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2篇 您的检索式:作者名="T.Marimuthu"
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1Effect of Deposition Potential on Synthesis, Structural,Morphological and Photoconductivity Response of Cu2O Thin Films by Electrodeposition Technique显示文摘The present work describes the effect of deposition potentials on structural,morphological,optical,electrical and photoconductivity responses of cuprous oxide(Cu2O)thin films deposited on fluorine-doped tin oxide glass substrate by employing electrodeposition technique.X-ray diffraction patterns reveal that the deposited films have a cubic structure grown along the preferential(111)growth orientation and crystallinity of the film deposited at.0.4 V is improved compared to the films deposited at.0.2,.0.3 and.0.5 V.Scanning electron microscopy displays that surface morphology of Cu2O film has a well-defined three-sided pyramid-shaped grains which are uniformly distributed over the surface of the substrates and are significantly changed as a function of deposition potential.Raman and photoluminescence spectra manifest that the film deposited at.0.4 V has a good crystal quality with higher acceptor concentration compared to other films.UV–visible analysis illustrates that the absorption of Cu2O thin film deposited at.0.4 V is notably higher compared to other films and the band gap of Cu2O thin films decreases from 2.1 to 2.04 eV with an increase in deposition potential from.0.2 to.0.5 V.The frequency–temperature dependence of impedance analysis shows that the film deposited at.0.4 V has a high conductivity.I– V measurements elucidate that the film deposited at.0.4 V exhibits a good photoconductivity response compared to films deposited in other deposition potentials.K.P.Ganesan N.Anandhan T.Marimuthu R.Panneerselvam A.Amali Roselin 2019Acta Metallurgica Sinica(English Letters)2019,32,9:2
2Structural Basis for Complementary and Alternative Medicine:Phytochemical Interaction with Non-Structural Protein 2 Protease-A Reverse Engineering Strategy显示文摘Objective:To understand the druggability of the bioactive compounds from traditional herbal formulations 'Nilavembu Kudineer' and 'Swasthya Raksha Amruta Peya' to heal chikungunya virus(CHIKV)infection.Methods:The efficiency of twenty novel chemical entities from 'Nilavembu Kudineer' and 'Swasthya Raksha Amruta Peya' to inhibit CHIKV infection in silico were evaluated.Ligands were prepared using Ligprep module of Schrodinger.Active site was identified using SiteMap program.Grid box was generated using receptor grid generation wizard.Molecular docking was carried out using Grid Based Ligand Docking with Energetics(GLIDE) program.Results:Molecular docking studies showed that among twenty compounds,andrographoside,deoxyandrographoside,neoandrographoiide,14-deoxy-11-oxoandrographolide,butoxone and oleanolic acid showed GLIDE extra precision(XP) score of-9.10,-8.72,-8.25,-7.38,-7.28 and-7.01,respectively which were greater than or comparable with chloroquine(reference compound) XP score(-7.08)and were found to interact with the key residues GLU 1043,LYS 1045,GLY 1176,LEU 1203,HIS 1222 and LYS 1239 which were characteristic functional unit crucial for replication of CHIKV.Conclusion:The binding affinity and the binding mode of chemical entities taken from herbal formulations with non-structural protein 2protease were understood and our study provided a novel strategy in the development and design of drugs for CHIKV infection.G.Koushik Kumar G.Prasanna T.Marimuthu N.T.Saraswathi 2015Chinese Journal of Integrative Medicine2015,21,6:0
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