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		题名	作者	年代	出处	被引量
	1	Adrenomedullin in cirrhotic and non-cirrhotic portal hypertension显示文摘AIM:Adrenomedullin (ADM) is a potent vasodilator peptide.ADM and nitric oxide (NO) are produced in vascular endothelial cells. Increased ADM level has been linked to hyperdynamic circulation and arterial vasodilatation in cirrhotic portal hypertension (CPH). The role of ADM in non-cirrhotic portal hypertension (NCPH) is unknown, plasma ADM levels were studied in patients with NCPH, compensated and decompensated cirrhosis in order to determine its contribution to portal hypertension (PH) in these groups.METHODS: There were 4 groups of subjects. Group 1consisted of 27 patients (F/M: 12/15) with NCPH due to portal and/or splenic vein thrombosis (mean age: 41±12years), group 2 consisted of 14 patients (F/M: 6/8) with compensated (Child-Pugh A) cirrhosis (mean age: 46±4),group 3 consisted of 16 patients (F/M: 6/10) with decompensated (Child-Pugh C) cirrhosis (mean age: 47±12).Fourteen healthy subjects (F/M: 6/8) (mean age: 44±8) were used as controls in Group 4. ADM level was measured by ELISA. NO was determined as nitrite/nitrate level by chemoluminescence.RESULTS: Adl level in Group 11 (236±61.4 pg/mL) was significantly higher than that in group 2 (108.4±28.3 pg/mL)and group 4 (84.1±31.5 pg/mL) (both P<0.0001) but was lower than that in Group3 (324±93.7 pg/mL) (P=0.002). NO level in group 1 (27±1.4 μmol/L) was significantly higher than that in group 2 (19.8±2.8 μmol/L) and group 4 (16.9±1.6μmol/L) but was lower than that in Group 3 (39±3.6 μmol/L)(for all three P<0.0001). A strong correlation was observed between ADM and NO levels (r=0.827, P<0.0001).CONCLUSION: Adrenomedullin and NO levels were high in both non-cirrhotic and cirrhotic portal hypertension and were closely correlated, Adrenomedullin and NO levels increased proportionally with the severity of cirrhosis, and were significantly higher than those in patients with NCPH.Portal hypertension plays an important role in the increase of ADM and NO. Parenchymal damage in cirrhosis may contribute to the increase in these parameters.	V Tahan E Avsar C Karaca E Uslu F Eren S Aydin H Uzun HO Hamzaoglu F Besisik C Kalayci A Okten N Tozun	2003	World Journal of Gastroenterology2003，9，10：	5
	2	Balanced operation of three-phase induction motor with asymmetrical stator windings connected to single-phase supply system 显示文摘	TOZUNE A	1991	lEE Proceedings B: Electric Power Applications1991，138，4：	1
	3	Prevalence of dysmenor- rhea and its effect on quality of life among a group of female university students显示文摘	Unsal A Ayranci U Tozun M	2010	Ups J Med Sci2010，115，2：	1
	4	Balanced operation of three-phase induction motor with asymmetrical stator windings connected to single-phase supply system 显示文摘	Tozune A DEng	1991	IEE PROCEEDINGS-B1991，138，4：	1
	5	Prevalence of urinary incontinence among women and its impact on quality of life in a semiruraX area of Western Turkey 显示文摘	Tozun M Ayranci U Unsal A	2009	Gynecol Obstet Invest2009，67，4：	1
	6	Prevalence of dysmenor-rhea and its effect on quality of life among a group of female u- niversity students 显示文摘	Unsal A Ayranci U Tozun M	2010	Ups J Med Sci2010，115，2：	1
	7	Balanced operation of three-phase induction motor with asymmetrical stator windings connected to single-phase supply system显示文摘	TOZUNE A DENG	1991	IEE PROCEEDINGS-B1991，138，4：	1
	8	Balanced operation of three-phase induction motor with asymmetrical stator windings connected to single-phase supply system显示文摘	Tozune A D	1991	IEE Proceeding Part B1991，138，4：	1
	9	Balanced operation of three-phase induction motor with asymmetrical stator windings connected to single-phase supply system显示文摘	A Tozune DEng	1991	IEE PROCEEDINGS-B1991，138，4：	1
	10	Headache and its effects on health-related quality of life among adults 显示文摘	Arslantas D Tozun M Unsal A	2013	TurkNeurosurg2013，23，4：	1
	11	Balanced operation of three-phase induction motor with asymmetrical stator windings connected to single-phase supply system显示文摘	DEng A Tozune	1991	IEE PROCEEDINGS-B1991，138，4：	1
	12	Balanced operation of three - phase induction motor with asymmetrical stator windings connected to single - phase supply system显示文摘	TOZUNE A	1991	IEE PROCEEDINGS - B1991，138，4：	1
	13	Balanced operation of three-phase induetion motor with asymmetrical stator windings connected to single-phase supply system显示文摘	Tozune A Eng D	1991	IEE Proc-B1991，138，4：	1
	14	Prevalence of dysmenorrheal and its effect on quality of life among a group of female university students显示文摘	Unsal A Ayranci U Tozun M	2010	Ups J Mecl Sci2010，115，2：	1

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