| 1 | SARS-CoV-2-specific T cells in infection and vaccination显示文摘During viral infections,antibodies and T cells act together to prevent pathogen spread and remove virus-infected cells.Virusspecific adaptive immunity can,however,also trigger pathological processes characterized by localized or systemic inflammatory events.The protective and/or pathological role of virus-specific T cells in SARS-CoV-2 infection has been the focus of many studies in COVID-19 patients and in vaccinated individuals.Here,we review the works that have elucidated the function of SARS-CoV-2-specific T cells in patients and in vaccinated individuals.Understanding whether SARS-CoV-2-specific T cells are more linked to protection or pathogenesis is pivotal to define future therapeutic and prophylactic strategies to manage the current pandemic. | Antonio Bertoletti Nina Le Bert Martin Qui Anthony T.Tan | 2021 | Cellular & Molecular Immunology2021，18，10： | 3 |
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