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| 1 | Aspects of the non-pharmacological treatment of irritable bowel syndrome显示文摘Irritable bowel syndrome(IBS) is one of the most commonly diagnosed gastrointestinal conditions. It represents a significant healthcare burden and remains a clinical challenge. Over the years IBS has been described from a variety of different perspectives; from a strict illness of the gastrointestinal tract(medical model) to a more complex multi-symptomatic disorder of the brain-gut axis(biopsychosocial/psychosomatic model). In this article we present aspects of the pathophysiology and the non-pharmacological treatment of IBS based on current knowledge. Effects of conditioned stress and/or traumatic influences on the emotional system(top-down) as well as effects on the intestine through stressors,infection,inflammation,food and dysbiosis(bottom-up) can affect braingut communication and result in dysregulation of the autonomic nervous system(ANS),playing an important role in the pathophysiology of IBS. Conditioned stress together with dysregulation of the autonomic nervous system and the emotional system may involve reactions in which the distress inside the body is not recognized due to low body awareness. This may explain why patients have difficulty identifying their symptoms despite dysfunction in muscle tension,movement patterns,and posture and biochemical functions in addition to gastrointestinal symptoms. IBS shares many features with other idiopathic conditions,such as fibromyalgia,chronic fatigue syndrome and somatoform disorders. The key to effective treatment is a thorough examination,including a gastroenterological examination to exclude other diseases along with an assessment of body awareness by a body-mind therapist. The literature suggests that early interdisciplinary diagnostic cooperation between gastroenterologists and body-mind therapists is necessary. Re-establishing balance in the ANS is an important component of IBS treatment. This article discusses the current knowledge of body-mind treatment,addressing the topic from a practical point of view. | Elsa Maria Eriksson Kristina Ingrid Andrén Goran Karl Kurlberg Henry Ture Eriksson | 2015 | World Journal of Gastroenterology2015，21，40： | 6 |
| 2 | Antioxidants vitamin E and C attenuate hepatic fibrosis in biliary-obstructed rats显示文摘AIM: To investigate whether antioxidants vitamin E and C can retard development of hepatic fibrosis in the bili- ary-obstructed rats. METHODS: Fifty Wistar albino rats were randomly as- signed to 5 groups (10 rats in each). Bile duct was liga- ted in 40 rats and they were treated as follows: group vitC, vitamin C 10 mg/kg sc daily; group vitE, vitamin E 15 mg/kg sc daily; group vitEC, both of the vitamins; bile duct-ligated (BDL, control) group, physiological saline sc. The fifth group was assigned to sham operation. At the end of fourth week, the rats were decapitated, and hepatic tissue biochemical collagen content and collagen surface area were measured. Hepatic tissue specimens were histopathologically evaluated according to Scheuer system. Serum hyaluronate levels were measured by ELISA method. RESULTS: Despite being higher than sham group, he- patic collagen level was significantly decreased in each of the vitC, vitE and vitEC groups (32.7 ± 1.2, 33.8 ± 2.9, 36.7 ± 0.5 μg collagen/mg protein, respectively) compared to BDL (48.3 ± 0.6 mg collagen/g protein) (P < 0.001 for each vitamin group). Each isolated vitamin C, isolated vitamin E and combined vitamin E/C supp-lementation prevented the increase in hepatic collagen surface density (7.0% ± 1.1%, 6.2% ± 1.7%, 12.3% ± 2.0%, respectively) compared to BDL (17.4% ± 5.6%) (P < 0.05 for each). The same beneficial effect of vitamin C, vitamin E and combined vitamin E/C treatment was also observed on the decrease of serum hyaluronate levels compared to BDL group (P < 0.001). The relative liver and spleen weights, serum transaminases, cholestatic enzymes, bilirubins and histopathological inflammation scores were not different between the antioxidant treat- ment groups and the control. However, fibrosis staging scores were obviously reduced only in the vitamin E/C combination group (vit EC: 2.4 ± 0.8 vs BDL: 3.1 ± 0.7; P < 0.05). CONCLUSION: Each antioxidant vitamin E, vitamin C and their combination retard hepatic fibrosis in biliary-obs- tructed rats. Oxidative stress may play a role in the patho- genesis of hepatic fibrosis in secondary biliary cirrhosis. | Ali Riza Soylu Nurettin Aydogdu Umit Nusret Basaran Semsi Altaner Orhan Tarcin Nursal Gedik Hasan Umit Ahmet Tezel Gulbin Dokmeci Huseyin Baloglu Mevlut Ture Kemal Kutlu Kadir Kaymak | 2006 | World Journal of Gastroenterology2006，12，42： | 4 |
| 3 | Novel associations between rhizobial populations and legume species within the genera Lathyrus and Oxytropis grown in the temperate region of China显示文摘Fifty rhizobial isolates of Lathyrus and Oxytropis collected from northern regions of China were studied in their genotypic characterization based upon analyses of ARDRA, 16S-23S IGS PCR-RFLP, TP-RAPD, MLEE, sequences of 16S rDNA gene and housekeeping genes of atpD, recA and glnII. The results demonstrated that most of the Lathyrus rhizobia belonged to Rhizobium and most of the Oxytropis rhizobia belonged to Sinorhizobium. A novel group of Rhizobium sp. I and S. meliloti were identified as the main microsymbionts respectively associated with Lathyrus and Oxytropis species in the collection area, which were new associations between rhizobia and the mentioned hosts. This study also provides new evidence for biogeography of rhizobia. | SUI XinHua, HAN LiLi, WANG EnTao, JIANG Feng, LIU YiHai & CHEN WenXin State Key Laboratory for AgroBiotechnology, Key Laboratory of Agro-Microbial Resource and Application, Ministry of Agricul- ture/College of Biological Sciences, China Agricultural University, Beijing 100193, China | 2009 | Science China(Life Sciences)2009，52，2： | 2 |
| 4 | A High- efficiency Carrier Estimator for OFDM Communications显示文摘 | Liu H Tureli U | 1998 | IEEE Communication Letters1998，2，4： | 2 |
| 5 | Deterministic multiuser carrier-frequency offset estimation for interleaved OFDMA uplink显示文摘 | Z Cao U Tureli Y D Yao | 2004 | IEEE Trans Commun2004，52，9： | 1 |
| 6 | Low-complexity nonlinear least squares earlier offset estimator for OFDM: identifiability, diversity and performance 显示文摘 | Tureli U Honan P J Liu H | 2004 | Signal Processing IEEE Transactions on2004，52，9： | 1 |
| 7 | Measurement of caffeine in coffee beans with UV/Vis spectrometer显示文摘 | BELAY A TURE K REDI M | | 0，，01： | 1 |
| 8 | OFDM blind carrier offset estimation, ESPRIT显示文摘 | Tureli U Liu H Zoltowski M D | 2000 | IEEE Trans on Communication2000，48，9： | 1 |
| 9 | The chemical basis of morphogenesis显示文摘 | Turing A M | 1952 | Biologi- cal Sciences: Series B1952，237，641： | 1 |
| 10 | Ahigh-efficiency carriers estimator for OFDM communications显示文摘 | Liu H Tureli U | 1998 | IEEE Communication Letters1998，2，4： | 1 |
| 11 | Computing Machinery and Intelligence显示文摘 | A M Turing | 1950 | Mind1950，59，236： | 1 |
| 12 | The chemical basis of morphogenesis显示文摘 | Turing A M | 1952 | Philosophical Transactions of the Royal Society London1952，237，： | 1 |
| 13 | Computing machinery and intelligence 显示文摘 | TURING A M | 1950 | Mind1950，5，9： | 1 |
| 14 | Microsurgery of insular gliomas Part II: opening of sylvian fissure显示文摘 | Yasargil MC Krisht AF Ture U | 2002 | Contempor Neurosurgery2002，24，1： | 1 |
| 15 | Thyroid fine needle aspira- tion biopsy: do we really need an on-site cytopathologist? 显示文摘 | Cengic I Tureli D Ahiskali R | 2014 | Eur J Radiol2014，83，4： | 1 |
| 16 | The microsurgical anatomy of the glossopharyngeal nerve with respect to the jugular foramen lesions显示文摘 | Mehmet Faik Ozveren Ug Ur TUre | 2004 | Neurosurg Focus2004，17，2： | 1 |
| 17 | Aspects of DNA Complementarity 显示文摘 | SALOMAA A TURING WATSON-CRICK LINDENMAYER | 1998 | Springer: Unconventional Models of Computation1998，76，4： | 1 |
| 18 | Low-complexity orthogonal spectral signal construction for generalized OFDMA uplink with frequency synchronization errors 显示文摘 | Cao Z Tureli U Yao Y D | 2007 | IEEE Transactions on Vehicular Technology2007，56，3： | 1 |
| 19 | OFDM blind carrier offset estimation:estprit显示文摘 | Tureli U Liu H Zoltowski M D | 2000 | IEEE Trans2000，48，9： | 1 |
| 20 | The chemical basis of morphogenesis 显示文摘 | Turing A | 1952 | Philosophical Transactions of the Royal Society of London1952，237，： | 1 |
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