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42篇 您的检索式：作者名="Tabor L"

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	题名	作者	年代	出处	被引量
1	Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source显示文摘BACKGROUND The trans-fat containing AMLN(amylin liver non-alcoholic steatohepatitis,NASH)diet has been extensively validated in C57BL/6J mice with or without the Lep^ob/Lep^ob(ob/ob)mutation in the leptin gene for reliably inducing metabolic and liver histopathological changes recapitulating hallmarks of NASH.Due to a recent ban on trans-fats as food additive,there is a marked need for developing a new diet capable of promoting a compatible level of disease in ob/ob and C57BL/6J mice.AIM To develop a biopsy-confirmed mouse model of NASH based on an obesogenic diet with trans-fat substituted by saturated fat.METHODS Male ob/ob mice were fed AMLN diet or a modified AMLN diet with trans-fat(Primex shortening)substituted by equivalent amounts of palm oil[Gubra amylin NASH,(GAN)diet]for 8,12 and 16 wk.C57BL/6J mice were fed the same diets for 28 wk.AMLN and GAN diets had similar caloric content(40%fat kcal),fructose(22%)and cholesterol(2%)level.RESULTS The GAN diet was more obesogenic compared to the AMLN diet and impaired glucose tolerance.Biopsy-confirmed steatosis,lobular inflammation,hepatocyte ballooning,fibrotic liver lesions and hepatic transcriptome changes were similar in ob/ob mice fed the GAN or AMLN diet.C57BL/6J mice developed a mild to moderate fibrotic NASH phenotype when fed the same diets.CONCLUSION Substitution of Primex with palm oil promotes a similar phenotype of biopsyconfirmed NASH in ob/ob and C57BL/6J mice,making GAN diet-induced obese mouse models suitable for characterizing novel NASH treatments.	Michelle L Boland Denise Oro Kirstine S T■lb■l Sebastian T Thrane Jens Christian Nielsen Taylor S Cohen David E Tabor Fiona Fernandes Andrey Tovchigrechko Sanne S Veidal Paul Warrener Bret R Sellman Jacob Jelsing Michael Feigh Niels Vrang James L Trevaskis Henrik H Hansen	2019	World Journal of Gastroenterology2019，25，33：	3
2	Bulked seregant analysis identifies markers linked to Melampsora medusae resistance in Populus deltoides显示文摘	TABOR G M KUBISIAK T L KLOPFENSTEIN N B	2000	Phytopathology2000，90，：	1
3	Synthesis of (S) -jamaicamide C carboxylic acid 显示文摘	Graf K M Tabor M G Brown M L	2009	Org Lett2009，11，23：	1
4	Oestrogen-mediated cardioprotection following ischaemia and reperfusion is mimicked by an oestrogen receptor (ER)alpha agonist and unaffected by an ER beta antagonist显示文摘	Jeanes H L Tabor C Black D	2008	Endocrinol2008，197，3：	1
5	Tw in pregnancy the role of ultrasound in managent显示文摘	Sperling L Tabor A	2001	Acta Obstet Gynecol Scand2001，80，4：	1
6	Global and local optimization using radial basis function response surface models显示文摘	McDonald D B Grantham W J Tabor W L	2007	Applied Mathematical Modeling2007，31，：	1
7	Global and Local Optimization Using Ra-dial Basis Function Response Surface Models显示文摘	MCDONALD Dale B GRANTHAM Walter J TABOR Wayne L		0，，10：	1
8	Global and Local Optimization Using Radial Basis Function Response Surface Models显示文摘	McDonald D B Grantham W J Tabor W L	2007	Applied Mathematical Modelling2007，31，10：	1
9	Twin pregnancy: the role of ultrasound in management显示文摘	Sperling L Tabor A	2001	Acta Obstet Gynecol Scand2001，80，4：	1
10	The adhesion and strength proper- ties of iee显示文摘	Raraty L E Tabor D	1958	Proceedings of the Royal Society of Lon- don Series A Mathematical and Physical Sciences1958，245，1241：	1
11	Twin pregnancy: the role of ultrasound in management显示文摘	Sperling L Tabor A	2001	Acta Obstet Gynecol Scand2001，80，4：	1
12	The evaluation of resin systems for concrete re- pair显示文摘	TABOR L J	1978	Mag Concr Res1978，30，105：	1
13	Twin pregnancy: the role of ultrasound in management显示文摘		2001	Acta Obstet Gynecol Scand2001，80，：	1
14	Global and local optimization using radial basis function re- sponse surface models 显示文摘	MCDONALD D B GRANTHAM W J TABOR W L	2007	Applied Mathematical Model- ling2007，31，10：	1
15	Twin pregnancy : the role of ultrasound in management显示文摘	Sperling L Tabor A	2001	Acta Obstet Gynecol Scand2001，80，4：	1
16	Homeostatic utility control显示文摘	Schweppe F C Tabors R D Kirtley J L	1980	IEEE Trans on Power Apparatus and Systems1980，50，5：	1
17	Homeostatic Utility Control显示文摘	Sehweppe F C Tabors R D Kirle J L	1980	IEEE Transaction on Power Apparatus and Systems1980，99，3：	1
18	Homeo-static utility control 显示文摘	Schweppe F C Tabors R D Kirtley J L	1980	IEEE Trans PAS1980，99，3：	1
19	Twin pregnancy: the role of ultrasound in management显示文摘	Sperling L Tabor A	2001	Acta Obstetricia et Gynecologica Scandinavica2001，80，4：	1
20	Quantum maps显示文摘	Berry M V Balazs N L Tabor M	1979	Annals of Physics1979，122，1：	1

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