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| 1 | 芋病毒病田间调查及毒氟磷对芋病毒病的防治效果显示文摘对芋病毒病及类似病害症状进行调查,其症状表现主要分为羽状花叶、叶片向上卷曲并伴有黄化或花叶、脉间黄化、明亮褪绿黄斑、褪绿斑点(斑驳)及叶片皱缩和叶缘黄化。采用RT-PCR和PCR技术对随机采集的32份表现症状的鄂芋一号样品进行了芋花叶病毒(DsMV)和芋杆状病毒(TaBV)2种病毒的检测,检出率均为68.8%。同时,利用30%毒氟磷可湿性粉剂500倍液和1 000倍液对芋病毒病进行田间药效试验,第一次施药后10 d调查,毒氟磷可湿性粉剂500倍液和1 000倍液的防治效果分别为30.9%和24.9%;第二次施药后15 d调查,500倍液和1 000倍液防治效果分别为72.8%和59.4%。田间药剂试验结果表明,毒氟磷可湿性粉剂500倍液比1 000倍的防治效果好,从田间芋头长势可看出,毒氟磷对芋头生长有明显的促进作用。 | 王彦芬 Syeda Amber Kazmi 曲林宁 王国平 刘玉平 洪霓 | 2012 | 长江蔬菜2012，，16： | 7 |
| 2 | Kudo's pit pattern classification for colorectal neoplasms:A meta-analysis显示文摘AIM:To analyze the current available evidence of Kudo's pit pattern classification for diagnosing colorectal neoplasms.METHODS:A search was performed on Pubmed/Embase to identify studies reporting the outcomes of the pit pattern classification in colorectal polyps.Retrieved records were evaluated and selected by two independent investigators.The number of patients,polyps and diagnostic performance of Kudo’s pit pattern classification were retrieved from suitable studies.Pooled sensitivities and specificities were calculated using fixed or random effect models according to their heterogeneity.Publication bias was evaluated using funnel plot,Egger’s test,and Begg’s test.Sensitivity analysis was performed by omitting one study at a time and selecting a subgroup consisting of 11 magnifying chromoendoscopy studies.RESULTS:20 eligible studies were included in which a total of 5111 colorectal lesions in 3418 patients were identified for the differentiation of neoplastic and nonneoplastic polyps.Pit pattern classification in all the studies of mucosal patterns with magnification resulted in a pooled sensitivity of 89.0%(95%CI:85.2-91.9)and pooled specificity of 85.7%(95%CI:81.3-89.2)and the area under the SROC curve was 0.9354.There was significant publication bias(P=0.038 and 0.006 for sensitivity and specificity using Egger’s test,P=0.035and 0.139 for sensitivity and specificity using Begg’s test,respectively).No single study significantly affected the pooled result,and the magnifying chromoendoscopy subgroup yielded a sensitivity of 92.7%(95%CI:89.2-95.2)and specificity of 87.3%(95%CI:81.6-91.4).CONCLUSION:Kudo’s pit pattern classification is an accurate diagnostic method for the differentiation of neoplastic colorectal lesions.Publication bias is significant in the current available literature. | Ming Li Syed Mohsin Ali Syeda Umm-a-OmarahGilani Jing Liu Yan-Qing Li Xiu-Li Zuo | 2014 | World Journal of Gastroenterology2014，20，35： | 5 |
| 3 | 补充锌对小儿志贺氏菌痢患者免疫和炎症反应的影响显示文摘志贺氏菌痢,一种杆菌痢疾,是发展中国家儿童发病和死亡的一个主要原因,尤其是5岁以下儿童。在发展中国家,因频繁感染志贺氏菌而造成儿童的营养不良、生长迟缓,甚至引发危及生命的并发症。严重营养不良儿童患志贺氏菌痢的死亡率极高。 | Rubhana Raqib Swapan Kumar Roy Muhammad Jubayer Rahamn Tasnim Azim Syeda Shegufta Ameer Jobayer Chisti Jan Andersson 刘艳妮 王劲 | 2004 | 营养健康新观察2004，0，3： | 5 |
| 4 | Review of Mg alloy corrosion rates显示文摘A review of the literature confirmed that the intrinsic corrosion rate of high-purity Mg as measured by weight-loss is 0.3mm/y in a concentrated chloride solution.Atmospheric corrosion of Mg alloys has produced corrosion rates of Mg-Al alloys an order of magnitude lower than the intrinsic corrosion rate of Mg in a concentrated chloride solution of 0.3 mm/y.The only successful strategy to produce a Mg alloy with a corrosion rate in a concentrated chloride solution substantially less than the intrinsic corrosion rate as measured by weight loss of Mg of 0.3 mm/y has been to improve the protectiveness of the corrosion product film. | Andrej Atrens Zhiming Shi Syeda UMehreen Sean Johnston Guang-Ling Song Xianhua Chen Fusheng Pan | 2020 | Journal of Magnesium and Alloys2020，8，4： | 5 |
| 5 | Management of Acute Hypertensive Response in Patients with Intracerebral Hemorrhage显示文摘 | Syeda Alqadri Adnan Qureshi | 2012 | Current Atherosclerosis Reports2012，，4： | 4 |
| 6 | Mutant p53 promotes cell spreading and migration via ARHGAP44显示文摘The tumor suppressor p53 protein is either lost or mutated in about half of all human cancers.Loss of p53 function is well known to influence cell spreading,migration and invasion.While expression of mutant p53 is not equivalent to p53 loss,mutant p53 can acquire new functions to drive cell spreading and migration via different mechanisms.In our study,we found that mutant p53 significantly increased cell spreading and migration when comparing with p53-null cells.RNA-Seq analysis suggested that Rho GTPase activating protein 44(ARHGAP44) is a new target of mutant p53,which suppressed AKHGAP44 transcription.ARHGAP44 has GAP activity and catalyze GTP hydrolysis on Cdc42.Higher level of GTP-Cdc42 was correlated with increase expression of mutant p53 and reduced ARHGAP44.Importantly,wt-ARHGAP44 but not mutant ARHGAP44(R291A) suppressed mutant p53 mediated cell spreading and migration.Bioinformatics analysis indicated lower expression of ARHGAP44 in lung carcinoma compared with normal tissues,which was verified by RT-qPCR using specimens from patients.More interestingly,ARHGAP44 mRNA level was lower in tumors with mutant p53 than those with normal p53.Collectively,our results disclose a new mechanism by which mutant p53 stimulates cell spreading and migration. | Jinjin Xu Jian Jiao Wei Xu Lei Ji Dongjie Jiang Shaofang Xie Syeda Kubra Xiaotao Li Junjiang Fu Jianru Xiao Bianhong Zhang | 2017 | Science China(Life Sciences)2017，60，9： | 4 |
| 7 | 神经内镜与显微镜下经鼻蝶垂体腺瘤切除术效果对比分析显示文摘目的:探讨神经内镜与显微镜下经鼻蝶垂体腺瘤切除术的手术效果。方法:回顾分析2009年12月至2012年12月收治的263例患者的临床资料,其中105例行神经内镜垂体腺瘤切除术(内镜组),158例行显微镜下经鼻蝶入路垂体腺瘤切除术(显微镜组),对比分析两组患者手术时间、出血量、手术切除率、术后并发症发生率、术后住院时间等指标。结果:内镜组手术时间较显微镜组长[(78.7±34.55)min vs.(66.8±31.32)min](P=0.014);两组术中出血量差异无统计学意义[(60.6±32.35)ml vs.(55.1±24.63)ml](P=0.943);两组手术全切率差异亦无统计学意义(93.3%vs.92.4%)(P=0.7760);内镜组术后并发症发生率低于显微镜组(5.71%vs.13.29%),差异有统计学意义(P=0.0470)。内镜组术后住院时间较显微镜组短[(6.12±1.94)d vs.(7.13±1.57)d],差异有统计学意义(P=0.0166)。结论:神经内镜手术在肿瘤全切方面与显微镜组相当,但术后并发症发生率及术后住院时间具有明显优势,代表了经鼻蝶垂体腺瘤手术的发展方向。 | SYEDA QUDSIA AMJAD 刘青林 贾德泽 徐淑军 李新钢 李刚 | 2013 | 腹腔镜外科杂志2013，18，4： | 4 |
| 8 | Are serum leptin levels predicted by lipoproteins, vitamin D and body composition?显示文摘BACKGROUND Both obesity and vitamin D deficiency are important health issues in Pakistan.The connection between body composition, Vitamin D and leptin in young adults is important to be studied as body composition may affect bone health and therefore the possibility of osteoporosis in later life. Few studies have attempted to investigate the effect of body composition and leptin with vitamin D in adolescence.AIM To investigate the association of serum leptin with body composition, lipids and25-hydroxyvitamin D(25 OHD) in adults.METHODS This cross-sectional study was conducted on 167 apparently healthy adults.Demographics were recorded, bioelectrical impedance analysis was performed and clinical history noted. Serum leptin was measured using DIA source kit on ELISA and total 25 OHD was measured on ADVIA-Centaur; Siemens. Total cholesterol and high density lipoprotein cholesterol were quantified using Enzymatic Endpoint Method and Cholesterol Oxidase-Phenol Aminophenazone method respectively. Biochemical analysis was done in the Departments of Pathology and Laboratory Medicine and Biological and Biomedical Sciences, Aga Khan University Hospital Karachi Pakistan.RESULTS Median age of the group(n = 167) was 20 years(IQR 27-20); 55.7% were females.Majority(89.2%, n = 149) of the study group was 25 OHD deficient, 6%(n = 10)had insufficient serum 25 OHD levels and 4.8%(n = 8) had sufficient D levels.Females, had higher median leptin levels [2.71(IQR 4.76-1.66 ng/mL)] compared to their counterparts [1.3(3.60-0.54 ng/mL), P < 0.01]. Multiple regression analysis suggested that basal metabolic rate, muscle mass, body fat percent, bone mass and serum 25 OHD were the most contributing factors to serum leptin levels. Bone mass and serum 25 OHD in fact bore a negative correlation with leptin.CONCLUSION The results indicate that basal metabolic rate, muscle mass, body fat percent, bone mass and serum 25 OHD have an impact on serum leptin. Being a cross sectional study causal relationship between leptin and other variables could not be determined. | Aysha Habib Khan Syeda Sadia Fatima Ahmed Raheem Lena Jafri | 2019 | World Journal of Diabetes2019，10，4： | 4 |
| 9 | Malnutrition and liver disease in a developing country显示文摘Malnutrition is a highly prevalent and under recognized condition in developing countries of South Asia.The presence of malnutrition causes a severe impact on patients with liver cirrhosis.The etiology of cirrhosis differs in the South Asian region compared to the West,with hepatitis B and C still being the leading causes and the prevalence of nonalcoholic fatty liver disease increasing over time.Comorbid malnutrition worsens outcomes for cirrhosis patients.Urgent attention to address malnutrition is needed to improve patient outcomes.The etiology and pathophysiology of malnutrition in liver diseases is multifactorial,as reduction in liver function affects both macronutrients and micronutrients.A need for nutritional status assessment for liver disease patients exists in all parts of the world.There are many widely studied tools in use to perform a thorough nutritional assessment,of which some tools are low cost and do not require extensive training.These tools can be studied and evaluated for use in the resource limited setting of a country like Pakistan.Treatment guidelines for proper nutrition maintenance in chronic liver disease exist for all parts of the world,but the knowledge and practice of nutritional counseling in Pakistan is poor,both amongst patients and physicians.Emphasis on assessment for nutritional status at the initial visit with recording of vital signs is needed.Simultaneously,treating physicians need to be made aware of the misconceptions surrounding nutritional restrictions in cirrhosis so that patient education is done correctly based on proper scientific evidence. | Asra tus Saleha Siddiqui Om Parkash Syeda Amrah Hashmi | 2021 | World Journal of Gastroenterology2021，27，30： | 3 |
| 10 | UV Assisted Preliminary DNA Binding Studies and Single-crystal X-ray Structure of 4-{(4-Nitrophenyl-sulfonamido)methyl}cyclohexanecarboxylic Acid显示文摘A new sulfonamide, 4-{(4-nitrophenylsulfonamido)methyl}cyclohexanecarboxylic acid(C14H18N2O6S), has been synthesized by the reaction of tranexamic acid and 4-nitrobenzenesulfonyl chloride in basic medium at room temperature. The molecular structure was determined by FT-IR, NMR, elemental analysis and single-crystal X-ray technique. X-ray diffraction shows that the compound crystallizes in the monoclinic system, space group P21/c with a = 13.5980(7), b = 4.9877(2), c = 23.3878(13) ?, β = 93.254(3)o, Z = 4, V = 1583.67(14) ?3, μ = 0.237 mm-1, F(000) = 720, R = 0.0471 and w R = 0.1182. The molecules are related by inversion and paired into dimers via C–H···O interactions. The dimmers are interlinked due to strong N–H···O bonds, where O-atoms are of sulfonyl groups. The molecules are stabilized in the form of infinite two-dimensional network with base vectors [0 1 0] and [0 0 –1] in the plane(1 0 2). The existence of good intermolecular interactions suggests the biological importance of the synthesized molecule. The compound was screened for its interaction with FS-DNA using UV-visible spectroscopy. UV-visible spectroscopic results depict that the compound interacts with DNA by mixed binding mode intercalation along with hydrogen bonding. Negative values of ΔG(–23.34, –17.79 k J·mol-1) indicate spontaneity of the compound-DNA adduct formation. | MUHAMMAD Danish RABIA Ayub Butt MUHAMMAD Nawaz Tahir MUHAMMAD Ashfaq SYEDA Tahira Hafeez | 2017 | Chinese Journal of Structural Chemistry2017，36，5： | 3 |
| 11 | Effect of new berberine derivatives on colon cancer cells显示文摘自然的碱 berberine 最近被描述了为有希望的 anticancer 药。以便改进它的功效和 bioavailability,几衍生物被设计了并且综合并且发现了比铅混合物是甚至更多的有势力。在我们生产了的 berberine 衍生物的系列之中,五混合物被识别能重重地影响人的 HCT116 和 SW613-B3 冒号癌房间线的增长。显著地,这些活跃混合物展出导致 autophagy 的高荧光排放性质和能力。 | Luis Miguel Guaman Ortiz Anna Leta Croce Francesca Aredia Simone Sapienza Gaetano Fiorillo Tanjia Monir Syeda Franco Buzzetti Paolo Lombardi Anna Ivana Scovassi | 2015 | Acta Biochimica et Biophysica Sinica2015，47，10： | 2 |
| 12 | Characterization of hospital waste in Lahore, Pakistan显示文摘 | Sobia Munir Syeda Adila Batool Muhammad Nawaz Chaudhry | 2014 | Chinese Medical Journal2014，，9： | 2 |
| 13 | Conceivable Security Risks and Authentication Techniques for Smart Devices: A Comparative Evaluation of Security Practices显示文摘With the rapidly escalating use of smart devices and fraudulent transaction of users data from their devices, efficient and reliable techniques for authentication of the smart devices have become an obligatory issue. This paper reviews the security risks for mobile devices and studies several authentication techniques available for smart devices. The results from field studies enable a comparative evaluation of user-preferred authentication mechanisms and their opinions about reliability, biometric authentication and visual authentication techniques. | Syeda Mariam Muzammal Munam Ali Shah Si-Jing Zhang Hong-Ji Yang | 2016 | International Journal of Automation and computing2016，13，4： | 2 |
| 14 | Volumetric intravascular ultrasound imaging to illustrate the extent of coronary plaque burden in type 2 diabetic patients 显示文摘 | Schukro C Syeda B Yahya N | 2007 | J Diabetes Complications2007，21，6： | 1 |
| 15 | Self-assembled transparent conductive composite films of carboxylated multi-walled carbon nanotubes/poly(vinyl alcohol) electrospun nanofiber mats显示文摘 | Zhaoqiang Ding Yanping Zhu Christopher Branford-White Kan Sun Syeda Um-i-Zahra Jing Quan Huali Nie Limin Zhu | 2014 | Materials Letters2014，，： | 1 |
| 16 | Understanding the Relationship Between Health Assessment Questionnaire-disability Indes(HAQDI),Psoriasis Area Severity Indes(PASI),And Quality of Life(QOL)and Its Influence on Cost-effectiveness in Psoriatic Arthritis(PSA)显示文摘 | Gunda P Syeda SS Jugl SM | 2015 | Value Health2015，18，7： | 1 |
| 17 | Randomized comparison between intracoronary beta-radiation brachytherapy and implantation of paclitaxel-eluting stents for the treatment of diffuse in-stent restenosis 显示文摘 | Schukro C Syeda B Kirisits C | 2007 | Radiother Oncol2007，82，1： | 1 |
| 18 | Cyclooxygenase-2 induction and prostacyclin release by protease-activated receptors in endothelial ceils require cooperation between mitogen-activated protein kinase and NF-kappaB pathways 显示文摘 | Syeda F Grosjean J Houliston RA | 2006 | J Biol Chem2006，281，11： | 1 |
| 19 | Cu( I )-catalyzed three component coupling protocol for the synthesis of quinoline derivatives显示文摘 | SYEDA HUMA H Z HALDER R KALRA S S | 2002 | Tetrahedron Lett2002，43，： | 1 |
| 20 | Volumetric intravascular ul- trasound imaging to illustrate the extent of coronary plaque burden in type 2 diabetic patients 显示文摘 | Schukro C Syeda B Yahya N | 2007 | J Diabetes Complications2007，21，6： | 1 |
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