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| 1 | Efficacy of sequential treatment of HCT116 colon cancer monolayers and xenografts with docetaxel,flavopiridol,and 5-fluorouracil显示文摘瞄准:有 docetaxel, flavopiridol,或 5 氟尿嘧啶(5-FU ) 的稳固的肿瘤的临床的治疗经常遇到不受欢迎的副作用和药抵抗。在 modulating chemosensitivity 并且更好与 docetaxel, flavopiridol,或 5-FU 评估联合治疗的潜在的角色的目的理解他们怎么可能临床上被使用的这研究。方法:HCT116 结肠癌房间在几不同行政时间表在试管内与 docetaxel, flavopiridol,和 5-FU 被对待,顺序或同时。房间幸存被 MTT 试金测量。caspase-3 的活动被 caspase-3 试金决定,软琼脂殖民地试金被用来在软琼脂测试 HCT116 房间的菌落形成。我们也建立了异种皮移植模型扩大在试管内观察到一个在活体内系统。结果:当人的结肠癌 HCT116 房间为 flavopiridol 为另一 24 h 为 24 h 和 5-FU 跟随的 1 h 与 docetaxel 被对待时,最大的细胞毒性被发现。这顺序的联合治疗不仅与另外的联合治疗相比更强烈禁止肿瘤细胞生长而且显著地在软琼脂减少菌落形成并且扩充 HCT116 细胞的 apoptosis。docetaxel 定序以后由 flavopiridol 跟随了 1 h,以后在异种皮移植模型由 5-FU 跟随了 24 h,也导致了推迟的肿瘤生长和更高的幸存率。结论:当把 docetaxel 与 flavopiridol 和 5-FU 相结合时,这些结果强调一张行政时间表的重要性,提供对它在临床的试用的发展的基本原理解释。 | Jun GUO An-wu ZHOU Yu-cai FW Udit N VERMA Debu TRIPATHY Eugene P FRENKEL Carlos R BECERRA | 2006 | Acta Pharmacologica Sinica2006，27，10： | 4 |
| 2 | The PPAR gamma agonist Pioglitazone improves anatomical and locomotor recovery after rodent spinal cord injury显示文摘 | McTigue DM Tripathi R Wei P | 2007 | Exp Neurol2007，205，2： | 1 |
| 3 | Salmonella pathogenicity island 2 influences both systemic Salmonellosis and Salmonella in duced enteritisincalves显示文摘 | Bispham J Tripathi B N Watson P R | 2001 | Infection and Immunity2001，69，： | 1 |
| 4 | Perspectives for chitosan based antimicrobial film in food applications显示文摘 | Durra P K Tripathi S Mehrotra G K | 2009 | Food ChemistiT2009，114，： | 1 |
| 5 | Organic-inorganic nanocomposite polymer electrolyte membranes for fuel cell applications显示文摘 | Tripathi B P Shahi V K | 2011 | Progress in Polymer Science2011，36，7： | 1 |
| 6 | Organic-inorganic nanocomposite polymer electrolyte membranes for fuel cell applications显示文摘 | Tripathi B P Shahi V K | 2011 | Progress in Polymer Science2011，36，7： | 1 |
| 7 | Decomposition of kitchen waste amended with cow manure using an epigeic species (Eisenia fetida ) and an anecic species (Lampito mauritii) 显示文摘 | Tripathi G Bhardwaj P | 2004 | Bioresource Technology2004，92，2： | 1 |
| 8 | Spec-trum Challenges and Solutions by Cognitive Radio: anOverview 显示文摘 | SRIDHARA K CHANDRA A TRIPATHI P S M | 2008 | Wireless Personal Communications2008，45，3： | 1 |
| 9 | Preparation and physicoehemical evaluation of ehitosan/poly (vinyl alcohol )/ pectin ternary film for food - packaging applications 显示文摘 | Tripathi S Mehrotra G K Dutta P K | 2010 | Carbohydrate Polymers2010，79，3： | 1 |
| 10 | Influence of properties of bituminous binders on the strength of formed coke显示文摘 | SHARMA A K DAS B P TRIPATHI P S M | 2002 | Fuel Processing Technology2002，75，3： | 1 |
| 11 | Elevation of free fatty acid induced inflammation and impairs vascular reactivity in healthy subjects显示文摘 | MOHANTY P DHINDSA S | 2003 | Diabetes2003，52，12： | 1 |
| 12 | Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects显示文摘 | Tripathy D Mohanty P Dhindsa S | 2003 | Diabetes2003，52，12： | 1 |
| 13 | Performance evaluation of cement stabilized fly ash-GBFS mixes as a high- way construction material显示文摘 | SINGH S P TRIPATHY D P RANJITH P G | 2008 | Waste Management2008，28，： | 1 |
| 14 | Glomalin: An arbuscular mycorrhizal fungal soil protein 显示文摘 | Singh P K Singh M Tripathi B N | 2012 | Pedobiologia2012，51，2： | 1 |
| 15 | Intracranial epidermoid-a 10-year study显示文摘 | Roy K Bhattacharyya AK Tripathy P | 2008 | J Indian Med Assoc2008，106，7： | 1 |
| 16 | Photon induced positron annihilation spectroscopy:a nondestructive method for assay of defects in large engineering materials显示文摘 | Pujari P K Sudarshan K Tripathi R | 2012 | Nuclear Instruments and Methods in Physics Research2012，270，： | 1 |
| 17 | Antigen mimicry by an anti-idiotypic antibody single chain variable fragment显示文摘 | TRIPATHI P QIN H DENG S | 1998 | Molecular Immunology1998，35，13： | 1 |
| 18 | Elevation of free fatty acids induces inflammation and impairs vascular reactivity in healthy subjects显示文摘 | Tripathy D Mohanty P Dhindsa S | 2003 | Diabetes2003，52，12： | 1 |
| 19 | STUDY OF HEAVY METALS IN WHEAT AND PADDY GRAINS显示文摘 | BEHERA S N TRIPATHY P S M | 1999 | International Journal of PIXE1999，9，34： | 1 |
| 20 | Chemical processing of a low grade molybdenite concentrate to recover molybdenum 显示文摘 | Tripathy P K Rakhasia R H | 2005 | Mineral Processing & Extractive Metallurgy2005，，： | 1 |
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