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4篇 您的检索式:作者名="Tambuwala M"
    题名 作者 年代 出处 被引量
1Three-dimensional bio-printing: A new frontier in oncology research显示文摘Current research in oncology deploys methods that rely principally on two-dimensional(2D) mono-cell cultures and animal models.Although these methodologies have led to significant advancement in the development of novel experimental therapeutic agents with promising anticancer activity in the laboratory, clinicians still struggle to manage cancer in the clinical setting.The disappointing translational success is attributable mainly to poor representation and recreation of the cancer microenvironment present in human neoplasia.Threedimensional(3D) bio-printed models could help to simulate this micro-environment, with recent bio-printing of live human cells demonstrating that effective in vitro replication is achievable.This literature review outlines up-to-date advancements and developments in the use of 3D bio-printed models currently being used in oncology research.These innovative advancements in 3D bio-printing open up a new frontier for oncology research and could herald an era of progressive clinical cancer therapeutics.Nitin Charbe Paul A McCarron Murtaza M Tambuwala 2017World Journal of Clinical Oncology2017,8,1:6
2An inact ca-nonical NF-kappaB pathway is required for inflammatory gene ex-pression in response to hypoxia显示文摘Fitzpatrick SF Tambuwala M Bruning U 2011J Imunol2011,186,2:1
3PGC - 1 alpha is coupled to HIF - 1 alpha - dependent gene expression by increasing mi- tochondrial oxygen consumption in skeletal muscle cells 显示文摘O' Hagan KA Cocchiglia S Zhdanov AV Tambuwala MM Cummins EP Monfared M 2009Proc Natl Acad Sci U S A2009,106,:1
4An intact canonical NF-κB pathway is required for inflammatory gene expression in response to hypoxia显示文摘FITZPATRICK S F TAMBUWALA M M 2011J Immunol2011,186,2:1
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