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| 1 | Helicobacter pylori associated chronic gastritis,clinical syndromes,precancerous lesions,and pathogenesis of gastric cancer development显示文摘Helicobacter pylori(H.pylori)infection is well known to be associated with the development of precancerous lesions such as chronic atrophic gastritis(AG),or gastric intestinal metaplasia(GIM),and cancer.Various molecular alterations are identified not only in gastric cancer(GC)but also in precancerous lesions.H.pylori treatment seems to improve AG and GIM,but still remains controversial.In contrast,many studies,including meta-analysis,show that H.pylori eradication reduces GC.Molecular markers detected by genetic and epigenetic alterations related to carcinogenesis reverse following H.pylori eradication.This indicates that these changes may be an important factor in the identification of high risk patients for cancer development.Patients who underwent endoscopic treatment of GC are at high risk for development of metachronous GC.A randomized controlled trial from Japan concluded that prophylactic eradication of H.pylori after endoscopic resection should be used to prevent the development of metachronous GC,but recent retrospective studies did not show the tendency.Patients with precancerous lesions(molecular alterations)that do not reverse after H.pylori treatment,represent the'point of no return'and may be at high risk for the development of GC.Therefore,earlier H.pylori eradication should be considered for preventing GC development prior to the appearance of precancerous lesions. | Jiro Watari Nancy Chen Peter S Amenta Hirokazu Fukui Tadayuki Oshima Toshihiko Tomita Hiroto Miwa Kheng-Jim Lim Kiron M Das | 2014 | World Journal of Gastroenterology2014，20，18： | 60 |
| 2 | Phenol oxidation kinetics in supercritical water 显示文摘 | Oshima Y Hori K Toda M | 1998 | Journal of super-critical fluids1998，13，2： | 1 |
| 3 | Effects of modified ultrafiltration on coagulation factors in pediatric cardiac surgery显示文摘 | Yamaguchi M Oshima Y | 2002 | Surg Today2002，32，3： | 1 |
| 4 | Bacterial flora in the gastrointestine of freshwater fishes in the river显示文摘 | SUGITA H OSHIMA K TAMURA M | 1983 | Bull Japan Soc Sci Fish1983，49，9： | 1 |
| 5 | Usefulness of virtual histology intravascular ultrasound to predict distal embolization for ST- segment elevation myocardial infarction 显示文摘 | Kawaguchi R Oshima S Jingu M | 2007 | J Am Coll Cardiol2007，50，17： | 1 |
| 6 | 显示文摘 | Oshima H Nakamura M Miyano K | 2001 | Phys Rev B2001，63，75： | 1 |
| 7 | Structural Properties of GaN Grown on LiGaO2 by PLD显示文摘 | Takahashi H Fujioka H Ohta J Oshima M Kimura M | 2003 | Journal of Crystal Growth2003，259，12： | 1 |
| 8 | Chemoprevention of intestinal polyposis in the Apcdelta716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor显示文摘 | Oshima M Murai N Karqman S | 2001 | Cancer Res2001，61，4： | 1 |
| 9 | Observation and digital control of the molten pool in pulsed MIG welding显示文摘 | OSHIMA K MORITA M | 1988 | Welding International1988，2，3： | 1 |
| 10 | Cyelooxygenase 2-and prostaglandin E (2) receptor EP (2)-dependent angiogenesis in Apc (Delta716) mouse intestinal polyps 显示文摘 | SENO H OSHIMA M ISHIKAWA | 2002 | Cancer Res2002，62，2： | 1 |
| 11 | Molecular characterization of long direct repeat(LDR) sequences expressing a stable mRNA encoding for a 35-amino-acid cell-killing peptide and a cisencoded small antisense RNA in Escherichia coli显示文摘 | Kawano M Oshima T Kasai H | 2002 | Mol Microbiol2002，45，2： | 1 |
| 12 | Microemulsions in supercritical CO2 utilizing the polyethyleneglycol dialkylglycerol and their use for the solubilization of hydrophiles 显示文摘 | Sawada K Oshima M Sugimito M | 2005 | Dyes and Pigments2005，65，1： | 1 |
| 13 | Survey of surgical indications and results of primary pars plana vitrectomy for rhegmatogenous retinal detachments显示文摘 | Oshima Y Emi K Motokura M Yamanishi S | | 0，，02： | 1 |
| 14 | Microemulsions in supercritical CO2 utilizing the polyethyleneglycol dialkylglycerol and their use for the solubilization of hydrophiles 显示文摘 | Sawada K Oshima M Sugimito M | 2005 | Dyes and Pigments2005，65，1： | 1 |
| 15 | Lung radiofrequency ablation with and without bronchial occlusion: experimental study in porcine lungs显示文摘 | Oshima F Yamakado K Akeboshi M | 2004 | J Vasc Interv Radiol2004，15，12： | 1 |
| 16 | Development of an oral drug delivery systemtargeting immune-regulating cells in experimentalinflammatory bowel disease: a new therapeutic strategy显示文摘 | Nakase H Okazaki K Tabata Y Uose S Ohana M Uchida K Matsushima Y Kawanami C Oshima C IkadaY Chiba T | 2000 | Journal of Pharmacology and ExperimentalTherapeutics2000，292，1： | 1 |
| 17 | Renal response to L-arginine in salt-sensitive patients with essential hypertension 显示文摘 | Higashi Y Oshima T Watanabe M | 1996 | Hypertension1996，27，3： | 1 |
| 18 | The inflammatory network in the gastrointestinal tumor microenvironment:lessons from mouse models显示文摘 | Oshima H Oshima M | | 0，，02： | 1 |
| 19 | The quality of life among persons with severe mental illness enrolled in an asser- tive community treatment program in Japan: 1 year follow up and analyses显示文摘 | Horiuchi K Nisihio M Oshima I | 2006 | Clin Pract Epidemiol Ment Health2006，2，： | 1 |
| 20 | Magnitude and role of wall shear stress on cerebral aneurysm computational fluid dynamic study of 20 middle cerebral artery Aneurysms显示文摘 | Shojima M Oshima M | 2004 | Stroke2004，35，： | 1 |
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