|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Role of bile acids in the regulation of the metabolic pathways显示文摘Recent studies have revealed that bile acids(BAs)are not only facilitators of dietary lipid absorption but also important signaling molecules exerting multiple physiological functions.Some major signaling pathways involving the nuclear BAs receptor farnesoid X receptor and the G protein-coupled BAs receptor TGR5/M-BAR have been identified to be the targets of BAs.BAs regulate their own homeostasis via signaling pathways.BAs also affect diverse metabolic pathways including glucose metabolism,lipid metabolism and energy expenditure.This paper suggests the mechanism of controlling metabolism via BA signaling and demonstrates that BA signaling is an attractive therapeutic target of the metabolic syndrome. | Hiroki Taoka Yoko Yokoyama Kohkichi Morimoto Naho Kitamura Tatsuya Tanigaki Yoko Takashina Kazuo Tsubota Mitsuhiro Watanabe | 2016 | World Journal of Diabetes2016，7，13： | 11 |
| 2 | Ectopic gastrointestinal variceal bleeding with portal hypertension显示文摘Massive gastrointestinal bleeding from gastrointestinal varices is one of the most serious complications in patients with portal hypertension. However, if no bleeding point can be detected by endoscopy in the predilection sites of gastrointestinal varices, such as the esophagus and stomach, ectopic gastrointestinal variceal bleeding should be considered as a differential diagnosis. Herein, we report a case of ectopic ileal variceal bleeding in a 57-year-old woman, which was successfully diagnosed by multi-detector row CT(MDCT) and angiography and treated by segmental ileum resection. To date, there have been no consensus for the treatment of ectopic ileal variceal bleeding. This review was designed to clarify the clinical characteristics of patients with ectopic ileal variceal and discuss possible treatment strategies. From the PubMed database and our own database, we reviewed 21 consecutive cases of ileal variceal bleeding diagnosed from 1982 to 2017. MDCT and angiography is useful for the rapid examination and surgical resection of an affected lesion and is a safe and effective treatment strategy to avoid further bleeding. | Keita Minowa Shuhei Komatsu Kenichiro Takashina Sachie Tanaka Tatsuya Kumano Kenichiro Imura Katsumi Shimomura Jun Ikeda Fumihiro Taniguchi Yasuo Ueshima Tecchuu Lee Eito Ikeda Eigo Otsuji Yasuhiro Shioaki | 2017 | World Journal of Gastrointestinal Surgery2017，9，12： | 4 |
| 3 | Modified quadratic discriminant functions and the application to Chinese character recognition 显示文摘 | K Takashina | 1987 | IEEE Trans1987，9，1： | 1 |
| 4 | Modified quadratic discriminant functions and the application to Chinese character recognition 显示文摘 | KIMURA F TAKASHINA K TSURUOKA S | 1987 | IEEE Trans on Pattern Analysis and Machine Intelligence1987，9，1： | 1 |
| 5 | Palmar dermatoglyphics in heart dis ease显示文摘 | Takashina T Nakamura K | 1973 | Singapore Med J1973，14，3： | 1 |
| 6 | Impact of CYP3A5 and ABCB1gene polymorphisms on fentanyl pharmacokinetics and clinical responsed in cancer patients undergoing conversion to a transdermal system显示文摘 | Takashina Y Naito T Mino Y | 2012 | Durg Metab Pharmacokinet2012，27，4： | 1 |
| 7 | Validated LC coupled to ESI-MS -MS analysis for fentanyl in human plasma and LIV analysis in applied reservoir transdermal patches using a simple and rapid proce- dure显示文摘 | Takashina Y Naito T Mino Y | 2009 | J Clin Pharm Ther2009，34，5： | 1 |
| 8 | The effects of propofol, isoflurane, and sevoflurane on oxygenation and shunt fraction during one-lung ventilation显示文摘 | Abe K Shimizu T Takashina M | 1998 | Anesth Analg1998，87，5： | 1 |
| 9 | The possibility of dow el removal by pulsed Nd: YAG laser irradiation显示文摘 | Takashina M Ebihara A Sunakawa M | 2002 | Laser Surg Med2002，31，4： | 1 |
| 10 | Modified Quadratic Discriminant Functions and Its Application to Chinese Character Recognition 显示文摘 | Kimura F Takashina K Tsuruoka S | 1987 | IEEE Trans on Pattern Analysis and Machine Intelligence1987，9，1： | 1 |
| 11 | Ship turning trajectory in regular waves 显示文摘 | HIRANO M TAKASHINA J TAKAISHI Y | 1980 | West Japan So- ciety of Naval Architects1980，60，： | 1 |
| 12 | Clinicopathological features of small T1 colorectal cancers显示文摘BACKGROUND Although small colorectal neoplasms(<10 mm)are often easily resected endoscopically and are considered to have less malignant potential compared with large neoplasms(≥10 mm),some are invasive to the submucosa.AIM To clarify the clinicopathological features of small T1 colorectal cancers.METHODS Of 32025 colorectal lesions between April 2001 and March 2018,a total of 1152 T1 colorectal cancers resected endoscopically or surgically were included in this study and were divided into two groups by tumor size:a small group(<10 mm)and a large group(≥10 mm).We compared clinicopathological factors including lymph node metastasis(LNM)between the two groups.RESULTS The incidence of small T1 cancers was 10.1%(116/1152).The percentage of initial endoscopic treatment in small group was significantly higher than in large group(<10 mm 74.1%vs≥10 mm 60.2%,P<0.01).In the surgical resection cohort(n=798),the rate of LNM did not significantly differ between the two groups(small 12.3%vs large 10.9%,P=0.70).In addition,there were also no significant differences between the two groups in pathological factors such as histological grade,vascular invasion,or lymphatic invasion.CONCLUSION Because there was no significant difference in the rate of LNM between small and large T1 colorectal cancers,the requirement for additional surgical resection should be determined according to pathological findings,regardless of tumor size. | Yuki Takashina Shin-Ei Kudo Katsuro Ichimasa Yuta Kouyama Kenichi Mochizuki Yoshika Akimoto Yasuharu Maeda Yuichi Mori Masashi Misawa Noriyuki Ogata Toyoki Kudo Tomokazu Hisayuki Takemasa Hayashi Kunihiko Wakamura Naruhiko Sawada Toshiyuki Baba Fumio Ishida Kazunori Yokoyama Mitsuru Daita Tetsuo Nemoto Hideyuki Miyachi | 2021 | World Journal of Clinical Cases2021，9，33： | 1 |
| 13 | Effects of salts on limestone dissolution rate in wet limestone flue gas desulfurization 显示文摘 | UKAWA N TAKASHINA T OSHIMA M | 1993 | Environment Progress1993，12，4： | 1 |
| 14 | Application of a newly designed right-sided,double-lumen endobronchial tube in patients with a very short right mainstem bronchus显示文摘 | Hagihira S Takashina M Mashimo T | 2008 | Anesthesiology2008，109，3： | 1 |
| 15 | Practical issues in bispectral analysis of electroencephalographic signals 显示文摘 | HAGIHIRA S TAKASHINA M MOR1 T | 2001 | Anesth Analg2001，93，4： | 1 |
| 16 | Heterogeneity of hepatic parenchyma enhancement on computed tomography during arterial portography:quantitative analysis of correlation with severity of hepatic fibrosis显示文摘 | Taura T Nakamura K Takashina S | 2001 | J Hepatoi Res2001，20，2： | 1 |
| 17 | Highly 3-selective mannosyl-ation towards man 1-4 GlcNNAc synthesis: TMSB (C6F5)4 as a Lewis acid/Cation trap catalyst 显示文摘 | Tanaka S Takashina M Tokimoto H | 2005 | Synlett2005，15，： | 1 |
| 18 | Effects of particle size distribution on limestone dissolution in wet flue gas desulfurization applications显示文摘 | Ukawa N Takashina T Shinoda N | 1993 | Environmental Progress1993，12，1： | 1 |
| 19 | Surface friction of hydrogels with well defined polyelectrolyte brushes 显示文摘 | OHSEDO Y TAKASHINA R GONG J | 2004 | Langmuir2004，20，16： | 1 |
| 20 | MKC - 231, a choline uptake enhancer: Mode of aetion of MKC-231 in the enhancement o high-affinity choline uptake显示文摘 | Takashina K | 2008 | J Neural Transm2008，115，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员