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| 1 | Endoscopic ultrasonography-guided fine needle aspiration:Relatively low sensitivity in the endosonographer population显示文摘AIM:To assess the characteristics and quality of endoscopic ultrasonography-guided fine needle aspiration(EUS-FNA) in a large panel of endosonographers.METHODS:A survey was conducted during the 13th annual live course of endoscopic ultrasonography(EUS) held in Amsterdam,Netherlands.A 2-page questionnaire was developed for the study.Content validity of the questionnaire was determined based on input by experts in the field and a review of the relevant literature.It contained 30 questions that pertained to demographics and the current practice for EUS-FNA of responders,including sampling technique,sample processing,cytopathological diagnosis and sensitivity of EUS-FNA for the diagnosis of solid mass lesions.One hundred and sixty-one endosonographers who attended the course were asked to answer the survey.This allowed assessing the current practice of EUS-FNA as well as the self-reported sensitivity of EUS-FNA for the diagnosis of solid mass lesions.We also examined which factors were associated with a self-reported sensitivity of EUS-FNA for the diagnosis of solid mass lesions > 80%.RESULTS:Completed surveys were collected from 92(57.1%) of 161 endosonographers who attended the conference.The endosonographers had been practicing endoscopy and EUS for 12.5 ± 7.8 years and 4.8 ± 4.1 years,respectively;one third of them worked in a hospital with an annual caseload > 100 EUS-FNA.Endoscopy practices were located in 29 countries,including 13 countries in Western Europe that totaled 75.3% of the responses.Only one third of endosonographers reported a sensitivity for the diagnosis of solid mass lesions > 80%(interquartile range of sensitivities,25.0%-75.0%).Factors independently associated with a sensitivity > 80% were(1) > 7 needle passes for pancreatic lesions or rapid on-site cytopathological evaluation(ROSE)(P < 0.0001),(2) a high annual hospital caseload(P = 0.024) and(3) routine isolation of microcores from EUS-FNA samples(P = 0.042).ROSE was routinely available to 27.9% of respondents.For lymph nodes and pancreatic masses,a maximum of three needle passes was performed by approximately two thirds of those who did not have ROSE.Microcores were routinely harvested from EUS-FNA samples by approximately one third(37.2%) of survey respondents.CONCLUSION:EUS-FNA sensitivity was considerably lower than reported in the literature.Low EUS-FNA sensitivity was associated with unavailability of ROSE,few needle passes,absence of microcore isolation and low hospital caseload. | Jean-Marc Dumonceau Thibaud Koessler Jeanin E van Hooft Paul Fockens | 2012 | World Journal of Gastroenterology2012，18，19： | 7 |
| 2 | Long-term surgical results and patient satisfaction with male pseudohermaphroditism or true hermaphroditism:a cohort of 63 patients显示文摘 | Nihoul-Fe ke te C Thibaud E Lortat-Jacob S | 2006 | J Urol2006，175，5： | 1 |
| 3 | High performance method for o-methylation of phenol with dimethyl carbonate显示文摘 | OUK S THIBAUD S BORREDON E GARS P L | 2003 | Appl Catal A2003，241，12： | 1 |
| 4 | O-methylation of phenolic compounds with dimethyl carbonate under solid/liquid phase transfer system显示文摘 | OUK S THIBAUD S BORREDON E GARS P L LECOMTE L | 2002 | Tetrahedron Lett2002，43，14： | 1 |
| 5 | Long-term surgical results and patient satisfaction with male pseudohermaphroditism or true hermaphroditism: a cohort of 63 patients显示文摘 | NIHOUL-FEkETE C THIBAUD E LORTAT-JACOB S | 2006 | J Urol2006，175，5： | 1 |
| 6 | Factors affecting gonadal function after bone marrow transplantation during childhood显示文摘 | Couto-Silva AC Trivin C Thibaud E | 2001 | Bone Marrow Transplant2001，17，： | 1 |
| 7 | Follow up of pre- cocious pseudopuberty associated with isolated ovarian follicular - cysts显示文摘 | Rodriguez Macias KA Thibaud E Houang M | 2009 | Arch Dis Child2009，81，1： | 1 |
| 8 | Ovarian function after bone marrow transplantation during childhood 显示文摘 | Thibaud E Rodriguez - Macias K Trivin C | 1998 | Bone Marrow Transplant1998，21，3： | 1 |
| 9 | Ovarian function after bone marrow transplantation during childhood显示文摘 | Thibaud E Rodriguez-Macias K Trivin C | 1998 | Bone Marrow Transplant1998，21，： | 1 |
| 10 | Ovarian function after bone marrow transplantation during childhood显示文摘 | Thibaud E Rodriguez-Macias K Trivin C | 1998 | Bone Marrow Transplant1998，21，3： | 1 |
| 11 | Rokitansky syndrome: clinical experience and results of sigmoid vaginoplasty in 23 young girls 显示文摘 | Khen-Dunlop N Lortat-Jacob S Thibaud E | 2007 | J Urol2007，177，3： | 1 |
| 12 | Ovarian function after bone marrow transplantation during childhood显示文摘 | Thibaud E | 2003 | Bone Marrow Transplant2003，21，： | 1 |
| 13 | Ovarian functionafter bone marrow transplantation during childhood 显示文摘 | Thibaud E Rodriguez-Macias K Trivin C | 1998 | BoneMarrow Transplant1998，21，3： | 1 |
| 14 | Rokitansky syndrome:clinical experience and results of sigrmoid vaginoplasty in 23 young girls显示文摘 | Lortat-Jacob S Thibaud E | 2007 | J Urol2007，177，3： | 1 |
| 15 | Journal of pediatric and adolescent显示文摘 | Duflos Cohade C Amandruz M Thibaud E | | 0，，01： | 1 |
| 16 | Long-term outcome of patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency 显示文摘 | Bachelot A Plu B G Thibaud E | 2007 | Horm Res2007，67，6： | 1 |
| 17 | Rokitansky syndrome:clinical experience and results of sigmoidvaginoplasty in 23 young girls显示文摘 | KHEN-DUNLOP N LORTAT-JACOB S THIBAUD E | 2007 | J Urol2007，177，3： | 1 |
| 18 | Follow up of precocious pseudopubertyas sociated with isolated ovarian follicular cysts显示文摘 | Rodriguez Macias KA Thibaud E Houang M | 1999 | Arch Dis Child1999，81，1： | 1 |
| 19 | Long-term surgical results and patient satisfaction with male pseudohermaphroditism or true hermaphroditism:a cohort of 63 patients显示文摘 | Nihoul-Fekete C Thibaud E Lortat-Jacob S | 2006 | J Urol2006，175，5： | 1 |
| 20 | Breast Disea- ses in Adolescents显示文摘 | Duflos C Plu-Bureau G Thibaud E | 2012 | Endocr Dev2012，22，： | 1 |
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