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| 1 | 初级保健中原发性醛固酮增多症的患病率和临床表现显示文摘原发性醛固酮增多症(primaryaldosteronism,PA)是一种异质性疾病,以高血压和相对自主于肾素血管紧张素系统产生过量醛固酮为特征。与心血管病风险相似的原发性高血压患者相比,PA患者发生心脑血管并发症的风险以及代谢综合征患病率增加,提示正确诊断PA的重要性。 | Monticone S Burrello J Tizzani D Bertello C Viola A Buffolo F Gabetti L Mengozzi G Williams TA Rabbia F Veglio F Mulatero P 练桂丽 叶鹏 | 2017 | 中华高血压杂志2017，25，5： | 58 |
| 2 | Plasmonics for solid-state lighting: enhanced excitation and directional emission of highly efficient light sources显示文摘Light sources based on reliable and energy-efficient light-emitting diodes (LEDs) are instrumental in the development of solid-statelighting (SSL). Most research efforts in SSL have focused on improving both the intrinsic quantum efficiency (QE) and the stability oflight emitters. For this reason, it is broadly accepted that with the advent of highly efficient (QE close to 1) and stable emitters, thefundamental research phase of SSL is coming to an end. In this study, we demonstrate a very large improvement in SSL emission (above70-fold directional enhancement for p-polarized emission and 60-fold enhancement for unpolarized emission) using nanophotonicstructures. This is attained by coupling emitters with very high QE to collective plasmonic resonances in periodic arrays of aluminumnanoantennas. Our results open a new path for fundamental and applied research in SSL in which plasmonic nanostructures are able tomold the spectral and angular distribution of the emission with unprecedented precision. | Gabriel Lozano Davy J Louwers Said RK Rodrı´guez Shunsuke Murai Olaf TA Jansen Marc A Verschuuren Jaime Gomez Rivas | 2013 | Light(Science & Applications)2013，2，1： | 8 |
| 3 | 脑缺血后N-myc下游调控基因2保护血脑屏障完整性显示文摘脑缺血后血脑屏障(BBB)的破坏与外周细胞向脑内浸润、病孔损形成与进展、以及临床病程恶化密切相关。目前BBB完整性的调控机制,尤其是在永久性缺血后的调控机制尚未明确。本研究使用小鼠永久性脑缺血模型进行相关研究,结果显示,星形胶质细胞N-myc下游调控基因2(NDRG2)可能是缺血性脑卒中后BBB通透性的调控分子,该分子与分化和应激相关。免疫组化显示,在永久性大脑中动脉闭塞(MCAO)后,NDRG2在星形胶质细胞中的表达显著增加。敲除NDRG2基因,脑梗死体积增加,免疫细胞在缺血同侧大脑半球积聚增加。MCAO后,NDRG2基因敲除小鼠缺血侧皮质的缺血灶内及灶周血管周围区域内的血清蛋白(包括纤维蛋白原和免疫球蛋白)的外渗增强此之,MCAO后NDRG2基因敲除小鼠体内基质金属蛋白酶(MMPs)的表达也显著增加。在细胞培养中,NDRG2-/-星形胶质细胞中MMP-3的表达和分泌增加,这种增加可被腺病毒介导的NDRG2再表达所逆转。综上所述,脑缺血后,星形胶质细胞内的NDRG2可能通过调节MMP的表达,而在BBB通透性的调节和免疫细胞浸润中起到重要作用。 | Takarada-Iemata M Yoshikawa A Ta HM Okitani N Nishiuchi T Aida Y Kamide T Hattori T Ishii H Tamatani T Le TM Roboon J Kitao Y Matsuyama T Nakada M Hori O 聂昊 | 2018 | 神经损伤与功能重建2018，13，4： | 4 |
| 4 | 乙琥胺、丙戊酸和拉莫三嗪治疗儿童失神癫痫的临床试验显示文摘背景:儿童失神癫痫(CAE)是最常见的儿童癫痫综合征,一般常用乙琥胺、丙戊酸或拉莫三嗪治疗,但最有效和耐受性好的首选治疗尚未确定。方法:该研究是美国多中心、随机、双盲、对照临床试验,旨在比较乙琥胺、丙戊酸和拉莫三嗪治疗新诊断CAE儿童的疗效、耐受性和对神经心理的影响。 | Glauser TA Cnaan A Shinnar S 李新 王纪佐 | 2011 | 中华神经科杂志2011，44，8： | 3 |
| 5 | Integrated backscatter during harmonic and fundamental frequency imaging-effect of depth, mechanical index, and tissue anisotropy: implications for myocardial tissue characterization显示文摘 | Beaver TA Jansujwicz A Arbuckle BE | 2003 | Echocardiography2003，20，： | 2 |
| 6 | CagA status of Helicobacter pylori infection and p53 gene mutations in gastric adenocarcinoma显示文摘 | Shibata A Parsonnet J Longacre TA | 2002 | Carcinogenesis2002，23，3： | 2 |
| 7 | Association of HLA class Ⅰ antigens and HLA class Ⅱ alleles with vitiligo in a Turkish population显示文摘 | Ta tan HB Akar A Orkanoglu FE | 2004 | Pigment Cell Res2004，17，2： | 1 |
| 8 | Cholangiocarcinoma: a spectrum of intrahepatic, perihilar, and distal tumors 显示文摘 | Nakeeb A Pitt HA Sohn TA | 1996 | Ann Surg1996，224，46： | 1 |
| 9 | Anterior instrumentation in the managerment of thoracolumbar burst fractures 显示文摘 | Ghanayem A J Zdeblick TA | 1997 | Clin Orthop1997，，335： | 1 |
| 10 | Peritoneal fluid and sex steroids in the preovulatory period in mild endometriosis显示文摘 | Templeton A | 1991 | Br J Obstet Gynecol1991，98，2： | 1 |
| 11 | Identification of genes in an extraintestinal isolate of Escherichia coli with increased expression after exposure to human urine 显示文摘 | Russo TA Carlino UB Mong A | 1999 | Infect Immun1999，67，10： | 1 |
| 12 | ICF core sets:how to specify impairment and function in systemic Lupus erythematosus显示文摘 | Aringer M Stamm TA Pisetsky DS Yarboro CH Cieza A Smolen JS | 2006 | Lupus2006，15，： | 1 |
| 13 | Expression of the transcription factors snail,slug,and twist and their clinical significance in human breast cancer显示文摘 | Martin TA Goyal A Watkins G | 2005 | Ann Surg Oncol2005，12，6： | 1 |
| 14 | Relation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbations 显示文摘 | Bhowmik A Seemungal TA Sapsford R J | 2000 | Thorax2000，55，2： | 1 |
| 15 | Phase II Study of Pemetrexed and Carboplatin Plus Bevacizumab With Maintenance Pemetrexed and Bevacizumab As First - line Therapy for Non- squamous Non - Small~ Lung Cancer显示文摘 | Patel JD Hensing TA Rademaker A | 2009 | Clin Oncol2009，27，20： | 1 |
| 16 | Species variation in the fixation and transfer of nitrogen from legume to association grass显示文摘 | TA T C FARIS M A | 1987 | Plant and Soil1987，98，： | 1 |
| 17 | Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease 显示文摘 | DONALDSON GC SEEMUNGAL TA BHOWMIK A | 2002 | Thorax2002，57，： | 1 |
| 18 | Longitudinal survey of carbapenem resistance and re-sistance mechanisms in Enterobacteriaceae and non-fermenters from the USA in 2007?2009显示文摘 | Daviesl TA Marie Queenan A Morrow BJ | 2011 | J Anti-microb Chemother2011，66，10： | 1 |
| 19 | Sertraline versusother antidepressive agents for depression 显示文摘 | Cipriani A La Ferla T Furukawa TA | 2010 | Cochrane Database Syst Rev2010，14，00： | 1 |
| 20 | Ownership structure and risk in publicly held and privately owned banks 显示文摘 | Barry TA Lepetit L Tarazi A | 2011 | Journal of Banking and Finance2011，35，5： | 1 |
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