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| 1 | Effect of biofilm formation by clinical isolates of Helicobacter pylori on the efflux-mediated resistance to commonly used antibiotics显示文摘AIM To evaluate the role of biofilm formation on the resistance of Helicobacter pylori(H. pylori) to commonly prescribed antibiotics, the expression rates of resistance genes in biofilm-forming and planktonic cells were compared.METHODS A collection of 33 H. pylori isolates from children and adult patients with chronic infection were taken for the present study. The isolates were screened for biofilm formation ability, as well as for polymerase chain reaction(PCR) reaction with HP1165 and hp1165 efflux pump genes. Susceptibilities of the selected strains to antibiotic and differences between susceptibilities of planktonic and biofilm-forming cell populations were determined. Quantitative real-time PCR(qP CR) analysis was performed using 16 S r RNA gene as a H. pylori-specific primer, and two efflux pumps-specific primers, hp1165 and hefA.RESULTS The strains were resistant to amoxicillin, metronidazole, and erythromycin, except for one strain, but they were all susceptible to tetracycline. Minimum bactericidalconcentrations of antibiotics in the biofilm-forming cells were significantly higher than those of planktonic cells. qP CR demonstrated that the expression of efflux pump genes was significantly higher in the biofilm-forming cells as compared to the planktonic ones.CONCLUSION The present work demonstrated an association between H. pylori biofilm formation and decreased susceptibility to all the antibiotics tested. This decreased susceptibility to antibiotics was associated with enhanced functional activity of two efflux pumps: hp1165 and hefA. | Bahareh Attaran Tahereh Falsafi Nassim Ghorbanmehr | 2017 | World Journal of Gastroenterology2017，23，7： | 12 |
| 2 | Hepatitis B and liver transplantation: Molecular and clinical features that influence recurrence and outcome显示文摘Hepatitis B virus(HBV) continues to be a major cause of morbidity and mortality worldwide. It is estimated that about 350 million people throughout the world are chronically infected with HBV. Some of these people will develop hepatic cirrhosis with decompensation and/or hepatocellular carcinoma. For such patients, liver transplantation may be the only hope for cure or real improvement in quality and quantity of life. Formerly, due to rapidity of recurrence of HBV infection after liver transplantation, usually rapidly progressive, liver transplantation was considered to be contraindicated. This changed dramatically following the demonstration that hepatitis B immune globulin(HBIG), could prevent recurrent HBV infection. HBIG has been the standard of care for the past two decades or so. Recently, with the advent of highly active inhibitors of the ribose nucleic acid polymerase of HBV(entecavir, tenofovir), there has been growing evidence that HBIG needs to be given for shorter lengths of time; indeed, it may no longer be necessary at all. In this review, we describe genetic variants of HBV and past, present, and future prophylaxis of HBV infection during and after liver transplantation. We have reviewed the extant medical literature on the subject of infection with the HBV, placing particular emphasis upon the prevention and treatment of recurrent HBV during and after liver transplantation. For the review, we searched PubMed for all papers on the subject of 'hepatitis B virus AND liver transplantation'. We describe some of the more clinically relevant and important genetic variations in the HBV. We also describe current practices at our medical centers, provide a summary and analysis of comparative costs for alternative strategies for prevention of recurrent HBV, and pose important still unanswered questions that are in need of answers during the next decade or two. We conclude that it is now rational and cost-effective to decrease and, perhaps, cease altogether, the routine use of HBIG during and following liver transplantation for HBV infection. Here we propose an individualized prophylaxis regimen, based on an integrated approach and risk-assessment. | Tahereh Ghaziani Hossein Sendi Saeid Shahraz Philippe Zamor Herbert L Bonkovsky | 2014 | World Journal of Gastroenterology2014，20，39： | 7 |
| 3 | Activated Hard Shell of Apricot Stones: A Promising Adsorbent in Gold Recovery显示文摘活性炭被证明了是为从水溶液的许多金属离子的恢复的有效吸附物。在这研究,伊朗的李属石头的激活的难壳从 electro-plating 废水被用于金恢复。象吸附物的剂量和粒子大小那样的参数的效果,最适 PH,在金恢复上混合的焦虑速度被调查。结果证明在最佳操作条件下面,超过 98% 金离子在就 3 h 以后被吸附到活性炭上。另外,吸附的金牌能是从由剥去方法改进的这吸附物的 eluted。这个过程在缓冲冼脱与包含有机溶剂的水溶液跟随的环境温度与强碱包含黄金沉重的吸附物的接触。它被发现李属石头的那激活的难壳代替的潜力在黄金进口了商业活性炭吸附过程。 | Mansooreh Soleimani Tahereh Kaghazchi | 2008 | Chinese Journal of Chemical Engineering2008，16，1： | 6 |
| 4 | Application of Stool-PCR test for diagnosis of Helicobacter pylori infection in children显示文摘AIM:To evaluate the usefulness of stool-PCR test for diagnosis of Helicobacter pylori(H pylori)infection in pediatric populations. METHODS:Based on endoscopic features(including nodular gastritis,erosive duodenitis and ulcer)and/or a positive rapid urease test(RUT)obtained during endoscopy,28 children from a group of children admitted to the Children's Medical Center of Tehran for persistent upper gastrointestinal problems were selected to compare biopsy-based tests with stoolPCR.Their gastric activity and bacterial density were graded by the updated Sydney system,and their first stool after endoscopy was stored at-70℃.Biopsies were cultured on modified campy-blood agar plates and identified by gram-staining,biochemical tests,and PCR.Two methods of phenol-chloroform and boiling were used for DNA extraction from H pylori isolates. Isolation of DNA from stool was performed using a stool DNA extraction kit(Bioneer Inc,Korea).PCR was performed using primers for detection of vacA,cagA,and 16srRNA genes in both isolates and stool. RESULTS:Sixteen out of 28 child patients(57%) were classified as H pylori positive by biopsy-based tests,of which 11(39%)were also positive by stoolPCR.Sensitivity and specificity of stool-PCR was 62.5% and 92.3%respectively.H pylori was observed in histological sections for 10 out of 11 stool-positivepatients.Association was observed between higher score of H pylori in histology and positivity of stoolPCR.Also association was observed between the more severe form of gastritis and a positive stool-PCR. CONCLUSION:Association between higher score of H pylori in histology and a positive stool-PCR make it a very useful test for detection of H pylori active infection in children.We also suggest that a simple stool-PCR method can be a useful test for detection of H pylori virulence genes in stool. | Tahereh Falsafi Raha Favaedi Fatemeh Mahjoub Mehri Najafi | 2009 | World Journal of Gastroenterology2009，15，4： | 5 |
| 5 | Overexpression of Galectin-1 and Galectin-3 in hepatocellular carcinoma显示文摘Galectins(Gals)are evolutionarily conserved proteins that bind to b-galactoside containing glycans.Abnormal expression of Gals is associated with the development,progression,and metastasis of different types of cancer.Among the 11 Gals identified in humans,the roles of Gal-1 and Gal-3 have been extensively investigated in various tumors.Here,we summarize the roles of overly expressed Gal-1 and Gal-3 in the pathogenesis of hepatocellular carcinoma(HCC).The overexpression of Gal-1 and Gal-3 correlates with tumor growth,HCC cell migration and invasion,tumor aggressiveness,metastasis,and poor prognosis.A potentially promising future treatment strategy for HCC may include the combination of immunotherapy with Gal-1 inhibition.Additional research is warranted to investigate targeting Gal-1 and Gal-3 for HCC treatment. | Tahereh Setayesh Steven D.Colquhoun Yu-Jui Yvonne Wan | 2020 | Liver Research2020，4，4： | 5 |
| 6 | Effects of physical form of diet on nutrient digestibility, rumen fermentation, rumination,growth performance and protozoa population of finishing lambs显示文摘This study was conducted to compare effects of 3 physical forms of feed including mash(diet 1), pellet(diet 2) and complete feed block(CFB; diet 3) on digestion, fermentation and performance of lambs.Twenty-one lambs with an initial average body weight of 26 ± 2.5 kg and 6 ± 1.5 months of age were assigned through a completely randomized design to 3 treatments and 7 replicates. The experimental treatments had the same formulation. The results of present experiment showed that CFB significantly increased feed intake and nutrient digestibility(P < 0.05). There was no significant difference among the diets for rumen fluid pH, blood glucose, concentration of volatile fatty acids(P > 0.05), except acetic acid(P < 0.05). The rumen ammonia nitrogen(NH3-N), mixed rumen protozoa population(RPP), Entodiniums spp., Epidiniums spp., blood urea nitrogen(BUN) concentration, rumination time adjusted for dry matter(DM), neutral detergent fiber(NDF), acid detergent fiber(ADF) intake, and total body weight gain of lambs in CFB diet were the highest among all diets(P < 0.05). Feed conversion ratio at days 31 to 45 and whole experimental period were better in CFB than in other diets(P < 0.05). Overall, according to the findings of the present study, among 3 physical forms of the diets, CFB had the best efficiency due to improvement of nutrient digestibility, rumen fermentation and performance of lambs. Therefore, the CFB diet offers the best result in lambs compared with mash and pellet diets. | Elham Karimizadeh Morteza Chaji Tahereh Mohammadabadi | 2017 | Animal Nutrition2017，，2： | 5 |
| 7 | 氨基改性活性炭及其在水溶液中对铜的吸附特性(英文)显示文摘Activated carbons were prepared by two chemical methods and the adsorption of Cu(II) on activated carbons from aqueous solution containing amino groups was studied. The first method involved the chlorination of activated carbon following by substitution of chloride groups with amino groups, and the second involved the nitrilation of activated carbon with reduction of nitro groups to amino groups. Resultant activated carbons were characterized in terms of porous structure, elemental analysis, FTIR spectroscopy, XPS, Boehm titration,and p Hzpc. Kinetic and equilibrium tests were performed for copper adsorption in the batch mode. Also,adsorption mechanism and effect of p H on the adsorption of Cu(II) ions were discussed. Adsorption study shows enhanced adsorption for copper on the modified activated carbons, mainly by the presence of amino groups, and the Freundlich model is applicable for the activated carbons. It is suggested that binding of nitrogen atoms with Cu(II) ions is stronger than that with H+ions due to relatively higher divalent charge or stronger electrostatic force. | Mohammad Hassan Mahaninia Paria Rahimian Tahereh Kaghazchi | 2015 | Chinese Journal of Chemical Engineering2015，23，1： | 4 |
| 8 | Hepatitis B virus genotypes in southwest Iran: Molecular, serological and clinical outcomes显示文摘AIM: To investigate the associations of hepatitis B virus (HBV) genotype with HBeAg and anti-HBe status, alanine aminotransferase (ALT) levels and HBV-DNA detection in different groups of HBV-infected patients in southwest Iran. METHODS: A total of 89 HBsAg-positive serum samples were collected from the same number of patients. All sera were then investigated to determine HBV DNA and serological markers. For all the polymerase chain reaction (PCR)-positive samples, biochemical, histopathological assays and genotyping were also performed. RESULTS: Genotype D was the only type of HBV foundin different clinical forms of acute and chronic infections. There was a high prevalence of HBeAg-negative HBV- infected patients with chronic hepatitis (52.7%). Out of 55 patients with chronic hepatitis, seven (12.7%) were diagnosed with cirrhosis. A significant association between the presence of anti-HBe antibody and an increase in ALT level, among either HBeAg-negative (P = 0.01) or HBeAg-positive (P = 0.026) patients, was demonstrated. No significant differences were observed between the clinical outcomes of HBeAg-positive and -negative individuals (P = 0.24). CONCLUSION: Genotype D has been recognized as the only type of HBV found in different clinical forms of HBV infections, including cirrhosis, among the residents of southwest Iran. Anti-HBe possibly plays a role in disease progression in some patients with chronic hepatitis, at least for a period of disease. | Anahita Mojiri Abbas Behzad-Behbahani Mehdei Saberifirozi Maryam Ardabili Mahmood Beheshti Marjan Rahsaz Mehrdad Banihashemi Negar Azarpira Bita Geramizadeh Baharak Khadang Afsaneh Moaddeb Mojgan Ghaedi Tahereh Heidari Ardeshir Torab Alireza Salah Saeid Amirzadeh Zahra Jowkar Davood Mehrabani Samad Amini-Bavil-Olyaee Mohammad Ali Dehyadegari | 2008 | World Journal of Gastroenterology2008，14，10： | 4 |
| 9 | Robust control approach for handling matched and/or unmatched uncertainties in port-controlled Hamiltonian systems显示文摘This study considers the problem of robust interconnection and damping assignment passivity-based control approach(IDA-PBC)for underactuated mechanical systems from two points of view.First,the robustness of IDA-PBC in the presence of non-vanishing matched and unmatched uncertainties is analysed and sufficient conditions are derived to ensure ultimate boundedness of system.Second,the robust control design is provided by adding a new control input to the former controller designed by IDA-PBC,such that asymptotic stability of the closed-loop system in the face of non-vanishing matched uncertainties is fulfilled.Finally,the proposed robust controller is evaluated through simulations of two practical examples,i.e.an inertia wheel pendulum and a single-link elastic joint robot.The simulation outcomes clearly reveal the effectiveness of the presented robust controller. | Tahereh Binazadeh Mahsa Karimi Ali Reza Tavakolpour-Saleh | 2019 | IET Cyber-Systems and Robotics2019，1，3： | 2 |
| 10 | A Randomized,Double Blinded,Placebo-Controlled Clinical Trial of Silymarin in Ulcerative Colitis显示文摘Objective:To evaluate the clinical efficacy of silymarin in ulcerative colitis(UC) patients.Methods:A randomized double blinded placebo-controlled clinical trial was conducted in 80 UC patients whose disease had been documented and were in remission state between September 2009 and October 2010.Patients were assigned to silymarin group(42 cases) and placebo group(38 cases) using a random number table.Either silymarin(140 mg) or placebo(lactose mono-hydrate,corn starch magnesium stearate) tablets were given once daily for 6 months along with their standard therapy.The efficacies were assessed by disease activity index(DAI),frequency difference of the disease flare-up,and paraclinical data.Results:Ten patients(4 in the silymarin group due to nausea and 6 in the placebo group due to disease flare-up and abdominal pain)discontinued the study.An improvement in hemoglobin level(11.811.6 g/dL vs.13.4 ±1.2 g/dL,P<0.05)and erythrocyte sedimentation rate(23.7±11.5 mm/h vs.10.8±3.2 mm/h,P<0.05) was observed in the silymarin group but not in the placebo group.DAI significantly decreased in the silymarin group and reached from 11.3 ±3.5 to 10.7 ±2.8(P<0.05).Thirty-five out of 38 patients in the silymarin group were in complete remission with no flare-up after 6 months as compared to 21 out of 32 patients in the placebo group(P=0.5000).Conclusion:Silymarin as a natural supplement may be used in UC patients to maintain remission. | Mansoor Rastegarpanah Reza Malekzadeh Homayoun Vahedi Maryam Mohammadi Elham Elahi Meghedi Chaharmahali Tahereh Safarnavadeh Mohammad Abdollahi | 2015 | Chinese Journal of Integrative Medicine2015，21，12： | 2 |
| 11 | Seroepidemiology of hepatitis C and its risk factors in Khuzestan Province, South-West of Iran:A case-control study显示文摘瞄准:为丙肝感染的传播评估可能的风险因素并且与丙肝感染在病人之中分析流行病学、临床的模式的特征。方法:在一个五年的时期期间,代表性的研究在指的 HCV 积极个人之中被进行阿瓦十 JundiShapour 大学医院(AJSUH ) 和到 2003 年 9 月 1 日的从 1999 年 9 月 1 日的肝炎诊所。控制组由指的第一次供血者组成了地区性的输血组织。连接酶的免疫吸着剂试金和 recombinant 免疫污点试金反肝炎 C 病毒(HCV ) 测试为二个组被执行。积极浆液标本为 HCV RNA 是用聚合酶链反应(PCR ) 的 retest 编辑。风险因素用一张问询表被评估。在感染的题目之中的报导风险因素(“ HCV 积极”) 与从来没暴露的题目的那些相比(“ HCV 否定”) 到 HCV。结果:514 个题目的一个总数为 HCV, 254 是 HCV 积极的被学习, 260 个 HCV 否定的施主包括了控制组。病人的吝啬的年龄是 28.4 (Std 15.22 ) 年。HCV 积极的题目是更可能的具有男性(63% 对 37%) 。输送 132 (52%) ,非静脉内(n-i.v.) 药滥用和 i.v 药滥用 37 (14.5%) ,血液透析 25 (10%) ,在战争和婚外的性欲活动(2.4%) 收到创伤,(3.6%) 纹身被发现是是 HCV 积极的独立风险因素。没有明显的风险因素能在 29 被表明(11.2%) 积极案例。结论:我们输送和 i.v 药滥用和血液透析的历史是重要的数据 indicate 在我们的区域和血屏蔽的那更小心的 pretransfusion 为 HCV 感染冒因素的风险因为 anti-HCV 必须在我们的血库被介绍。在某些生活方式模式的改进,和在这个区域的习俗可能是必要的阻止感染的传播。 | Eskandar Hajiani Jalal Hashemi Rahim Masjedizadeh Ali Akbar Shayesteh Esmail Idani Tahereh Rajabi | 2006 | World Journal of Gastroenterology2006，12，30： | 2 |
| 12 | Synthesis,spectral studies,thermal behavior,and antibacterial activity of Ni(Ⅱ),Cu(Ⅱ),and Zn(Ⅱ) complexes with an ONO tridentate Schiff base显示文摘三新转变金属建筑群与一个 Schiff 底被综合了, 3-(2-hydroxy-5-chlorophenylimino )-1,3-diphenylpropen-1-one。在所有建筑群 Schiff 底是完全 deprotonated 并且经由酉分、烯醇的氧和 imine 氮作为有三齿的 ligand 协调了到金属。建筑群的热分解被 thermogravimetry 学习了。在里面 Schiff 底和他们的建筑群的 vitro 抗菌剂活动被评估了并且与标准药相比。 | Mohammad Azarkish Tahereh Sedaghat | 2012 | Chinese Chemical Letters2012，23，9： | 2 |
| 13 | Hepatitis C virus transmission and its risk factors within families of patients infected with hepatitis C virus in southern Iran:Khuzestan显示文摘AIM: To determine whether hepatitis C virus (HCV) infection of index cases increases intrafamilial transmission (sexual and nonsexual contacts) of HCV. METHODS: In a case-control descriptive study we enrolled 300-household contacts of 60 index cases (40 males and 20 females) of HCV infection and 360 pair- matched controls in Ahwaz JundiShapour University Hospitals from August 1, 1998 to September 1, 2003. The control group consisted of first time blood donors referred to the Regional Blood Transfusion Organization. Serum samples and demographic data and a medical history including the existence of risk factors for HCV (after a questionnaire on the risk factors for parenteral exposure) were obtained from each subject. Antibodies to HCV were detected employing a commercially available second-generation enzyme immunoassay (EIA, Abbott Ⅱ). Positive serum specimens were retested using a second-generation recombinant immunoblot assay (RIBA-2) and a polymerase chain reaction for HCV RNA. Data analysis was carried out for intra-household clustering. RESULTS: Only 4 of 300 (1.33%) cases of household contacts without percutaneous risk factors were positive for HCV Ab while the remaining 296 family contacts were negative for anti-HCV. The mean age of the index cases was 28.4 (Std 15.22) years. The anti-HCV prevalences in parents, spouses, children of the index cases were 0.87% (1/115), 3.39% (2/59)) and 0.79% (1/126), respectively. Among couple partners negative for anti-HCV antibodies, the mean duration of the sexual relationship was 6 years.The two-couple partners positive for anti-HCV antibodies married the index cases for longer than 15 years. The prevalence of positive HCV Ab among household contacts (1.33%) was not significantly higher than that in the controls (1%) (P > 0.06). CONCLUSION: Intrafamilial transmission of HCV is not the significant transmission route and sexual transmission does not seem to play a role in the intrafamilial spread of HCV infection. Intrafamilial transmission of HCV is possible but occurs at a low rate. | Eskandar Hajiani Rahim Masjedizadeh Jalal Hashemi Mehrdad Azmi Tahereh Rajabi | 2006 | World Journal of Gastroenterology2006，12，43： | 2 |
| 14 | Nuclephilic ring opening of epoxides promoted by multi-site phase-transfer catalyst:An efficient and eco-friendly route to synthesis of β-hydroxythiocyanate显示文摘A highly effective and mild protocol for ring opening of epoxides with NH4SCN in the presence of catalytic amount of a multisite phase-transfer catalyst,α,α′,α″-N-hexakis(triethylammoniummethylene chloride)-melamine,is developed.A variety ofβ-hydroxy thiocyanates as important intermediates in agricultural and pharmaceutical chemistry were obtained in high yields with excellent regioselectivity and in short reaction times. | Ali Reza Kiasat Roya Mirzajani Haji Shalbaf Tahereh Tabatabaei | 2009 | Chinese Chemical Letters2009，20，9： | 2 |
| 15 | Effect of elemental molar ratio on the synthesis of higher alcohols over Co-promoted alkali-modified Mo_2C catalysts supported on CNTs显示文摘A series of molybdenum carbide catalysts promoted by potassium and cobalt,supported on carbon nanotubes(CNTs) were prepared by carbothermal hydrogen reduction method using CNTs as a carbon precursor.Firstly,molybdenum and cobalt were loaded by co-precipitation method,and then potassium and additional molybdenum were impregnated to previous resultant.Different Mo/Co and K/Co molar ratio were used in catalyst synthesis.All the catalysts were characterized by ICP,BET,TEM,TPR,XRD and XPS,and the catalysts performances for higher alcohols synthesis(HAS) were investigated in a fixed-bed micro-reactor.The maximum selectivity to higher alcohols(C2+OH) was obtained at Mo/Co and K/Mo molar ratios of 1.66 and 0.6,respectively.XRD results confirmed the formation of K-Mo-C site and Co3Mo3 C phase that might play important role in producing C2+OH. | Rohollah M.Kiai Tahereh Nematian Ahmad Tavasoli Ali Karimi | 2015 | Journal of Energy Chemistry2015，24，3： | 2 |
| 16 | Immunophenotypic subtyping of leukemic cells from Iranian patients with acute lymphoblastie leukaemia: association to disease outeome显示文摘 | Hossein A O Mahdi S Tahereh S | 2007 | Iran J Immunol2007，4，1： | 1 |
| 17 | Highly selective thiocyanate poly(vinyl chloride) membrane electrode based on cadmium Schiff's base complex显示文摘 | Mohammad Reza Ganjali Tahereh Poursaberi Fatemeh Basiripour | 2001 | Fresenius J Anal Chem2001，370，： | 1 |
| 18 | Batch extraction of gold(III) ions from aqueous solutions using emulsion liquid membrane via facilitated carrier transport显示文摘 | All Kargari Tahereh Kaghazehi Morteza Sohrabi | 2004 | Journal of Membrane Science2004，233，12： | 1 |
| 19 | Training and validation ofstandardized patients for evaluation of general practitioners'performance in management of obesity and overweight显示文摘 | Tahereh C3iangiz Sepideh Jamshidian | 2014 | Adv Biomed Res2014，，3： | 1 |
| 20 | Fungal keratitis in patients with corneal ulcer in Sari,Northern Iran显示文摘 | Tahereh S Nowroozpoor-Dailami K Moaddel-Haghighi T | 2006 | Arch Iran Med2006，9，： | 1 |
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