteria for the classification if systemic lupus erythematosus (SLE)显示文摘TAN EM COHEN AS FRIES JF 1982Arthritis Rheum1982,25,11:1
4The 1982 revised criteriafor the classification of systemic lupus erythematosus(SLE)显示文摘Tan EM Cohen AS Fries JF 1982Arthritis Rheum1982,25,:1
5The 1982 revised criteria for the classification of systemic lupus reythamtosus显示文摘Tan EM Cohen AS Freies JF 1982Arthritis Rheum1982,25,:1
6The 1982 revised criteria for the classfication of systemic lupus erythematosus 显示文摘Tan EM Cohen AS Fries JF 1982Arthritis Rheum1982,25,11:1
7The 1982 revised criteria for the classification of systemic lupus erythematosus显示文摘Tan EM Cohen AS Fries JF 1982Arthritis Rheum1982,25,11:1
8The 1982 revised criteria for the classification on systemic lupus erythermatosus(SLE) 显示文摘TAN EM Cohen AS Freis JF 1982Arthritis Rheum1982,25,:1
9The 1982 revised criteria for the classification of systemic lupus erythematosus 显示文摘Tan EM Cohen AS Fries JF 1982Arthritis Rheum1982,25,11:1
10The 1982 revised criteria for the classification of systemic lupus erythematosus显示文摘Tan EM Cohen AS Fries IF 1982Arthritis Rheum1982,25,11:1
11Inflammatory markers and the risk of Alzheimer disease: the Framingham Study 显示文摘Tan ZS Beiser AS Vasan RS 2007Neurolo- gy2007,68,22:1
12The 1982 revised criteria for the classification of systemic Lupus erythermatosus 显示文摘Tan EM Cohen AS Fries JF 1982Arthritis Rheum1982,25,11:1
13The 1982 revised criteria for the classification of systemic lupus erythematosus显示文摘Tan EM Cohen AS Fries JF 0,,11:1
14The 1982 revised criteria for the classification of systemic lupus erythematosus显示文摘Tan EM Cohen AS Fries JF 0,,11:1
15Abnormal expression of the p53 tumour suppressor gene in the conjunetiva of patients with pterygium显示文摘Tan DT Lim AS Goh HS 1997Am J Ophthalmol1997,123,:1
16Microsuture repair of in-tra-operative ruptures of cerebral aneurysms of the in-ternal carotid artery显示文摘Vashu R Tan S Wong AS 2009J Clin Neurosci2009,16,7:1
17Abnormal expression of the P53 tumor suppressor gene in the conjunctiva of patients with pterygiom 显示文摘Tan DT Lim AS Goh HS et at 1997Am J Ophthalmol1997,123,3:1
18The 1982 revised criteria for the classification of SLE显示文摘 Cohen AS Fries JF 1982Arthritis Rheum1982,25,:1
19The 1982 revised criteria for the classification of systemic lupus erythematosus 显示文摘 Cohen AS Fries JF 1982Arthritis Rheum1982,25,11:1
20Rapid one-day fluorescence in situ hybridisa- tion in prenatal diagnosis using uncultured amniocytes and chorion- icvilli显示文摘Cai LS Lim AS Tan A 1999Ann Acad Med Singapore1999,28,4:1
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