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| 1 | Carcinogenic Helicobacter pylori in gastric pre-cancer and cancer lesions: Association with tobacco-chewing显示文摘AIM:To investigate the low gastric cancer incidence rate relative to the highly prevalent Helicobacter pylori(H.pylori)infection;data relevant to H.pylori infection during gastric carcinogenesis in Indian patients is currently lacking.METHODS:The present study examines the prevalence of H.pylori infection in DNA derived from 156endoscopic gastric biopsies of different disease groups that represent gastric pre-cancer[intestinal metaplasia(n=15),dysplasia(n=15)],cancer[diffuse adenocarcinoma(n=44),intestinal adenocarcinoma(n=21)],and symptomatic but histopathologically-normal controls(n=61).This was done by generic ureC polymerase chain reaction(PCR)and cagA-specific PCR that could specifically identify the carcinogenic H.pylori strain.RESULTS:Our analysis showed the presence of H.pylori infection in 61%of symptomatic histopathologically-normal individuals,however only 34%of control tissues were harboring the cagA+H.pylori strain.A similar proportion of H.pylori infection(52%)and cagA(26%)positivity was observed in the tumor tissue of the gastric cancer group.In comparison,H.pylori infection(90%)and cagA positivity(73%)were the highest in gastric pre-cancer lesions.In relation to tobacco and alcohol abuse,H.pylori infection showed an association with tobacco chewing,whereas we did not observe any association between tobacco smoking or alcohol abuse with prevalence of H.pylori infection in the tissue of any of the patient groups studied.CONCLUSION:High incidence of H.pylori infection and carcinogenic cagA positive strain in pre-cancer lesions during gastric carcinogenesis may be | Arvind Pandey Satyendra Chandra Tripathi Sutapa Mahata Kanchan Vishnoi Shirish Shukla Sri Prakash Misra Vatsala Misra Suresh Hedau Ravi Mehrotra Manisha DwivediZ Alok C Bharti | 2014 | World Journal of Gastroenterology2014，20，22： | 4 |
| 2 | Morphology and physical prop-erties of closed-cell microcellular ethylene–propylene–diene terpolymer(EPDM)rubber vulcanizates:effect of blo-wing agent and carbon black loading显示文摘 | Guriya K C Tripathy D K | 1996 | Journal of AppliedPolymer Science1996，62，1： | 1 |
| 3 | On a new class of sequences related to the space l^p显示文摘 | TRIPATHY B C SEN M | 2002 | Tamkang J Math2002，33，2： | 1 |
| 4 | Serum insulin and lipid profile in normal pregnant and pregnancy-induced hypertensive women from North India显示文摘 | Tripathy C | 1999 | Aust NZ J Obstet Gynaecol1999，39，： | 1 |
| 5 | Planting systems on lodging behavior, yield components, and yield of irrigated spring breadwheat显示文摘 | Tripathi S C Sayre K D Kaul J N | 2005 | Crop Sci2005，45，： | 1 |
| 6 | Male germ cell development: turn- ing on the apoptotic pathways 显示文摘 | Tripathi R:Mishra DP Shaha C | 2009 | J Reprod hnmunol2009，83，12： | 1 |
| 7 | Glil protein reguates ti S-phase checkpoint in tumor cells via Bid protein, and its inhibitior sensitizes to DNA topoisomerase I inhibitors显示文摘 | Tripathi K Mani C Barnett R | 2014 | J Biol Chem2014，289，31： | 1 |
| 8 | Self-generated magnetic field in an amplitude modulated laser filament in a plasma显示文摘 | Tripathi V K Liu C S | 1994 | Phys Plasmas1994，1，4： | 1 |
| 9 | Temperature-stress-induced impairment of chlorophyll biosynthetic reactions in cucumber and wheat显示文摘 | TEWARI A K TRIPATHY B C | 1998 | Plant physiology1998，117，3： | 1 |
| 10 | Characterization of iron-bearing minerals in Giril lignite from Rajasthan and study of their decomposition during combustion using ^57Fe Moessbauer spectroscopy显示文摘 | Verma H C Tripathi R P | 2000 | Fuel2000，79，6： | 1 |
| 11 | Palladlum-catalysed reduction of molybdenum trioxide by hydrogen显示文摘 | Bond G C Tripathi J B P | 1974 | J Less-Common Met1974，36，12： | 1 |
| 12 | ITS-RFLP fingerprinting and molecular marker for detection of Fusarium oxysporum f sp ciceris显示文摘 | Dubey S C Tripathi A Singh S R | 2010 | Folia Microbiol (Praha)2010，55，6： | 1 |
| 13 | Protection of chickens against highly pathogenic avian influenza virus(H5N2) by recombinant fowlpox viruses显示文摘 | Schnitzlein W M Tripathy D N | 1991 | Avian Dis1991，35，2： | 1 |
| 14 | Antioxidant and antimuta- genic effect of quercetin against DEN induced hepatotoxicity in rat 显示文摘 | Gupta C Vikram A Tripathi D N | 2010 | PhytotherRes2010，24，1： | 1 |
| 15 | First line, single-agent Herceptin (trastuzumab) in metastatic breast cancer : a pre-liminary report显示文摘 | Vogel C Cobleigh MA Tripathy D | 2001 | Eur J Cancer2001，37，： | 1 |
| 16 | Planting systems on lodging behavior, yield components, and yield of irrigated spring bread wheat 显示文摘 | Tripathi S C Sayre K D Kaul J N | 2005 | Crop Science2005，45，： | 1 |
| 17 | Development of novel po- lymeric flocculant based on grafted sodium alginate for the treatment of coal mine wastewater 显示文摘 | Tripathy T Karmakar N C Singh R P | 2001 | Journal of Applied Polymer Science2001，82，2： | 1 |
| 18 | A modifiedTLS-ESPRIT-based method for low-frequency mode identificationin power systems utilizing synchrophasor measurements 显示文摘 | TRIPATHY P’SRIVASTAVA S C SINGH S N | 2011 | IEEE Transactions on Power Systems2011，26，2： | 1 |
| 19 | Application of PCR fingerprinting techniques for identification and discrimina- tion of Salmonella isolates 显示文摘 | ANJALI T TRIPATHI A K VERMA S C | 2001 | Current Science2001，80，8： | 1 |
| 20 | Development of a pilot-scale production process and characterization of a recombinant Japanese encephalitis virus envelope domain III protein expressed in Escherichia coli 显示文摘 | Tripathi N K Shrivastava A Biswal K C | 2012 | Appl Microbiol Biotechnol2012，95，5： | 1 |
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